Cyclin B1

mammalian protein found in Homo sapiens

Protein protein Q21131192

Press Enter · cited answer in seconds

Cyclin B1

Summary

Cyclin B1 is a protein^[1].

Key Facts

Cyclin B1's instance of is recorded as protein^[2].
Cyclin B1's UniProt protein ID is recorded as P14635^[3].
Cyclin B1's part of is recorded as animal nuclear pore complex^[4].
Cyclin B1's MeSH descriptor ID is recorded as D056744^[5].
Cyclin B1's RefSeq protein ID is recorded as NP_114172^[6].
Cyclin B1's RefSeq protein ID is recorded as NP_001341773^[7].
Cyclin B1's RefSeq protein ID is recorded as NP_001341774^[8].
Cyclin B1's PDB structure ID is recorded as 2B9R^[9].
Cyclin B1's PDB structure ID is recorded as 2JGZ^[10].
Cyclin B1's PDB structure ID is recorded as 4Y72^[11].
Cyclin B1's PDB structure ID is recorded as 5HQ0^[12].
Cyclin B1's PDB structure ID is recorded as 4YC3^[13].
Cyclin B1's MeSH tree code is recorded as D12.644.360.262.120.100^[14].
Cyclin B1's MeSH tree code is recorded as D12.776.167.218.120.100^[15].
Cyclin B1's MeSH tree code is recorded as D12.776.476.262.120.100^[16].
Cyclin B1's molecular function is recorded as histone kinase activity^[17].
Cyclin B1's molecular function is recorded as kinase activity^[18].
Cyclin B1's molecular function is recorded as patched binding^[19].
Cyclin B1's molecular function is recorded as protein binding^[20].
Cyclin B1's molecular function is recorded as cyclin-dependent protein serine/threonine kinase activity^[21].
Cyclin B1's molecular function is recorded as cyclin-dependent protein serine/threonine kinase activator activity^[22].
Cyclin B1's molecular function is recorded as ubiquitin-like protein ligase binding^[23].
Cyclin B1's molecular function is recorded as protein kinase binding^[24].
Cyclin B1's molecular function is recorded as protein kinase activity^[25].
Cyclin B1's molecular function is recorded as cyclin-dependent protein serine/threonine kinase regulator activity^[26].

⭐ Popularity Graph

0/100 long tail

Quick Facts

Instance of protein

Part of animal nuclear pore complex

Properties

Biological process negative regulation of protein phosphorylation, response to DDT, regulation of mitotic cell cycle spindle assembly checkpoint, positive regulation of mRNA 3'-end processing, tissue regeneration, positive regulation of fibroblast proliferation, cellular response to iron(III) ion, cellular response to organic cyclic compound, response to mechanical stimulus, positive regulation of mitotic cell cycle, in utero embryonic development, negative regulation of gene expression, regulation of cell cycle, cell division, positive regulation of attachment of spindle microtubules to kinetochore, protein phosphorylation, mitotic nuclear membrane disassembly, cellular response to fatty acid, positive regulation of cardiac muscle cell proliferation, positive regulation of cell cycle, G2/M transition of mitotic cell cycle, oocyte maturation, spermatogenesis, cell cycle, mitotic metaphase plate congression, anaphase-promoting complex-dependent catabolic process, regulation of chromosome condensation, digestive tract development, ventricular cardiac muscle cell development, cellular response to hypoxia, response to toxic substance, mitotic spindle organization, mitotic cell cycle, DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest, positive regulation of mitochondrial ATP synthesis coupled electron transport, positive regulation of G2/M transition of mitotic cell cycle, positive regulation of cyclin-dependent protein serine/threonine kinase activity, protein-containing complex assembly, regulation of cyclin-dependent protein serine/threonine kinase activity, mitotic cell cycle, mitotic metaphase plate congression, regulation of mitotic nuclear division, positive regulation of cell population proliferation, positive regulation of cell cycle, transcription initiation from RNA polymerase II promoter, regulation of mitotic cell cycle phase transition

Cell component cytoplasm, centrosome, spindle pole, membrane, nucleoplasm, microtubule organizing center, cytoskeleton, nucleus, cytosol, mitochondrial matrix, cyclin B1-CDK1 complex, cyclin-dependent protein kinase holoenzyme complex, nucleus, cytoplasm, mitochondrial matrix, centrosome, cyclin B1-CDK1 complex

