DISC1 scaffold protein

mammalian protein found in Rattus norvegicus

Protein protein Q28561731

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Summary

DISC1 scaffold protein is a protein^[1].

Key Facts

DISC1 scaffold protein's instance of is recorded as protein^[2].
DISC1 scaffold protein's UniProt protein ID is recorded as Q810H6^[3].
DISC1 scaffold protein's part of is recorded as Disrupted in schizophrenia 1^[4].
DISC1 scaffold protein's part of is recorded as membrane protein^[5].
DISC1 scaffold protein's RefSeq protein ID is recorded as NP_783186^[6].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_008770838^[7].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953717^[8].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953718^[9].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953719^[10].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953720^[11].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953721^[12].
DISC1 scaffold protein's RefSeq protein ID is recorded as XP_038953722^[13].
DISC1 scaffold protein's molecular function is recorded as protein binding^[14].
DISC1 scaffold protein's molecular function is recorded as cytoskeletal protein binding^[15].
DISC1 scaffold protein's molecular function is recorded as kinesin binding^[16].
DISC1 scaffold protein's molecular function is recorded as molecular adaptor activity^[17].
DISC1 scaffold protein's molecular function is recorded as protein-containing complex binding^[18].
DISC1 scaffold protein's cell component is recorded as nucleus^[19].
DISC1 scaffold protein's cell component is recorded as cytoplasm^[20].
DISC1 scaffold protein's cell component is recorded as mitochondrion^[21].
DISC1 scaffold protein's cell component is recorded as endoplasmic reticulum^[22].
DISC1 scaffold protein's cell component is recorded as centrosome^[23].
DISC1 scaffold protein's cell component is recorded as microtubule organizing center^[24].
DISC1 scaffold protein's cell component is recorded as cytosol^[25].
DISC1 scaffold protein's cell component is recorded as cytoskeleton^[26].

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Quick Facts

Instance of protein

Part of Disrupted in schizophrenia 1, membrane protein

Properties

Biological process neuron migration, positive regulation of cell-matrix adhesion, positive regulation of neuroblast proliferation, multicellular organism development, nervous system development, regulation of neuron projection development, positive regulation of neuron projection development, Wnt signaling pathway, cerebral cortex radially oriented cell migration, cell proliferation in forebrain, pyramidal neuron migration to cerebral cortex, positive regulation of Wnt signaling pathway, TOR signaling, negative regulation of protein binding, positive regulation of axon extension, mitochondrial calcium ion homeostasis, response to electrical stimulus, regulation of synaptic transmission, glutamatergic, canonical Wnt signaling pathway, cilium assembly, regulation of dendritic spine development, protein localization to centrosome, regulation of synapse maturation, non-motile cilium assembly, positive regulation of ubiquitin-dependent protein catabolic process, microtubule cytoskeleton organization

Cell component nucleus, cytoplasm, mitochondrion, endoplasmic reticulum, centrosome, microtubule organizing center, cytosol, cytoskeleton, kinesin complex, microtubule, plasma membrane, synaptic vesicle, postsynaptic density, membrane, cell junction, dynein complex, axon, ciliary basal body, cell body, synapse, postsynaptic membrane, perinuclear region of cytoplasm, central region of growth cone, intermediate filament cytoskeleton, ciliary base

Encoded by Disc1

Found in taxon brown rat

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, cytoskeletal protein binding, kinesin binding, molecular adaptor activity, protein-containing complex binding

External References (3)

Ensembl protein id ENSRNOP00000054753, ENSRNOP00000095161

Refseq protein id NP_783186, XP_008770838, XP_038953717, XP_038953718, XP_038953719, XP_038953720, XP_038953721, XP_038953722

Uniprot protein id Q810H6

🏷️ Also known as

en Disc1 en DISC1 scaffold protein en disrupted in schizophrenia 1 homolog

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ DISC1 scaffold protein — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ DISC1 scaffold protein — UniProt protein ID (P352): Q810H6. UniProt. Retrieved 2022-05-25. wikidata.org.
[4] ↑ DISC1 scaffold protein — part of (P361): Disrupted in schizophrenia 1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ DISC1 scaffold protein — part of (P361): membrane protein. wikidata.org.
[6] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): NP_783186. Q20641742. Retrieved 2022-03-20. wikidata.org.
[7] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_008770838. Q20641742. Retrieved 2022-03-20. wikidata.org.
[8] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953717. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953718. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953719. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953720. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953721. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ DISC1 scaffold protein — RefSeq protein ID (P637): XP_038953722. Q20641742. Retrieved 2022-03-20. wikidata.org.
[14] ↑ DISC1 scaffold protein — molecular function (P680): protein binding. A novel DISC1-interacting partner DISC1-Binding Zinc-finger protein: implication in the modulation of DISC1-dependent neurite outgrowth.. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ DISC1 scaffold protein — molecular function (P680): cytoskeletal protein binding. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ DISC1 scaffold protein — molecular function (P680): kinesin binding. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ DISC1 scaffold protein — molecular function (P680): molecular adaptor activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ DISC1 scaffold protein — molecular function (P680): protein-containing complex binding. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ DISC1 scaffold protein — cell component (P681): nucleus. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ DISC1 scaffold protein — cell component (P681): cytoplasm. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ DISC1 scaffold protein — cell component (P681): mitochondrion. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ DISC1 scaffold protein — cell component (P681): endoplasmic reticulum. PC12 cell model of inducible expression of mutant DISC1: new evidence for a dominant-negative mechanism of abnormal neuronal differentiation. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ DISC1 scaffold protein — cell component (P681): centrosome. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ DISC1 scaffold protein — cell component (P681): microtubule organizing center. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ DISC1 scaffold protein — cell component (P681): cytosol. DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ DISC1 scaffold protein — cell component (P681): cytoskeleton. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ DISC1 scaffold protein is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). DISC1 scaffold protein. Retrieved May 3, 2026, from https://4ort.xyz/entity/disc1-scaffold-protein-q28561731

MLA

“DISC1 scaffold protein.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/disc1-scaffold-protein-q28561731.

BibTeX

@misc{4ortxyz_disc1-scaffold-protein-q28561731_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DISC1 scaffold protein}}, year = {2026}, url = {https://4ort.xyz/entity/disc1-scaffold-protein-q28561731}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DISC1 scaffold protein — https://4ort.xyz/entity/disc1-scaffold-protein-q28561731 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/disc1-scaffold-protein-q28561731 · Last refreshed: May 3, 2026