Class II major histocompatibility complex transactivator

mammalian protein found in Homo sapiens

Protein protein Q5011707

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Class II major histocompatibility complex transactivator

Summary

Class II major histocompatibility complex transactivator is a protein^[1].

Key Facts

Class II major histocompatibility complex transactivator's instance of is recorded as protein^[2].
Class II major histocompatibility complex transactivator's UniProt protein ID is recorded as P33076^[3].
Class II major histocompatibility complex transactivator's part of is recorded as MHC class II transactivator^[4].
Class II major histocompatibility complex transactivator's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[5].
Class II major histocompatibility complex transactivator's part of is recorded as Leucine-rich repeat domain superfamily^[6].
Class II major histocompatibility complex transactivator's part of is recorded as NACHT nucleoside triphosphatase family^[7].
Class II major histocompatibility complex transactivator's part of is recorded as Leucine-rich repeat, protein family^[8].
Class II major histocompatibility complex transactivator's has part is recorded as Leucine-rich repeat^[9].
Class II major histocompatibility complex transactivator's has part is recorded as NACHT nucleoside triphosphatase domain^[10].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as NP_000237^[11].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as NP_001273331^[12].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as NP_001273332^[13].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_006720943^[14].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520786^[15].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520787^[16].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520788^[17].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520789^[18].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520791^[19].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520792^[20].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520793^[21].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_011520796^[22].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_024306048^[23].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as XP_024306049^[24].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as NP_001366259^[25].
Class II major histocompatibility complex transactivator's RefSeq protein ID is recorded as NP_001366260^[26].

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Quick Facts

Instance of protein

Part of MHC class II transactivator, P-loop containing nucleoside triphosphate hydrolase, Leucine-rich repeat domain superfamily, NACHT nucleoside triphosphatase family, Leucine-rich repeat, protein family

Properties

Biological process positive regulation of MHC class II biosynthetic process, regulation of transcription, DNA-templated, response to interferon-gamma, phosphorylation, interferon-gamma-mediated signaling pathway, response to antibiotic, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, positive regulation of transcription, DNA-templated, immune response, negative regulation of transcription, DNA-templated, positive regulation of MHC class I biosynthetic process, negative regulation of collagen biosynthetic process, positive regulation of transcription by RNA polymerase II, inflammatory response, positive regulation of MHC class I biosynthetic process, positive regulation of MHC class II biosynthetic process, positive regulation of transcription by RNA polymerase II

Cell component PML body, nucleoplasm, nucleus

Encoded by CIITA

Exact match purl.uniprot.org

Found in taxon Homo sapiens

Has part(s) Leucine-rich repeat, NACHT nucleoside triphosphatase domain

Imported from wholeness_audit_2026-05-02

Molecular function transferase activity, DNA binding, nucleotide binding, transcription coactivator activity, GTP binding, kinase activity, protein C-terminus binding, protein binding, acyltransferase activity, ATP binding, protein-containing complex binding

External References (3)

Ensembl protein id ENSP00000371257, ENSP00000316328, ENSP00000459608, ENSP00000459829, ENSP00000484761, ENSP00000485010, ENSP00000489907, ENSP00000490205, ENSP00000495431, ENSP00000496240

Refseq protein id NP_000237, NP_001273331, NP_001273332, XP_006720943, XP_011520786, XP_011520787, XP_011520788, XP_011520789, XP_011520791, XP_011520792, XP_011520793, XP_011520796, XP_024306048, XP_024306049, NP_001366259, NP_001366260, NP_001366261, NP_001366262, NP_001366263

Uniprot protein id P33076

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Class II major histocompatibility complex transactivator — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Class II major histocompatibility complex transactivator — UniProt protein ID (P352): P33076. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Class II major histocompatibility complex transactivator — part of (P361): MHC class II transactivator. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Class II major histocompatibility complex transactivator — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Class II major histocompatibility complex transactivator — part of (P361): Leucine-rich repeat domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Class II major histocompatibility complex transactivator — part of (P361): NACHT nucleoside triphosphatase family. wikidata.org.
[8] ↑ Class II major histocompatibility complex transactivator — part of (P361): Leucine-rich repeat, protein family. wikidata.org.
[9] ↑ Class II major histocompatibility complex transactivator — has part(s) (P527): Leucine-rich repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Class II major histocompatibility complex transactivator — has part(s) (P527): NACHT nucleoside triphosphatase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): NP_000237. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): NP_001273331. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): NP_001273332. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_006720943. Q20641742. Retrieved 2020-05-30. wikidata.org.
[15] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520786. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520787. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520788. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520789. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520791. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520792. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520793. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_011520796. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_024306048. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): XP_024306049. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): NP_001366259. Q20641742. Retrieved 2020-04-04. wikidata.org.
[26] ↑ Class II major histocompatibility complex transactivator — RefSeq protein ID (P637): NP_001366260. Q20641742. Retrieved 2020-04-04. wikidata.org.

Class ancestry

[1] ↑ Class II major histocompatibility complex transactivator is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Class II major histocompatibility complex transactivator. Retrieved May 3, 2026, from https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator

MLA

“Class II major histocompatibility complex transactivator.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator.

BibTeX

@misc{4ortxyz_class-ii-major-histocompatibility-complex-transactivator_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Class II major histocompatibility complex transactivator}}, year = {2026}, url = {https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Class II major histocompatibility complex transactivator — https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/class-ii-major-histocompatibility-complex-transactivator · Last refreshed: May 3, 2026