DEAD-box helicase 5

mammalian protein found in Homo sapiens

Protein protein Q21170314

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DEAD-box helicase 5

Summary

DEAD-box helicase 5 is a protein^[1]. It is known by 11 alternative names across languages and contexts.^[2]

Key Facts

DEAD-box helicase 5's instance of is recorded as protein^[3].
DEAD-box helicase 5 is part of P-loop containing nucleoside triphosphate hydrolase^[4].
DEAD-box helicase 5 is part of membrane protein^[5].
DEAD-box helicase 5 is part of Helicase superfamily 1/2, ATP-binding domain, protein family^[6].
DEAD-box helicase 5 is part of Helicase, C-terminal domain, protein family^[7].
DEAD-box helicase 5 is part of DEAD/DEAH box helicase^[8].
DEAD-box helicase 5 is part of RNA helicase, DEAD-box type, Q motif, protein family^[9].
DEAD-box helicase 5 is part of ATP-dependent RNA helicase DEAD-box, conserved site, protein family^[10].
DEAD-box helicase 5 is part of RNA helicase p68 repeat, protein family^[11].
DEAD-box helicase 5 comprises RNA helicase, DEAD-box type, Q motif^[12].
DEAD-box helicase 5 comprises RNA helicase p68 repeat^[13].
DEAD-box helicase 5 comprises ATP-dependent RNA helicase DEAD-box, conserved site^[14].
DEAD-box helicase 5 comprises DEAD/DEAH box helicase domain^[15].
DEAD-box helicase 5 comprises Helicase superfamily 1/2, ATP-binding domain^[16].
DEAD-box helicase 5 comprises Helicase, C-terminal^[17].
DEAD-box helicase 5's molecular function is recorded as nucleotide binding^[18].
DEAD-box helicase 5's molecular function is recorded as helicase activity^[19].
DEAD-box helicase 5's molecular function is recorded as calcium-dependent protein binding^[20].
DEAD-box helicase 5's molecular function is recorded as calmodulin binding^[21].
DEAD-box helicase 5's molecular function is recorded as protein binding^[22].
DEAD-box helicase 5's molecular function is recorded as androgen receptor binding^[23].
DEAD-box helicase 5's molecular function is recorded as nucleic acid binding^[24].
DEAD-box helicase 5's molecular function is recorded as enzyme binding^[25].
DEAD-box helicase 5's molecular function is recorded as pre-mRNA binding^[26].
DEAD-box helicase 5's molecular function is recorded as hydrolase activity^[27].

Why It Matters

DEAD-box helicase 5 is known by 11 alternative names across languages and contexts.^[2]

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Quick Facts

Instance of protein

Part of P-loop containing nucleoside triphosphate hydrolase, membrane protein, Helicase superfamily 1/2, ATP-binding domain, protein family, Helicase, C-terminal domain, protein family, DEAD/DEAH box helicase, RNA helicase, DEAD-box type, Q motif, protein family, ATP-dependent RNA helicase DEAD-box, conserved site, protein family, RNA helicase p68 repeat, protein family

Properties

Biological process regulation of skeletal muscle cell differentiation, regulation of transcription, DNA-templated, rhythmic process, regulation of viral genome replication, mRNA processing, mRNA transcription, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, cell growth, regulation of osteoblast differentiation, RNA secondary structure unwinding, intrinsic apoptotic signaling pathway by p53 class mediator, RNA splicing, regulation of androgen receptor signaling pathway, positive regulation of DNA damage response, signal transduction by p53 class mediator, mRNA splicing, via spliceosome, regulation of alternative mRNA splicing, via spliceosome, nuclear-transcribed mRNA catabolic process, alternative mRNA splicing, via spliceosome, regulation of transcription by RNA polymerase II, intracellular estrogen receptor signaling pathway, androgen receptor signaling pathway, epithelial to mesenchymal transition, myoblast differentiation, pri-miRNA transcription by RNA polymerase II, BMP signaling pathway, regulation of pri-miRNA transcription by RNA polymerase II, positive regulation of production of miRNAs involved in gene silencing by miRNA

Cell component catalytic step 2 spliceosome, membrane, nucleolus, spliceosomal complex, extracellular exosome, nucleus, extracellular matrix, nucleoplasm, SMAD protein complex, cytoplasm, nucleus, membrane, extracellular exosome, ribonucleoprotein complex

Ec enzyme number 3.6.4.13

Encoded by DDX5

Found in taxon Homo sapiens

Has part(s) RNA helicase, DEAD-box type, Q motif, RNA helicase p68 repeat, ATP-dependent RNA helicase DEAD-box, conserved site, DEAD/DEAH box helicase domain, Helicase superfamily 1/2, ATP-binding domain, Helicase, C-terminal

Molecular function nucleotide binding, helicase activity, calcium-dependent protein binding, calmodulin binding, protein binding, androgen receptor binding, nucleic acid binding, enzyme binding, pre-mRNA binding, hydrolase activity, ATP binding, RNA helicase activity, RNA binding, mRNA 3'-UTR binding, ribonucleoprotein complex binding, promoter-specific chromatin binding, MH2 domain binding, SMAD binding, R-SMAD binding, primary miRNA binding, RNA binding

External References (6)

Ensembl protein id ENSP00000225792, ENSP00000403085, ENSP00000440276, ENSP00000462206, ENSP00000462222, ENSP00000462885, ENSP00000463101, ENSP00000463168, ENSP00000463541, ENSP00000463903, ENSP00000463975, ENSP00000464064, ENSP00000464304, ENSP00000464337, ENSP00000464566, ENSP00000464587, ENSP00000464659, ENSP00000465791, ENSP00000485764

Mesh descriptor id C506749

Pdb structure id 3FE2, 4A4D

Refseq protein id NP_001307524, NP_001307525, NP_001307526, NP_004387

Umls cui C1570710

Uniprot protein id P17844

🏷️ Also known as

en ATP-dependent RNA helicase DDX5 en DDX5 en Ddx5 protein, human en DEAD (Asp-Glu-Ala-Asp) box helicase 5 en DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 en DEAD box-5 en DEAD-box helicase 5 en DEAD box protein 5 en DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD) en probable ATP-dependent RNA helicase DDX5 en RNA helicase p68

References

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). DEAD-box helicase 5. Retrieved May 3, 2026, from https://4ort.xyz/entity/dead-box-helicase-5

MLA “DEAD-box helicase 5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dead-box-helicase-5.

BibTeX

@misc{4ortxyz_dead-box-helicase-5_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DEAD-box helicase 5}}, year = {2026}, url = {https://4ort.xyz/entity/dead-box-helicase-5}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DEAD-box helicase 5 — https://4ort.xyz/entity/dead-box-helicase-5 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/dead-box-helicase-5 · Last refreshed: May 3, 2026

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

7w ago · Boghog · 2026-07-24 view diff on Wikidata ↗

Imported from → —

Encoded by → DDX5

Wikidata description → mammalian protein found in Homo sapiens

Molecular function → nucleotide binding, helicase activity, calcium-dependent protein binding +18

+ 13 other properties edited (see Wikidata diff for full list)

"/* wbcreateclaim-create:1| */ [[Property:P591]]: 3.6.4.13, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"

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DEAD-box helicase 5

DEAD-box helicase 5

Summary

Key Facts

Why It Matters

References

Direct Wikidata claims

Class ancestry

Aggregate / graph-position facts

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