Death associated protein kinase 1

mammalian protein found in Homo sapiens

Protein protein Q21155668

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Death associated protein kinase 1

Summary

Death associated protein kinase 1 is a protein^[1].

Key Facts

Death associated protein kinase 1's instance of is recorded as protein^[2].
Death associated protein kinase 1's physically interacts with is recorded as staurosporine^[3].
Death associated protein kinase 1 is a type of protein^[4].
Death associated protein kinase 1 is part of death-associated protein kinase 1^[5].
Death associated protein kinase 1 is part of Protein kinase-like domain superfamily^[6].
Death associated protein kinase 1 is part of Death-like domain superfamily^[7].
Death associated protein kinase 1 is part of P-loop containing nucleoside triphosphate hydrolase^[8].
Death associated protein kinase 1 is part of Ankyrin repeat-containing domain superfamily^[9].
Death associated protein kinase 1 is part of Ankyrin repeat-containing domain, protein family^[10].
Death associated protein kinase 1 is part of Death domain, protein family^[11].
Death associated protein kinase 1 is part of Roc domain, protein family^[12].
Death associated protein kinase 1 is part of Protein kinase domain, protein family^[13].
Death associated protein kinase 1 is part of Protein kinase, ATP binding site, protein family^[14].
Death associated protein kinase 1 is part of Ankyrin repeat, protein family^[15].
Death associated protein kinase 1 is part of Serine/threonine-protein kinase, active site, protein family^[16].
Death associated protein kinase 1 comprises protein kinase, ATP binding site^[17].
Death associated protein kinase 1 comprises Roc domain^[18].
Death associated protein kinase 1 comprises protein kinase domain^[19].
Death associated protein kinase 1 comprises ankyrin repeat^[20].
Death associated protein kinase 1 comprises serine/threonine-protein kinase, active site^[21].
Death associated protein kinase 1 comprises ankyrin repeat-containing domain^[22].
Death associated protein kinase 1 comprises death domain^[23].
Death associated protein kinase 1's molecular function is recorded as transferase activity^[24].

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Quick Facts

Instance of protein

Subclass of protein

Part of death-associated protein kinase 1, Protein kinase-like domain superfamily, Death-like domain superfamily, P-loop containing nucleoside triphosphate hydrolase, Ankyrin repeat-containing domain superfamily, Ankyrin repeat-containing domain, protein family, Death domain, protein family, Roc domain, protein family, Protein kinase domain, protein family, Protein kinase, ATP binding site, protein family, Ankyrin repeat, protein family, Serine/threonine-protein kinase, active site, protein family

Properties

Biological process regulation of apoptotic process, negative regulation of translation, phosphorylation, negative regulation of apoptotic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, regulation of autophagy, negative regulation of extrinsic apoptotic signaling pathway via death domain receptors, apoptotic signaling pathway, protein autophosphorylation, regulation of translation, extrinsic apoptotic signaling pathway via death domain receptors, signal transduction, apoptotic process, regulation of NMDA receptor activity, protein phosphorylation, positive regulation of autophagy, intracellular signal transduction, cellular response to interferon-gamma, cellular response to hydroperoxide

Cell component plasma membrane, actin cytoskeleton, cytoskeleton, cytoplasm, nucleus

Ec enzyme number 2.7.11.1

Encoded by DAPK1

Found in taxon Homo sapiens

Has part(s) protein kinase, ATP binding site, Roc domain, protein kinase domain, ankyrin repeat, serine/threonine-protein kinase, active site, ankyrin repeat-containing domain, death domain

Molecular function transferase activity, nucleotide binding, GTP binding, syntaxin-1 binding, kinase activity, protein binding, identical protein binding, calmodulin-dependent protein kinase activity, protein serine/threonine kinase activity, calmodulin binding, ATP binding, protein kinase activity, protein serine/threonine kinase activity, ATP binding

Physically interacts with staurosporine

External References (4)

