Ciliary neurotrophic factor

mammalian protein found in Rattus norvegicus
Protein protein Q28558655
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Ciliary neurotrophic factor

Summary

Ciliary neurotrophic factor is a protein[1].

Key Facts

  • Ciliary neurotrophic factor's instance of is recorded as protein[2].
  • Ciliary neurotrophic factor's subclass of is recorded as protein[3].
  • Ciliary neurotrophic factor's UniProt protein ID is recorded as P20294[4].
  • Ciliary neurotrophic factor's part of is recorded as four-helical cytokine-like, core[5].
  • Ciliary neurotrophic factor's part of is recorded as ciliary neurotrophic factor, CNTF[6].
  • Ciliary neurotrophic factor's RefSeq protein ID is recorded as NP_037298[7].
  • Ciliary neurotrophic factor's molecular function is recorded as cytokine activity[8].
  • Ciliary neurotrophic factor's molecular function is recorded as ciliary neurotrophic factor receptor binding[9].
  • Ciliary neurotrophic factor's molecular function is recorded as growth factor activity[10].
  • Ciliary neurotrophic factor's cell component is recorded as extracellular space[11].
  • Ciliary neurotrophic factor's cell component is recorded as nucleus[12].
  • Ciliary neurotrophic factor's cell component is recorded as cytoplasm[13].
  • Ciliary neurotrophic factor's cell component is recorded as cytosol[14].
  • Ciliary neurotrophic factor's cell component is recorded as axon[15].
  • Ciliary neurotrophic factor's cell component is recorded as plasma membrane bounded cell projection cytoplasm[16].
  • Ciliary neurotrophic factor's cell component is recorded as soma[17].
  • Ciliary neurotrophic factor's biological process is recorded as receptor signaling pathway via JAK-STAT[18].
  • Ciliary neurotrophic factor's biological process is recorded as multicellular organism development[19].
  • Ciliary neurotrophic factor's biological process is recorded as nervous system development[20].
  • Ciliary neurotrophic factor's biological process is recorded as positive regulation of cell population proliferation[21].
  • Ciliary neurotrophic factor's biological process is recorded as response to light intensity[22].
  • Ciliary neurotrophic factor's biological process is recorded as regulation of signaling receptor activity[23].
  • Ciliary neurotrophic factor's biological process is recorded as positive regulation of phosphatidylinositol 3-kinase signaling[24].
  • Ciliary neurotrophic factor's biological process is recorded as cell differentiation[25].
  • Ciliary neurotrophic factor's biological process is recorded as positive regulation of cell growth[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . Q905695. Retrieved . wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . Q20641742. Retrieved . wikidata.org.
  7. [8] . Cross-linking identifies leukemia inhibitory factor-binding protein as a ciliary neurotrophic factor receptor component. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . The receptor for ciliary neurotrophic factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Corticostriatopallidal neuroprotection by adenovirus-mediated ciliary neurotrophic factor gene transfer in a rat model of progressive striatal degeneration. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . Molecular cloning, expression and regional distribution of rat ciliary neurotrophic factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Ciliary neurotrophic factor in the olfactory bulb of rats and mice. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . The complex of ciliary neurotrophic factor-ciliary neurotrophic factor receptor alpha up-regulates connexin43 and intercellular coupling in astrocytes via the Janus tyrosine kinase/signal transducer and activator of transcription pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Rapid protein kinase C-dependent reduction of rat skeletal muscle voltage-gated sodium channels by ciliary neurotrophic factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . Brain-Derived Neurotrophic Factor as a Biomarker in Primary Open-Angle Glaucoma. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Cellular mechanisms associated with spontaneous and ciliary neurotrophic factor-cAMP-induced survival and axonal regeneration of adult retinal ganglion cells. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Ciliary Neurotrophic Factor Activates Spinal Cord Astrocytes, Stimulating Their Production and Release of Fibroblast Growth Factor-2, to Increase Motor Neuron Survival. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Ciliary neurotrophic factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/ciliary-neurotrophic-factor
MLA “Ciliary neurotrophic factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ciliary-neurotrophic-factor.
BibTeX @misc{4ortxyz_ciliary-neurotrophic-factor_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ciliary neurotrophic factor}}, year = {2026}, url = {https://4ort.xyz/entity/ciliary-neurotrophic-factor}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ciliary neurotrophic factor — https://4ort.xyz/entity/ciliary-neurotrophic-factor (retrieved 2026-05-03)

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