Claudin 5

mammalian protein found in Homo sapiens
Protein protein Q21100765
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Claudin 5

Summary

Claudin 5 is a protein[1].

Key Facts

  • Claudin 5's instance of is recorded as protein[2].
  • Claudin 5's UniProt protein ID is recorded as O00501[3].
  • Claudin 5's part of is recorded as Claudin-5[4].
  • Claudin 5's part of is recorded as claudins[5].
  • Claudin 5's has part is recorded as Claudin, conserved site[6].
  • Claudin 5's RefSeq protein ID is recorded as NP_001124333[7].
  • Claudin 5's RefSeq protein ID is recorded as NP_003268[8].
  • Claudin 5's RefSeq protein ID is recorded as NP_001349995[9].
  • Claudin 5's RefSeq protein ID is recorded as NP_001349996[10].
  • Claudin 5's molecular function is recorded as structural molecule activity[11].
  • Claudin 5's molecular function is recorded as identical protein binding[12].
  • Claudin 5's cell component is recorded as membrane[13].
  • Claudin 5's cell component is recorded as apicolateral plasma membrane[14].
  • Claudin 5's cell component is recorded as cortical actin cytoskeleton[15].
  • Claudin 5's cell component is recorded as cell-cell junction[16].
  • Claudin 5's cell component is recorded as integral component of membrane[17].
  • Claudin 5's cell component is recorded as bicellular tight junction[18].
  • Claudin 5's cell component is recorded as plasma membrane[19].
  • Claudin 5's cell component is recorded as cell junction[20].
  • Claudin 5's biological process is recorded as cell-cell junction assembly[21].
  • Claudin 5's biological process is recorded as transforming growth factor beta receptor signaling pathway[22].
  • Claudin 5's biological process is recorded as outflow tract morphogenesis[23].
  • Claudin 5's biological process is recorded as learning[24].
  • Claudin 5's biological process is recorded as positive regulation of establishment of endothelial barrier[25].
  • Claudin 5's biological process is recorded as roof of mouth development[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . Retrieved . wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q20641742. Retrieved . wikidata.org.
  9. [10] . Q20641742. Retrieved . wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Tumor Necrosis Factor Disrupts Claudin-5 Endothelial Tight Junction Barriers in Two Distinct NF-κB-Dependent Phases. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Anthrax lethal toxin downregulates claudin-5 expression in human endothelial tight junctions. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but Not Human Umbilical Vein Endothelial Cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Claudin-5 Controls Intercellular Barriers of Human Dermal Microvascular but Not Human Umbilical Vein Endothelial Cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Claudin 5. Retrieved May 3, 2026, from https://4ort.xyz/entity/claudin-5
MLA “Claudin 5.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/claudin-5.
BibTeX @misc{4ortxyz_claudin-5_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Claudin 5}}, year = {2026}, url = {https://4ort.xyz/entity/claudin-5}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Claudin 5 — https://4ort.xyz/entity/claudin-5 (retrieved 2026-05-03)

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