Disabled 2 interacting protein

mammalian protein found in Mus musculus

Protein protein Q21981318

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Disabled 2 interacting protein

Summary

Disabled 2 interacting protein is a protein^[1].

Key Facts

Disabled 2 interacting protein's instance of is recorded as protein^[2].
Disabled 2 interacting protein's UniProt protein ID is recorded as Q3UHC7^[3].
Disabled 2 interacting protein's part of is recorded as C2 domain superfamily^[4].
Disabled 2 interacting protein's part of is recorded as Rho GTPase activation protein^[5].
Disabled 2 interacting protein's part of is recorded as PH-like domain superfamily^[6].
Disabled 2 interacting protein's part of is recorded as Disabled homologue 2-interacting protein^[7].
Disabled 2 interacting protein's part of is recorded as membrane protein^[8].
Disabled 2 interacting protein's part of is recorded as pleckstrin homology domain, protein family^[9].
Disabled 2 interacting protein's part of is recorded as Domain of unknown function DUF3498, protein family^[10].
Disabled 2 interacting protein's part of is recorded as C2 domain, protein family^[11].
Disabled 2 interacting protein's part of is recorded as Ras GTPase-activating domain, protein family^[12].
Disabled 2 interacting protein's part of is recorded as Ras GTPase-activating protein, conserved site, protein family^[13].
Disabled 2 interacting protein's has part is recorded as Ras GTPase-activating protein, conserved site^[14].
Disabled 2 interacting protein's has part is recorded as Domain of unknown function DUF3498^[15].
Disabled 2 interacting protein's has part is recorded as pleckstrin homology domain^[16].
Disabled 2 interacting protein's has part is recorded as Ras GTPase-activating domain^[17].
Disabled 2 interacting protein's has part is recorded as C2 domain^[18].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001001602^[19].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001107596^[20].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001107597^[21].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001277566^[22].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001277568^[23].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001277569^[24].
Disabled 2 interacting protein's RefSeq protein ID is recorded as NP_001277570^[25].
Disabled 2 interacting protein's RefSeq protein ID is recorded as XP_006498367^[26].

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Quick Facts

Instance of protein

Part of C2 domain superfamily, Rho GTPase activation protein, PH-like domain superfamily, Disabled homologue 2-interacting protein, membrane protein, pleckstrin homology domain, protein family, Domain of unknown function DUF3498, protein family, C2 domain, protein family, Ras GTPase-activating domain, protein family, Ras GTPase-activating protein, conserved site, protein family

Properties

Biological process positive regulation of protein catabolic process, positive regulation of JNK cascade, negative regulation of endothelial cell migration, positive regulation of protein serine/threonine kinase activity, positive regulation of synapse maturation, negative regulation of GTPase activity, angiogenesis, negative regulation of epithelial cell proliferation, cell cycle, regulation of protein-containing complex assembly, regulation of I-kappaB kinase/NF-kappaB signaling, negative regulation of cell population proliferation, apoptotic process, negative regulation of G0 to G1 transition, regulation of GTPase activity, positive regulation of apoptotic signaling pathway, I-kappaB phosphorylation, positive regulation of neuron migration, response to unfolded protein, negative regulation of MAP kinase activity, negative regulation of phosphatidylinositol 3-kinase activity, innate immune response, inflammatory response, regulation of p38MAPK cascade, negative regulation of fibroblast proliferation, positive regulation of MAPK cascade, negative regulation of protein phosphorylation, neuron projection morphogenesis, vascular endothelial growth factor receptor-2 signaling pathway, regulation of protein heterodimerization activity, positive regulation of epithelial cell proliferation, immune system process, positive regulation of JUN kinase activity, negative regulation of transcription by RNA polymerase II, negative regulation of I-kappaB kinase/NF-kappaB signaling, cellular response to interleukin-1, negative regulation of protein serine/threonine kinase activity, negative regulation of transcription, DNA-templated, negative regulation of NF-kappaB transcription factor activity, positive regulation of proteasomal protein catabolic process, negative regulation of vascular endothelial growth factor receptor signaling pathway, cellular response to tumor necrosis factor, positive regulation of dendrite development, cell motility involved in cerebral cortex radial glia guided migration, negative regulation of phosphatidylinositol 3-kinase signaling, multicellular organism development, tube formation, intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, layer formation in cerebral cortex, positive regulation of neuron projection development, positive regulation of apoptotic process, negative regulation of ERK1 and ERK2 cascade, negative regulation of angiogenesis, regulation of growth, cellular response to vascular endothelial growth factor stimulus, negative regulation of vascular endothelial growth factor signaling pathway, cellular response to lipopolysaccharide, negative regulation of epithelial cell migration, extrinsic apoptotic signaling pathway via death domain receptors, negative regulation of epithelial to mesenchymal transition, positive regulation of transcription by RNA polymerase II, signal transduction, negative regulation of toll-like receptor 4 signaling pathway, positive regulation of GTPase activity, reelin-mediated signaling pathway, negative regulation of canonical Wnt signaling pathway, negative regulation of cell growth, negative regulation of epidermal growth factor receptor signaling pathway, negative regulation of Ras protein signal transduction, cellular response to epidermal growth factor stimulus, negative regulation of Ras protein signal transduction