Ensembl protein id ENSP00000350785, ENSP00000386135, ENSP00000417076, ENSP00000418885, ENSP00000419026, ENSP00000484267, ENSP00000417746

Pdb structure id 1IG1, 1JKK, 1JKL, 1JKS, 1JKT, 1P4F, 1WVX, 1WVY, 1YR5, 2W4J, 2W4K, 2X0G, 2XUU, 2XZS, 2Y0A, 2Y4P, 2Y4V, 2YAK, 3DFC, 3DGK, 3EH9, 3EHA, 3F5G, 3F5U, 3GU4, 3GU5, 3GU6, 3GU7, 3GU8, 3GUB, 3ZXT, 4B4L, 4PF4, 4TL0, 4TXC, 4UV0, 4YO4, 4YPD, 5AUW, 5AUU, 5AV1, 5AUY, 5AUT, 5AUX, 5AUV, 5AUZ, 5AV0, 5AV4, 5AV2, 5AV3

Refseq protein id NP_001275658, NP_001275659, NP_001275660, NP_004929, XP_005251814, XP_016869849

Uniprot protein id P53355

🏷️ Also known as

en DAPK1 en DAP kinase 1 en death-associated protein kinase 1 en Death associated protein kinase 1

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Death associated protein kinase 1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Death associated protein kinase 1 — physically interacts with (P129): staurosporine. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ Death associated protein kinase 1 — subclass of (P279): protein. Q905695. Retrieved 2016-12-01. wikidata.org.
[5] ↑ Death associated protein kinase 1 — part of (P361): death-associated protein kinase 1. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Death associated protein kinase 1 — part of (P361): Protein kinase-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Death associated protein kinase 1 — part of (P361): Death-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Death associated protein kinase 1 — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Death associated protein kinase 1 — part of (P361): Ankyrin repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Death associated protein kinase 1 — part of (P361): Ankyrin repeat-containing domain, protein family. wikidata.org.
[11] ↑ Death associated protein kinase 1 — part of (P361): Death domain, protein family. wikidata.org.
[12] ↑ Death associated protein kinase 1 — part of (P361): Roc domain, protein family. wikidata.org.
[13] ↑ Death associated protein kinase 1 — part of (P361): Protein kinase domain, protein family. wikidata.org.
[14] ↑ Death associated protein kinase 1 — part of (P361): Protein kinase, ATP binding site, protein family. wikidata.org.
[15] ↑ Death associated protein kinase 1 — part of (P361): Ankyrin repeat, protein family. wikidata.org.
[16] ↑ Death associated protein kinase 1 — part of (P361): Serine/threonine-protein kinase, active site, protein family. wikidata.org.
[17] ↑ Death associated protein kinase 1 — has part(s) (P527): protein kinase, ATP binding site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Death associated protein kinase 1 — has part(s) (P527): Roc domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Death associated protein kinase 1 — has part(s) (P527): protein kinase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Death associated protein kinase 1 — has part(s) (P527): ankyrin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Death associated protein kinase 1 — has part(s) (P527): serine/threonine-protein kinase, active site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Death associated protein kinase 1 — has part(s) (P527): ankyrin repeat-containing domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Death associated protein kinase 1 — has part(s) (P527): death domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Death associated protein kinase 1 — molecular function (P680): transferase activity. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Death associated protein kinase 1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Death associated protein kinase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/death-associated-protein-kinase-1-q21155668

MLA

“Death associated protein kinase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/death-associated-protein-kinase-1-q21155668.

BibTeX

@misc{4ortxyz_death-associated-protein-kinase-1-q21155668_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Death associated protein kinase 1}}, year = {2026}, url = {https://4ort.xyz/entity/death-associated-protein-kinase-1-q21155668}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Death associated protein kinase 1 — https://4ort.xyz/entity/death-associated-protein-kinase-1-q21155668 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/death-associated-protein-kinase-1-q21155668 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

5w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Subclass of → protein

Wikidata description → mammalian protein found in Homo sapiens

Encoded by → DAPK1

+ 13 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.7.11.1, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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