Derlin 1

mammalian protein found in Homo sapiens
Protein protein Q5262653
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Derlin 1

Summary

Derlin 1 is a protein[1].

Key Facts

  • Derlin 1's instance of is recorded as protein[2].
  • Derlin 1's UniProt protein ID is recorded as Q9BUN8[3].
  • Derlin 1's part of is recorded as Derlin[4].
  • Derlin 1's part of is recorded as Endoplasmic Reticular Retrotranslocon[5].
  • Derlin 1's RefSeq protein ID is recorded as NP_001128143[6].
  • Derlin 1's RefSeq protein ID is recorded as NP_001317530[7].
  • Derlin 1's RefSeq protein ID is recorded as NP_077271[8].
  • Derlin 1's RefSeq protein ID is recorded as NP_001350892[9].
  • Derlin 1's molecular function is recorded as protein binding[10].
  • Derlin 1's molecular function is recorded as MHC class I protein binding[11].
  • Derlin 1's molecular function is recorded as ubiquitin protein ligase binding[12].
  • Derlin 1's molecular function is recorded as protease binding[13].
  • Derlin 1's molecular function is recorded as ubiquitin-specific protease binding[14].
  • Derlin 1's molecular function is recorded as ATPase binding[15].
  • Derlin 1's molecular function is recorded as signaling receptor activity[16].
  • Derlin 1's cell component is recorded as early endosome[17].
  • Derlin 1's cell component is recorded as VCP-NPL4-UFD1 AAA ATPase complex[18].
  • Derlin 1's cell component is recorded as integral component of endoplasmic reticulum membrane[19].
  • Derlin 1's cell component is recorded as Derlin-1-VIMP complex[20].
  • Derlin 1's cell component is recorded as integral component of membrane[21].
  • Derlin 1's cell component is recorded as late endosome[22].
  • Derlin 1's cell component is recorded as membrane[23].
  • Derlin 1's cell component is recorded as Derlin-1 retrotranslocation complex[24].
  • Derlin 1's cell component is recorded as endoplasmic reticulum[25].
  • Derlin 1's cell component is recorded as endoplasmic reticulum membrane[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . Q20641742. Retrieved . wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q20641742. Retrieved . wikidata.org.
  9. [10] . The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . A membrane protein required for dislocation of misfolded proteins from the ER. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . RNF185 Is a Novel E3 Ligase of Endoplasmic Reticulum-associated Degradation (ERAD) That Targets Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Signal peptide peptidase functions in ERAD to cleave the unfolded protein response regulator XBP 1u. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Regulation of retrotranslocation by p97-associated deubiquitinating enzyme ataxin-3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Identification of SVIP as an endogenous inhibitor of endoplasmic reticulum-associated degradation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Derlin 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/derlin-1
MLA “Derlin 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/derlin-1.
BibTeX @misc{4ortxyz_derlin-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Derlin 1}}, year = {2026}, url = {https://4ort.xyz/entity/derlin-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Derlin 1 — https://4ort.xyz/entity/derlin-1 (retrieved 2026-05-03)

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