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CTLA4

protein-coding gene in the species Homo sapiens
Class type of: protein-coding gene Q14875744

Facts

13 properties
Instance of
gene
Subclass of
protein-coding gene[2]
Chromosome
human chromosome 2[11]
Cytogenetic location
2q33.2[18]
Encodes
cytotoxic T-lymphocyte associated protein 4[9]
Expressed in
lymph node, appendix, buccal mucosa cell, gonad, pancreatic epithelial cell, testicle, granulocyte, pancreatic ductal cell, superficial temporal artery, gallbladder[19][20][21][22][23][24][25][26][27][28]
Found in taxon
Homo sapiens[10]
Genetic association
rheumatoid arthritis, hypothyroidism, type-1 diabetes, type 1 diabetes mellitus 12, autoimmune lymphoproliferative syndrome due to CTLA4 haploinsuffiency[12][13][14][15][16]
Genomic end
204738683, 203873965[6][7]
Genomic start
204732509, 203853888[4][5]
HomoloGene ID
3820[3]
Ortholog
Ctla4, Ctla4[8]
Strand orientation
forward strand[17]
🏷️ Also known as
en GSE en IDDM12 en ALPS5 en CD en CD152 en CELIAC3 en CTLA-4 en CTLA4 en cytotoxic T-lymphocyte associated protein 4 en GRD4 ar بروتين مرتبط بالخلايا اللمفاوية التائية السامة 4 ar بروتين مرتبط بالخلايا اللمفاوية التائية السامة ٤ fr antigène 4 du lymphocyte T cytotoxique fr cluster de différenciation 152 ja cytotoxic T-lymphocyte associated protei zh 細胞毒性T淋巴細胞相關抗原4 zh-hans 细胞毒性T淋巴细胞相关抗原4
🔖 Identifiers · 11
Image (Wikimedia Commons)
CTLA4 Crystal Structure.rsh.png ↗
CIViC gene ID
1285
Ensembl gene ID
ENSG00000163599
Ensembl transcript ID
ENST00000487393, ENST00000295854, ENST00000427473, ENST00000650075, ENST00000648405, ENST00000696479, ENST00000696049
Entrez Gene ID
1493
Exact match
identifiers.org
HGNC ID
2505
HGNC gene symbol
CTLA4
OMIM ID
123890
RefSeq RNA ID
NM_001037631, NM_005214
UMLS CUI
C1332802

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Summary

CTLA4 is a gene[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Ensembl Release 87. wikidata.org.
  2. [3] ↑ . NCBI Gene. Retrieved . wikidata.org.
  3. [4] ↑ . ensembl Release 106. wikidata.org.
  4. [5] ↑ . ensembl Release 106. wikidata.org.
  5. [6] ↑ . ensembl Release 106. wikidata.org.
  6. [7] ↑ . ensembl Release 106. wikidata.org.
  7. [8] ↑ . HomoloGene build68. omabrowser.org. Provenance: wikidata.org.
  8. [9] ↑ . UniProt. Retrieved . wikidata.org.
  9. [10] ↑ . ensembl Release 106. wikidata.org.
  10. [11] ↑ . ensembl Release 106. wikidata.org.
  11. [12] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  12. [13] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  13. [14] ↑ . Phenocarta. Retrieved . gemma.msl.ubc.ca. Provenance: wikidata.org.
  14. [15] ↑ . UniProt. Retrieved . wikidata.org.
  15. [16] ↑ . ClinGen. Retrieved . search.clinicalgenome.org. Provenance: wikidata.org.
  16. [17] ↑ . ensembl Release 106. wikidata.org.
  17. [18] ↑ . NCBI Gene. Retrieved . wikidata.org.
  18. [19] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  19. [20] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  20. [21] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  21. [22] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  22. [23] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  23. [24] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  24. [25] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  25. [26] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  26. [27] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.
  27. [28] ↑ . Bgee. Retrieved . bgee.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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APA 4ort.xyz Knowledge Graph. (2026). CTLA4. Retrieved October 29, 2026, from https://4ort.xyz/entity/ctla4-q14875744
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BibTeX @misc{4ortxyz_ctla4-q14875744_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CTLA4}}, year = {2026}, url = {https://4ort.xyz/entity/ctla4-q14875744}, note = {Accessed: 2026-10-29}}
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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 24w ago · Mathieu Kappler · 2026-05-20 view diff on Wikidata ↗
    HGNC gene symbol → CTLA4
    Genetic association → rheumatoid arthritis, hypothyroidism, type-1 diabetes +2
    RefSeq RNA ID → NM_001037631, NM_005214
    Exact match → http://identifiers.org/ncbigene/1493
    + 22 other properties edited (see Wikidata diff for full list)
    "Changed [gsw] labels, descriptions or aliases: QuickStatements 3.0 batch #32527: human gene name and description in Alemannic"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.