Cyclic GMP-AMP synthase
mammalian protein found in Homo sapiens
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Summary
Cyclic GMP-AMP synthase is a protein[1]. It is known by 9 alternative names across languages and contexts.[2]
Key Facts
- Subclass of: protein[3]
- Part of: Mab-21 domain, protein family[4]
- Has part(s): Mab-21 domain[5]
- Molecular function: nucleotidyltransferase activity[6], nucleotide binding[7], metal ion binding[8], GTP binding[9], transferase activity[10], ATP binding[11], DNA binding[12], 2',3'-cyclic GMP-AMP synthase activity[13], double-stranded DNA binding[14], chromatin binding[15], protein binding[16]
- Cell component: cytoplasm[17], cytosol[18]
- Biological process: immune system process[19], cyclic nucleotide biosynthetic process[20], cellular response to exogenous dsRNA[21], innate immune response[22], activation of innate immune response[23], defense response to virus[24], positive regulation of defense response to virus by host[25], cellular response to DNA damage stimulus[26], positive regulation of type I interferon production[27], paracrine signaling[28], positive regulation of cellular senescence[29], positive regulation of cGMP-mediated signaling[30], positive regulation of cAMP-mediated signaling[31], regulation of immunoglobulin production[32]
- Encoded by: CGAS[33]
- Found in taxon: Homo sapiens[34]