DExD-box helicase 39B

mammalian protein found in Homo sapiens
Protein protein Q21102336
Press Enter · cited answer in seconds

Summary

DExD-box helicase 39B is a protein[1]. It is known by 11 alternative names across languages and contexts.[2]

Key Facts

  • Part of: P-loop containing nucleoside triphosphate hydrolase[3], P-P-bond-hydrolysis-driven transporter[4], Helicase superfamily 1/2, ATP-binding domain, protein family[5], Helicase, C-terminal domain, protein family[6], DEAD/DEAH box helicase[7], RNA helicase, DEAD-box type, Q motif, protein family[8]
  • Has part(s): Helicase superfamily 1/2, ATP-binding domain[9], RNA helicase, DEAD-box type, Q motif[10], DEAD/DEAH box helicase domain[11], Helicase, C-terminal[12]
  • Molecular function: nucleotide binding[13], helicase activity[14], protein-containing complex binding[15], U4 snRNA binding[16], ATP-dependent protein binding[17], protein binding[18], nucleic acid binding[19], hydrolase activity[20], ATP binding[21], U6 snRNA binding[22], ATP-dependent activity, acting on RNA[23], ATPase activity[24], identical protein binding[25], RNA binding[26]
  • Cell component: cytoplasm[27], transcription export complex[28], nuclear matrix[29], U6 snRNP[30], spliceosomal complex[31], U4 snRNP[32], nucleus[33], nucleoplasm[34], nuclear speck[35], nucleolus[36], protein-containing complex[37]
  • Biological process: mRNA splicing, via spliceosome[38], mRNA transport[39], negative regulation of DNA damage checkpoint[40], mRNA processing[41], viral mRNA export from host cell nucleus[42], positive regulation of translation[43], mRNA export from nucleus[44], positive regulation of DNA-templated transcription, elongation[45], spliceosomal complex assembly[46], RNA secondary structure unwinding[47], RNA splicing[48], positive regulation of DNA biosynthetic process[49], liver development[50], positive regulation of cell growth involved in cardiac muscle cell development[51]
  • Encoded by: DDX39B[52]
  • Found in taxon: Homo sapiens[53]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . Retrieved . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Biochemical characterization of the ATPase and helicase activity of UAP56, an essential pre-mRNA splicing and mRNA export factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Linking transcriptional elongation and messenger RNA export to metastatic breast cancers. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . Genome instability and transcription elongation impairment in human cells depleted of THO/TREX. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . Recruitment of the complete hTREX complex is required for Kaposi's sarcoma-associated herpesvirus intronless mRNA nuclear export and virus replication. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . Genome instability and transcription elongation impairment in human cells depleted of THO/TREX. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  44. [46] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  45. [47] ↑ . Distinct activities of the DExD/H-box splicing factor hUAP56 facilitate stepwise assembly of the spliceosome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  46. [48] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  47. [49] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  48. [50] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  49. [51] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  50. [52] ↑ . UniProt. Retrieved . wikidata.org.
  51. [53] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). DExD-box helicase 39B. Retrieved May 3, 2026, from https://4ort.xyz/entity/dexd-box-helicase-39b-q21102336
MLA “DExD-box helicase 39B.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dexd-box-helicase-39b-q21102336.
BibTeX @misc{4ortxyz_dexd-box-helicase-39b-q21102336_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DExD-box helicase 39B}}, year = {2026}, url = {https://4ort.xyz/entity/dexd-box-helicase-39b-q21102336}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DExD-box helicase 39B — https://4ort.xyz/entity/dexd-box-helicase-39b-q21102336 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/dexd-box-helicase-39b-q21102336 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → DDX39B
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → nucleotide binding, helicase activity, protein-containing complex binding +12
    + 12 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 3.6.4.13, [[:toollabs:quickstatements/#/batch/261488|batch #261488]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.