Encoded by CCNB1

Found in taxon Homo sapiens

Imported from wholeness_audit_2026-05-02

Molecular function histone kinase activity, kinase activity, patched binding, protein binding, cyclin-dependent protein serine/threonine kinase activity, cyclin-dependent protein serine/threonine kinase activator activity, ubiquitin-like protein ligase binding, protein kinase binding, protein kinase activity, cyclin-dependent protein serine/threonine kinase regulator activity, protein kinase binding, histone kinase activity

External References (7)

Ensembl protein id ENSP00000256442, ENSP00000424588, ENSP00000423387, ENSP00000425103, ENSP00000426092, ENSP00000426230

Mesh descriptor id D056744

Mesh tree code D12.644.360.262.120.100, D12.776.167.218.120.100, D12.776.476.262.120.100

Pdb structure id 2B9R, 2JGZ, 4Y72, 5HQ0, 4YC3

Refseq protein id NP_114172, NP_001341773, NP_001341774

Transporter classification database id 1.I.1.1.3

Uniprot protein id P14635

🏷️ Also known as

en CCNB1 en Cyclin B1 en G2/mitotic-specific cyclin-B1

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Cyclin B1 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Cyclin B1 — UniProt protein ID (P352): P14635. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Cyclin B1 — part of (P361): animal nuclear pore complex. Retrieved 2019-10-02. wikidata.org.
[5] ↑ Cyclin B1 — MeSH descriptor ID (P486): D056744. wikidata.org.
[6] ↑ Cyclin B1 — RefSeq protein ID (P637): NP_114172. Q20641742. Retrieved 2020-05-30. wikidata.org.
[7] ↑ Cyclin B1 — RefSeq protein ID (P637): NP_001341773. Q20641742. Retrieved 2020-05-30. wikidata.org.
[8] ↑ Cyclin B1 — RefSeq protein ID (P637): NP_001341774. Q20641742. Retrieved 2020-05-30. wikidata.org.
[9] ↑ Cyclin B1 — PDB structure ID (P638): 2B9R. Q905695. Retrieved 2016-08-09. wikidata.org.
[10] ↑ Cyclin B1 — PDB structure ID (P638): 2JGZ. Q905695. Retrieved 2016-08-09. wikidata.org.
[11] ↑ Cyclin B1 — PDB structure ID (P638): 4Y72. Q905695. Retrieved 2016-08-09. wikidata.org.
[12] ↑ Cyclin B1 — PDB structure ID (P638): 5HQ0. Q905695. Retrieved 2016-08-09. wikidata.org.
[13] ↑ Cyclin B1 — PDB structure ID (P638): 4YC3. Q905695. Retrieved 2016-08-09. wikidata.org.
[14] ↑ Cyclin B1 — MeSH tree code (P672): D12.644.360.262.120.100. wikidata.org.
[15] ↑ Cyclin B1 — MeSH tree code (P672): D12.776.167.218.120.100. wikidata.org.
[16] ↑ Cyclin B1 — MeSH tree code (P672): D12.776.476.262.120.100. wikidata.org.
[17] ↑ Cyclin B1 — molecular function (P680): histone kinase activity. GOA. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Cyclin B1 — molecular function (P680): kinase activity. GOA. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Cyclin B1 — molecular function (P680): patched binding. Patched1 interacts with cyclin B1 to regulate cell cycle progression. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Cyclin B1 — molecular function (P680): protein binding. Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Cyclin B1 — molecular function (P680): cyclin-dependent protein serine/threonine kinase activity. GOA. Retrieved 2018-11-07. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Cyclin B1 — molecular function (P680): cyclin-dependent protein serine/threonine kinase activator activity. Cyclin B1/Cdk1 Coordinates Mitochondrial Respiration for Cell-Cycle G2/M Progression. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Cyclin B1 — molecular function (P680): ubiquitin-like protein ligase binding. A novel UbcH10-binding protein facilitates the ubiquitinylation of cyclin B in vitro.. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Cyclin B1 — molecular function (P680): protein kinase binding. Active cyclin B1-Cdk1 first appears on centrosomes in prophase. Retrieved 2018-06-05. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Cyclin B1 — molecular function (P680): protein kinase activity. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Cyclin B1 — molecular function (P680): cyclin-dependent protein serine/threonine kinase regulator activity. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2018-01-01. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Cyclin B1 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Cyclin B1. Retrieved May 3, 2026, from https://4ort.xyz/entity/cyclin-b1

MLA “Cyclin B1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cyclin-b1.

BibTeX

@misc{4ortxyz_cyclin-b1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cyclin B1}}, year = {2026}, url = {https://4ort.xyz/entity/cyclin-b1}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cyclin B1 — https://4ort.xyz/entity/cyclin-b1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/cyclin-b1 · Last refreshed: May 3, 2026