DNA helicase B

mammalian protein found in Homo sapiens
Protein protein Q21118243
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Summary

DNA helicase B is a protein[1]. It is known by 3 alternative names across languages and contexts.[2]

Key Facts

  • Part of: DNA helicase B[3], P-loop containing nucleoside triphosphate hydrolase[4], UvrD-like helicase C-terminal domain, protein family[5]
  • Has part(s): UvrD-like helicase C-terminal domain[6]
  • Molecular function: nucleotide binding[7], DNA helicase activity[8], 5'-3' DNA helicase activity[9], hydrolase activity[10], ATP binding[11], single-stranded DNA helicase activity[12], helicase activity[13], RNA binding[14], protein-containing complex binding[15]
  • Cell component: alpha DNA polymerase:primase complex[16], site of double-strand break[17], DNA replication factor A complex[18], nucleus[19], chromosome[20], cytoplasm[21]
  • Biological process: DNA-dependent DNA replication[22], DNA replication[23], DNA replication, synthesis of RNA primer[24], negative regulation of double-strand break repair via homologous recombination[25], DNA duplex unwinding[26], DNA repair[27], regulation of DNA double-strand break processing[28], cellular response to DNA damage stimulus[29], RNA processing[30]
  • Encoded by: HELB[31]
  • Found in taxon: Homo sapiens[32]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . HELB Is a Feedback Inhibitor of DNA End Resection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . HELB Is a Feedback Inhibitor of DNA End Resection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . HELB Is a Feedback Inhibitor of DNA End Resection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . HELB Is a Feedback Inhibitor of DNA End Resection. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . UniProt. Retrieved . wikidata.org.
  30. [32] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). DNA helicase B. Retrieved May 3, 2026, from https://4ort.xyz/entity/dna-helicase-b-q21118243
MLA “DNA helicase B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dna-helicase-b-q21118243.
BibTeX @misc{4ortxyz_dna-helicase-b-q21118243_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DNA helicase B}}, year = {2026}, url = {https://4ort.xyz/entity/dna-helicase-b-q21118243}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DNA helicase B — https://4ort.xyz/entity/dna-helicase-b-q21118243 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 11w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → HELB
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → nucleotide binding, DNA helicase activity, 5'-3' DNA helicase activity +8
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 5.6.2.3, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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