DEAD-box helicase 5

mammalian protein found in Rattus norvegicus

Protein protein Q29516942

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Summary

DEAD-box helicase 5 is a protein^[1].

Key Facts

DEAD-box helicase 5's instance of is recorded as protein^[2].
DEAD-box helicase 5's UniProt protein ID is recorded as Q6AYI1^[3].
DEAD-box helicase 5's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[4].
DEAD-box helicase 5's part of is recorded as Helicase superfamily 1/2, ATP-binding domain, protein family^[5].
DEAD-box helicase 5's part of is recorded as Helicase, C-terminal domain, protein family^[6].
DEAD-box helicase 5's part of is recorded as DEAD/DEAH box helicase^[7].
DEAD-box helicase 5's part of is recorded as RNA helicase, DEAD-box type, Q motif, protein family^[8].
DEAD-box helicase 5's part of is recorded as ATP-dependent RNA helicase DEAD-box, conserved site, protein family^[9].
DEAD-box helicase 5's part of is recorded as RNA helicase p68 repeat, protein family^[10].
DEAD-box helicase 5's has part is recorded as ATP-dependent RNA helicase DEAD-box, conserved site^[11].
DEAD-box helicase 5's has part is recorded as Helicase superfamily 1/2, ATP-binding domain^[12].
DEAD-box helicase 5's has part is recorded as RNA helicase, DEAD-box type, Q motif^[13].
DEAD-box helicase 5's has part is recorded as DEAD/DEAH box helicase domain^[14].
DEAD-box helicase 5's has part is recorded as RNA helicase p68 repeat^[15].
DEAD-box helicase 5's has part is recorded as Helicase, C-terminal^[16].
DEAD-box helicase 5's RefSeq protein ID is recorded as NP_001007614^[17].
DEAD-box helicase 5's RefSeq protein ID is recorded as XP_008766535^[18].
DEAD-box helicase 5's RefSeq protein ID is recorded as XP_038941559^[19].
DEAD-box helicase 5's molecular function is recorded as nucleotide binding^[20].
DEAD-box helicase 5's molecular function is recorded as nucleic acid binding^[21].
DEAD-box helicase 5's molecular function is recorded as RNA helicase activity^[22].
DEAD-box helicase 5's molecular function is recorded as mRNA 3'-UTR binding^[23].
DEAD-box helicase 5's molecular function is recorded as helicase activity^[24].
DEAD-box helicase 5's molecular function is recorded as protein binding^[25].
DEAD-box helicase 5's molecular function is recorded as calmodulin binding^[26].

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Quick Facts

Instance of protein

Part of P-loop containing nucleoside triphosphate hydrolase, Helicase superfamily 1/2, ATP-binding domain, protein family, Helicase, C-terminal domain, protein family, DEAD/DEAH box helicase, RNA helicase, DEAD-box type, Q motif, protein family, ATP-dependent RNA helicase DEAD-box, conserved site, protein family, RNA helicase p68 repeat, protein family

Properties

Biological process negative regulation of transcription by RNA polymerase II, alternative mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, epithelial to mesenchymal transition, regulation of transcription by RNA polymerase II, mRNA transcription, BMP signaling pathway, intracellular estrogen receptor signaling pathway, androgen receptor signaling pathway, positive regulation of DNA damage response, signal transduction by p53 class mediator, regulation of viral genome replication, regulation of androgen receptor signaling pathway, intrinsic apoptotic signaling pathway by p53 class mediator, positive regulation of production of miRNAs involved in gene silencing by miRNA

Cell component nucleus, nucleolus, catalytic step 2 spliceosome, ribonucleoprotein complex

Encoded by Ddx5

Found in taxon brown rat

Has part(s) ATP-dependent RNA helicase DEAD-box, conserved site, Helicase superfamily 1/2, ATP-binding domain, RNA helicase, DEAD-box type, Q motif, DEAD/DEAH box helicase domain, RNA helicase p68 repeat, Helicase, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function nucleotide binding, nucleic acid binding, RNA helicase activity, mRNA 3'-UTR binding, helicase activity, protein binding, calmodulin binding, ATP binding, hydrolase activity, enzyme binding, MH2 domain binding, pre-mRNA binding, ribonucleoprotein complex binding, SMAD binding, calcium-dependent protein binding, androgen receptor binding, R-SMAD binding, primary miRNA binding