Cell component cytoplasm, membrane, intrinsic component of the cytoplasmic side of the plasma membrane, cerebellar mossy fiber, cell projection, neuronal cell body membrane, plasma membrane, endocytic vesicle, axon, soma, parallel fiber, climbing fiber, AIP1-IRE1 complex, dendrite

Encoded by Dab2ip

Found in taxon house mouse

Has part(s) Ras GTPase-activating protein, conserved site, Domain of unknown function DUF3498, pleckstrin homology domain, Ras GTPase-activating domain, C2 domain

Imported from wholeness_audit_2026-05-02

Molecular function phosphatidylinositol-3-phosphate binding, SH3 domain binding, phosphatidylinositol 3-kinase regulatory subunit binding, phosphatidylinositol-4-phosphate binding, Toll-like receptor 4 binding, kinase binding, protein phosphatase 2A binding, mitogen-activated protein kinase kinase binding, vascular endothelial growth factor receptor 2 binding, protein homodimerization activity, mitogen-activated protein kinase kinase kinase binding, 14-3-3 protein binding, protein binding, protein kinase binding, death receptor binding, signaling adaptor activity, phosphatidylinositol 3-kinase binding, identical protein binding, protein-containing complex binding, GTPase activator activity, cadherin binding, protein N-terminus binding, GTPase activator activity

External References (3)

Ensembl protein id ENSMUSP00000088532, ENSMUSP00000108607, ENSMUSP00000108610, ENSMUSP00000108616, ENSMUSP00000068832, ENSMUSP00000108605, ENSMUSP00000108611, ENSMUSP00000114915, ENSMUSP00000119058, ENSMUSP00000121506, ENSMUSP00000122341

Refseq protein id NP_001001602, NP_001107596, NP_001107597, NP_001277566, NP_001277568, NP_001277569, NP_001277570, XP_006498367, XP_006498368, XP_006498370, XP_006498374, XP_011237474, XP_011237477, XP_017174740, XP_030107915, XP_036018432, XP_036018433, XP_036018434, XP_036018435, XP_036018436, XP_036018437, XP_036018438, XP_036018439, XP_036018440, XP_036018441, XP_036018442, XP_036018443, XP_036018444, XP_036018445, XP_036018446, XP_036018447, XP_036018448, XP_036018449

Uniprot protein id Q3UHC7

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Disabled 2 interacting protein — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Disabled 2 interacting protein — UniProt protein ID (P352): Q3UHC7. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Disabled 2 interacting protein — part of (P361): C2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Disabled 2 interacting protein — part of (P361): Rho GTPase activation protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Disabled 2 interacting protein — part of (P361): PH-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Disabled 2 interacting protein — part of (P361): Disabled homologue 2-interacting protein. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Disabled 2 interacting protein — part of (P361): membrane protein. wikidata.org.
[9] ↑ Disabled 2 interacting protein — part of (P361): pleckstrin homology domain, protein family. wikidata.org.
[10] ↑ Disabled 2 interacting protein — part of (P361): Domain of unknown function DUF3498, protein family. wikidata.org.
[11] ↑ Disabled 2 interacting protein — part of (P361): C2 domain, protein family. wikidata.org.
[12] ↑ Disabled 2 interacting protein — part of (P361): Ras GTPase-activating domain, protein family. wikidata.org.
[13] ↑ Disabled 2 interacting protein — part of (P361): Ras GTPase-activating protein, conserved site, protein family. wikidata.org.
[14] ↑ Disabled 2 interacting protein — has part(s) (P527): Ras GTPase-activating protein, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Disabled 2 interacting protein — has part(s) (P527): Domain of unknown function DUF3498. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Disabled 2 interacting protein — has part(s) (P527): pleckstrin homology domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Disabled 2 interacting protein — has part(s) (P527): Ras GTPase-activating domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Disabled 2 interacting protein — has part(s) (P527): C2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001001602. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001107596. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001107597. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001277566. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001277568. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001277569. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): NP_001277570. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Disabled 2 interacting protein — RefSeq protein ID (P637): XP_006498367. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ Disabled 2 interacting protein is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Disabled 2 interacting protein. Retrieved May 3, 2026, from https://4ort.xyz/entity/disabled-2-interacting-protein

MLA

“Disabled 2 interacting protein.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/disabled-2-interacting-protein.

BibTeX

@misc{4ortxyz_disabled-2-interacting-protein_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Disabled 2 interacting protein}}, year = {2026}, url = {https://4ort.xyz/entity/disabled-2-interacting-protein}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Disabled 2 interacting protein — https://4ort.xyz/entity/disabled-2-interacting-protein (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/disabled-2-interacting-protein · Last refreshed: May 3, 2026