DEAD-box helicase 3 X-linked

mammalian protein found in Homo sapiens

Protein protein Q21105627

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DEAD-box helicase 3 X-linked

Summary

DEAD-box helicase 3 X-linked is a protein^[1].

Key Facts

DEAD-box helicase 3 X-linked's instance of is recorded as protein^[2].
DEAD-box helicase 3 X-linked's UniProt protein ID is recorded as O00571^[3].
DEAD-box helicase 3 X-linked's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[4].
DEAD-box helicase 3 X-linked's part of is recorded as animal nuclear pore complex^[5].
DEAD-box helicase 3 X-linked's part of is recorded as Helicase superfamily 1/2, ATP-binding domain, protein family^[6].
DEAD-box helicase 3 X-linked's part of is recorded as Helicase, C-terminal domain, protein family^[7].
DEAD-box helicase 3 X-linked's part of is recorded as DEAD/DEAH box helicase^[8].
DEAD-box helicase 3 X-linked's part of is recorded as RNA helicase, DEAD-box type, Q motif, protein family^[9].
DEAD-box helicase 3 X-linked's part of is recorded as ATP-dependent RNA helicase DEAD-box, conserved site, protein family^[10].
DEAD-box helicase 3 X-linked's has part is recorded as RNA helicase, DEAD-box type, Q motif^[11].
DEAD-box helicase 3 X-linked's has part is recorded as ATP-dependent RNA helicase DEAD-box, conserved site^[12].
DEAD-box helicase 3 X-linked's has part is recorded as DEAD/DEAH box helicase domain^[13].
DEAD-box helicase 3 X-linked's has part is recorded as Helicase superfamily 1/2, ATP-binding domain^[14].
DEAD-box helicase 3 X-linked's has part is recorded as Helicase, C-terminal^[15].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as NP_001180345^[16].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as NP_001180346^[17].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as NP_001347^[18].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as XP_011542194^[19].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as XP_016884802^[20].
DEAD-box helicase 3 X-linked's RefSeq protein ID is recorded as NP_001350748^[21].
DEAD-box helicase 3 X-linked's PDB structure ID is recorded as 2I4I^[22].
DEAD-box helicase 3 X-linked's PDB structure ID is recorded as 2JGN^[23].
DEAD-box helicase 3 X-linked's PDB structure ID is recorded as 3JRV^[24].
DEAD-box helicase 3 X-linked's PDB structure ID is recorded as 4O2C^[25].
DEAD-box helicase 3 X-linked's PDB structure ID is recorded as 4O2E^[26].

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Quick Facts

Instance of protein

Part of P-loop containing nucleoside triphosphate hydrolase, animal nuclear pore complex, Helicase superfamily 1/2, ATP-binding domain, protein family, Helicase, C-terminal domain, protein family, DEAD/DEAH box helicase, RNA helicase, DEAD-box type, Q motif, protein family, ATP-dependent RNA helicase DEAD-box, conserved site, protein family

Properties

Biological process stress granule assembly, apoptotic process, negative regulation of translation, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, intracellular signal transduction, regulation of transcription, DNA-templated, ribosome biogenesis, negative regulation of intrinsic apoptotic signaling pathway, immune system process, chromosome segregation, negative regulation of protein-containing complex assembly, response to virus, negative regulation of apoptotic process, Wnt signaling pathway, positive regulation of translation, protein localization to cytoplasmic stress granule, transcription, DNA-templated, cellular response to osmotic stress, positive regulation of G1/S transition of mitotic cell cycle, intrinsic apoptotic signaling pathway, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cell growth, positive regulation of gene expression, mature ribosome assembly, cellular response to arsenic-containing substance, negative regulation of cell growth, positive regulation of chemokine (C-C motif) ligand 5 production, RNA secondary structure unwinding, positive regulation of apoptotic process, positive regulation of viral genome replication, viral process, innate immune response, positive regulation of translational initiation, regulation of translation, extrinsic apoptotic signaling pathway via death domain receptors, positive regulation of transcription by RNA polymerase II, positive regulation of interferon-beta production, DNA duplex unwinding, neutrophil degranulation, positive regulation of protein serine/threonine kinase activity, positive regulation of canonical Wnt signaling pathway, translational initiation

Cell component cytoplasm, eukaryotic translation initiation factor 3 complex, nuclear speck, membrane, mitochondrial outer membrane, cytosolic small ribosomal subunit, mitochondrion, cytoplasmic stress granule, extracellular exosome, nucleus, extracellular region, cytosol, secretory granule lumen, ficolin-1-rich granule lumen, nucleolus, extracellular exosome

Encoded by DDX3X

Exact match identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov

Found in taxon Homo sapiens

Has part(s) RNA helicase, DEAD-box type, Q motif, ATP-dependent RNA helicase DEAD-box, conserved site, DEAD/DEAH box helicase domain, Helicase superfamily 1/2, ATP-binding domain, Helicase, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, nucleotide binding, nucleoside-triphosphatase activity, CTPase activity, helicase activity, poly(A) binding, ribosomal small subunit binding, RNA stem-loop binding, DNA helicase activity, transcription factor binding, ATPase activity, protein binding, GTPase activity, eukaryotic initiation factor 4E binding, RNA binding, nucleic acid binding, mRNA 5'-UTR binding, translation initiation factor binding, hydrolase activity, ATP binding, RNA strand annealing activity, cadherin binding, protein serine/threonine kinase activator activity, RNA binding, cadherin binding

