cytochrome b5 reductase 3

mammalian protein found in Homo sapiens
Protein protein Q21119544
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Summary

cytochrome b5 reductase 3 is a protein[1]. It is known by 7 alternative names across languages and contexts.[2]

Key Facts

  • Physically interacts with: Viroporin 3a[3]
  • Molecular function: flavin adenine dinucleotide binding[4], ADP binding[5], NAD binding[6], FAD binding[7], cytochrome-b5 reductase activity, acting on NAD(P)H[8], AMP binding[9], oxidoreductase activity[10], protein binding[11]
  • Cell component: cytoplasm[12], endoplasmic reticulum membrane[13], lipid droplet[14], mitochondrial outer membrane[15], hemoglobin complex[16], mitochondrial inner membrane[17], extracellular exosome[18], membrane[19], mitochondrion[20], endoplasmic reticulum[21], extracellular region[22], azurophil granule lumen[23]
  • Biological process: steroid metabolic process[24], sterol biosynthetic process[25], lipid metabolism[26], cholesterol metabolic process[27], blood circulation[28], cholesterol biosynthetic process[29], steroid biosynthetic process[30], L-ascorbic acid metabolic process[31], xenobiotic metabolic process[32], neutrophil degranulation[33]
  • Encoded by: CYB5R3[34]
  • Found in taxon: Homo sapiens[35]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . BioGRID. Retrieved . thebiogrid.org. Provenance: wikidata.org.
  2. [4] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . Biochemical and spectroscopic characterization of the human mitochondrial amidoxime reducing components hmARC-1 and hmARC-2 suggests the existence of a new molybdenum enzyme family in eukaryotes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . Enzymatic instability of NADH-cytochrome b5 reductase as a cause of hereditary methemoglobinemia type I (red cell type). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Endothelial cell expression of haemoglobin α regulates nitric oxide signalling. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Identification of alternative first exons of NADH-cytochrome b5 reductase gene expressed ubiquitously in human cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Identification of major proteins in the lipid droplet-enriched fraction isolated from the human hepatocyte cell line HuH7. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Enzymatic instability of NADH-cytochrome b5 reductase as a cause of hereditary methemoglobinemia type I (red cell type). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Identification of alternative first exons of NADH-cytochrome b5 reductase gene expressed ubiquitously in human cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . Enzymatic instability of NADH-cytochrome b5 reductase as a cause of hereditary methemoglobinemia type I (red cell type). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . UniProt. Retrieved . wikidata.org.
  33. [35] ↑ . UniProt. Retrieved . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). cytochrome b5 reductase 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/cytochrome-b5-reductase-3-q21119544
MLA “cytochrome b5 reductase 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cytochrome-b5-reductase-3-q21119544.
BibTeX @misc{4ortxyz_cytochrome-b5-reductase-3-q21119544_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{cytochrome b5 reductase 3}}, year = {2026}, url = {https://4ort.xyz/entity/cytochrome-b5-reductase-3-q21119544}, note = {Accessed: 2026-05-03}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 13w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → CYB5R3
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → flavin adenine dinucleotide binding, ADP binding, NAD binding +7
    + 10 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 1.6.2.2, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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