Chromodomain helicase DNA binding protein 8

mammalian protein found in Homo sapiens

Protein protein Q21102093

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Chromodomain helicase DNA binding protein 8

Summary

Chromodomain helicase DNA binding protein 8 is a protein^[1].

Key Facts

Chromodomain helicase DNA binding protein 8's instance of is recorded as protein^[2].
Chromodomain helicase DNA binding protein 8's UniProt protein ID is recorded as Q9HCK8^[3].
Chromodomain helicase DNA binding protein 8's part of is recorded as Chromodomain-helicase-DNA-binding protein 8^[4].
Chromodomain helicase DNA binding protein 8's part of is recorded as Chromo-like domain superfamily^[5].
Chromodomain helicase DNA binding protein 8's part of is recorded as BRK domain superfamily^[6].
Chromodomain helicase DNA binding protein 8's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[7].
Chromodomain helicase DNA binding protein 8's part of is recorded as SNF2-like, N-terminal domain superfamily^[8].
Chromodomain helicase DNA binding protein 8's part of is recorded as Helicase superfamily 1/2, ATP-binding domain, protein family^[9].
Chromodomain helicase DNA binding protein 8's part of is recorded as Chromo domain, protein family^[10].
Chromodomain helicase DNA binding protein 8's part of is recorded as Helicase, C-terminal domain, protein family^[11].
Chromodomain helicase DNA binding protein 8's part of is recorded as BRK domain, protein family^[12].
Chromodomain helicase DNA binding protein 8's part of is recorded as SNF2-related, N-terminal domain, protein family^[13].
Chromodomain helicase DNA binding protein 8's part of is recorded as Chromo/chromo shadow domain, protein family^[14].
Chromodomain helicase DNA binding protein 8's has part is recorded as SNF2-related, N-terminal domain^[15].
Chromodomain helicase DNA binding protein 8's has part is recorded as Chromo/chromo shadow domain^[16].
Chromodomain helicase DNA binding protein 8's has part is recorded as Helicase superfamily 1/2, ATP-binding domain^[17].
Chromodomain helicase DNA binding protein 8's has part is recorded as BRK domain^[18].
Chromodomain helicase DNA binding protein 8's has part is recorded as Chromo domain^[19].
Chromodomain helicase DNA binding protein 8's has part is recorded as Helicase, C-terminal^[20].
Chromodomain helicase DNA binding protein 8's RefSeq protein ID is recorded as NP_001164100^[21].
Chromodomain helicase DNA binding protein 8's RefSeq protein ID is recorded as NP_065971^[22].
Chromodomain helicase DNA binding protein 8's PDB structure ID is recorded as 2CKA^[23].
Chromodomain helicase DNA binding protein 8's PDB structure ID is recorded as 2DL6^[24].
Chromodomain helicase DNA binding protein 8's molecular function is recorded as DNA binding^[25].
Chromodomain helicase DNA binding protein 8's molecular function is recorded as nucleotide binding^[26].

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Quick Facts

Instance of protein

Part of Chromodomain-helicase-DNA-binding protein 8, Chromo-like domain superfamily, BRK domain superfamily, P-loop containing nucleoside triphosphate hydrolase, SNF2-like, N-terminal domain superfamily, Helicase superfamily 1/2, ATP-binding domain, protein family, Chromo domain, protein family, Helicase, C-terminal domain, protein family, BRK domain, protein family, SNF2-related, N-terminal domain, protein family, Chromo/chromo shadow domain, protein family

Properties

Biological process regulation of transcription, DNA-templated, negative regulation of transcription by RNA polymerase II, Wnt signaling pathway, transcription, DNA-templated, positive regulation of transcription, DNA-templated, brain development, digestive tract development, positive regulation of transcription by RNA polymerase III, negative regulation of canonical Wnt signaling pathway, positive regulation of transcription by RNA polymerase II, DNA duplex unwinding, chromatin organization, negative regulation of Wnt signaling pathway, negative regulation of transcription, DNA-templated, canonical Wnt signaling pathway, negative regulation of Wnt signaling pathway, negative regulation of apoptotic process, negative regulation of transcription, DNA-templated, positive regulation of transcription, DNA-templated, in utero embryonic development, startle response, brain development, social behavior, digestive tract development, prepulse inhibition, negative regulation of canonical Wnt signaling pathway, negative regulation of fibroblast apoptotic process