External References (5)

Ensembl protein id ENSP00000382840, ENSP00000392494, ENSP00000478443, ENSP00000486516, ENSP00000486720, ENSP00000487224, ENSP00000414281, ENSP00000479790, ENSP00000480647, ENSP00000486306, ENSP00000486443, ENSP00000486514, ENSP00000487062, ENSP00000487626, ENSP00000494767, ENSP00000496356, ENSP00000493819, ENSP00000496076, ENSP00000495264, ENSP00000496524, ENSP00000496222, ENSP00000494518, ENSP00000496043, ENSP00000494588, ENSP00000496663, ENSP00000495377, ENSP00000494952, ENSP00000493997, ENSP00000494905, ENSP00000496052, ENSP00000493976, ENSP00000493795, ENSP00000494887, ENSP00000493687, ENSP00000494040, ENSP00000493475, ENSP00000496257

Pdb structure id 2I4I, 2JGN, 3JRV, 4O2C, 4O2E, 4O2F, 4PX9, 4PXA, 5E7J, 5E7M, 5E7I

Refseq protein id NP_001180345, NP_001180346, NP_001347, XP_011542194, XP_016884802, NP_001350748

Transporter classification database id 1.I.1.1.3

Uniprot protein id O00571

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ DEAD-box helicase 3 X-linked — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ DEAD-box helicase 3 X-linked — UniProt protein ID (P352): O00571. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ DEAD-box helicase 3 X-linked — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ DEAD-box helicase 3 X-linked — part of (P361): animal nuclear pore complex. Retrieved 2019-10-02. wikidata.org.
[6] ↑ DEAD-box helicase 3 X-linked — part of (P361): Helicase superfamily 1/2, ATP-binding domain, protein family. wikidata.org.
[7] ↑ DEAD-box helicase 3 X-linked — part of (P361): Helicase, C-terminal domain, protein family. wikidata.org.
[8] ↑ DEAD-box helicase 3 X-linked — part of (P361): DEAD/DEAH box helicase. wikidata.org.
[9] ↑ DEAD-box helicase 3 X-linked — part of (P361): RNA helicase, DEAD-box type, Q motif, protein family. wikidata.org.
[10] ↑ DEAD-box helicase 3 X-linked — part of (P361): ATP-dependent RNA helicase DEAD-box, conserved site, protein family. wikidata.org.
[11] ↑ DEAD-box helicase 3 X-linked — has part(s) (P527): RNA helicase, DEAD-box type, Q motif. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ DEAD-box helicase 3 X-linked — has part(s) (P527): ATP-dependent RNA helicase DEAD-box, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ DEAD-box helicase 3 X-linked — has part(s) (P527): DEAD/DEAH box helicase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ DEAD-box helicase 3 X-linked — has part(s) (P527): Helicase superfamily 1/2, ATP-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ DEAD-box helicase 3 X-linked — has part(s) (P527): Helicase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): NP_001180345. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): NP_001180346. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): NP_001347. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): XP_011542194. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): XP_016884802. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ DEAD-box helicase 3 X-linked — RefSeq protein ID (P637): NP_001350748. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ DEAD-box helicase 3 X-linked — PDB structure ID (P638): 2I4I. Q905695. Retrieved 2016-08-08. wikidata.org.
[23] ↑ DEAD-box helicase 3 X-linked — PDB structure ID (P638): 2JGN. Q905695. Retrieved 2016-08-08. wikidata.org.
[24] ↑ DEAD-box helicase 3 X-linked — PDB structure ID (P638): 3JRV. Q905695. Retrieved 2016-08-08. wikidata.org.
[25] ↑ DEAD-box helicase 3 X-linked — PDB structure ID (P638): 4O2C. Q905695. Retrieved 2016-08-08. wikidata.org.
[26] ↑ DEAD-box helicase 3 X-linked — PDB structure ID (P638): 4O2E. Q905695. Retrieved 2016-08-08. wikidata.org.

Class ancestry

[1] ↑ DEAD-box helicase 3 X-linked is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). DEAD-box helicase 3 X-linked. Retrieved May 3, 2026, from https://4ort.xyz/entity/dead-box-helicase-3-x-linked

MLA

“DEAD-box helicase 3 X-linked.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/dead-box-helicase-3-x-linked.

BibTeX

@misc{4ortxyz_dead-box-helicase-3-x-linked_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{DEAD-box helicase 3 X-linked}}, year = {2026}, url = {https://4ort.xyz/entity/dead-box-helicase-3-x-linked}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): DEAD-box helicase 3 X-linked — https://4ort.xyz/entity/dead-box-helicase-3-x-linked (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/dead-box-helicase-3-x-linked · Last refreshed: May 3, 2026