External References (2)

Refseq protein id NP_001007614, XP_008766535, XP_038941559

Uniprot protein id Q6AYI1

🏷️ Also known as

en Ddx5 en ddx5 gene protein en DEAD (Asp-Glu-Ala-Asp) box helicase 5 en DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 en DEAD-box helicase 5 en p68 RNA helicase en probable ATP-dependent RNA helicase DDX5

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ DEAD-box helicase 5 — instance of (P31): protein. UniProt. Retrieved 2021-11-17. wikidata.org.
[3] ↑ DEAD-box helicase 5 — UniProt protein ID (P352): Q6AYI1. UniProt. Retrieved 2021-11-17. wikidata.org.
[4] ↑ DEAD-box helicase 5 — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ DEAD-box helicase 5 — part of (P361): Helicase superfamily 1/2, ATP-binding domain, protein family. wikidata.org.
[6] ↑ DEAD-box helicase 5 — part of (P361): Helicase, C-terminal domain, protein family. wikidata.org.
[7] ↑ DEAD-box helicase 5 — part of (P361): DEAD/DEAH box helicase. wikidata.org.
[8] ↑ DEAD-box helicase 5 — part of (P361): RNA helicase, DEAD-box type, Q motif, protein family. wikidata.org.
[9] ↑ DEAD-box helicase 5 — part of (P361): ATP-dependent RNA helicase DEAD-box, conserved site, protein family. wikidata.org.
[10] ↑ DEAD-box helicase 5 — part of (P361): RNA helicase p68 repeat, protein family. wikidata.org.
[11] ↑ DEAD-box helicase 5 — has part(s) (P527): ATP-dependent RNA helicase DEAD-box, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ DEAD-box helicase 5 — has part(s) (P527): Helicase superfamily 1/2, ATP-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ DEAD-box helicase 5 — has part(s) (P527): RNA helicase, DEAD-box type, Q motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ DEAD-box helicase 5 — has part(s) (P527): DEAD/DEAH box helicase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ DEAD-box helicase 5 — has part(s) (P527): RNA helicase p68 repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ DEAD-box helicase 5 — has part(s) (P527): Helicase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ DEAD-box helicase 5 — RefSeq protein ID (P637): NP_001007614. Q20641742. Retrieved 2021-09-07. wikidata.org.
[18] ↑ DEAD-box helicase 5 — RefSeq protein ID (P637): XP_008766535. Q20641742. Retrieved 2021-09-07. wikidata.org.
[19] ↑ DEAD-box helicase 5 — RefSeq protein ID (P637): XP_038941559. Q20641742. Retrieved 2021-09-07. wikidata.org.
[20] ↑ DEAD-box helicase 5 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ DEAD-box helicase 5 — molecular function (P680): nucleic acid binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ DEAD-box helicase 5 — molecular function (P680): RNA helicase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ DEAD-box helicase 5 — molecular function (P680): mRNA 3'-UTR binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ DEAD-box helicase 5 — molecular function (P680): helicase activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ DEAD-box helicase 5 — molecular function (P680): protein binding. p68 (Ddx5) interacts with Runx2 and regulates osteoblast differentiation. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ DEAD-box helicase 5 — molecular function (P680): calmodulin binding. Regulation of p68 RNA helicase by calmodulin and protein kinase C. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ DEAD-box helicase 5 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). DEAD-box helicase 5. Retrieved May 3, 2026, from https://4ort.xyz/entity/dead-box-helicase-5-q29516942

MLA

“DEAD-box helicase 5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dead-box-helicase-5-q29516942.

BibTeX

@misc{4ortxyz_dead-box-helicase-5-q29516942_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DEAD-box helicase 5}}, year = {2026}, url = {https://4ort.xyz/entity/dead-box-helicase-5-q29516942}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DEAD-box helicase 5 — https://4ort.xyz/entity/dead-box-helicase-5-q29516942 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/dead-box-helicase-5-q29516942 · Last refreshed: May 3, 2026