Cell component nucleoplasm, MLL1 complex, nucleus, protein-containing complex, MLL1 complex, protein-containing complex

Encoded by CHD8

Found in taxon Homo sapiens

Has part(s) SNF2-related, N-terminal domain, Chromo/chromo shadow domain, Helicase superfamily 1/2, ATP-binding domain, BRK domain, Chromo domain, Helicase, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, nucleotide binding, ATP-dependent activity, acting on DNA, helicase activity, chromatin binding, methylated histone binding, hydrolase activity, acting on acid anhydrides, DNA helicase activity, protein binding, hydrolase activity, ATP binding, p53 binding, beta-catenin binding, histone binding, p53 binding, DNA helicase activity, beta-catenin binding, ATP-dependent activity, acting on DNA, histone binding, chromatin binding, armadillo repeat domain binding

External References (4)

Ensembl protein id ENSP00000382863, ENSP00000406288, ENSP00000451601, ENSP00000450860, ENSP00000450957, ENSP00000451071, ENSP00000451442, ENSP00000496730, ENSP00000495240, ENSP00000496565, ENSP00000495174, ENSP00000495070, ENSP00000496722, ENSP00000493865, ENSP00000494402

Pdb structure id 2CKA, 2DL6

Refseq protein id NP_001164100, NP_065971

Uniprot protein id Q9HCK8

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Chromodomain helicase DNA binding protein 8 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Chromodomain helicase DNA binding protein 8 — UniProt protein ID (P352): Q9HCK8. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Chromodomain-helicase-DNA-binding protein 8. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Chromo-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): BRK domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): SNF2-like, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Helicase superfamily 1/2, ATP-binding domain, protein family. wikidata.org.
[10] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Chromo domain, protein family. wikidata.org.
[11] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Helicase, C-terminal domain, protein family. wikidata.org.
[12] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): BRK domain, protein family. wikidata.org.
[13] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): SNF2-related, N-terminal domain, protein family. wikidata.org.
[14] ↑ Chromodomain helicase DNA binding protein 8 — part of (P361): Chromo/chromo shadow domain, protein family. wikidata.org.
[15] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): SNF2-related, N-terminal domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): Chromo/chromo shadow domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): Helicase superfamily 1/2, ATP-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): BRK domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): Chromo domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Chromodomain helicase DNA binding protein 8 — has part(s) (P527): Helicase, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Chromodomain helicase DNA binding protein 8 — RefSeq protein ID (P637): NP_001164100. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Chromodomain helicase DNA binding protein 8 — RefSeq protein ID (P637): NP_065971. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Chromodomain helicase DNA binding protein 8 — PDB structure ID (P638): 2CKA. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Chromodomain helicase DNA binding protein 8 — PDB structure ID (P638): 2DL6. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Chromodomain helicase DNA binding protein 8 — molecular function (P680): DNA binding. CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Chromodomain helicase DNA binding protein 8 — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Chromodomain helicase DNA binding protein 8 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Chromodomain helicase DNA binding protein 8. Retrieved May 3, 2026, from https://4ort.xyz/entity/chromodomain-helicase-dna-binding-protein-8-q21102093

MLA

“Chromodomain helicase DNA binding protein 8.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/chromodomain-helicase-dna-binding-protein-8-q21102093.

BibTeX

@misc{4ortxyz_chromodomain-helicase-dna-binding-protein-8-q21102093_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Chromodomain helicase DNA binding protein 8}}, year = {2026}, url = {https://4ort.xyz/entity/chromodomain-helicase-dna-binding-protein-8-q21102093}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Chromodomain helicase DNA binding protein 8 — https://4ort.xyz/entity/chromodomain-helicase-dna-binding-protein-8-q21102093 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/chromodomain-helicase-dna-binding-protein-8-q21102093 · Last refreshed: May 3, 2026