Cellular communication network factor 2

mammalian protein found in Mus musculus

Protein protein Q14907754

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Cellular communication network factor 2

Summary

Cellular communication network factor 2 is a protein^[1].

Key Facts

Cellular communication network factor 2's instance of is recorded as protein^[2].
Cellular communication network factor 2's subclass of is recorded as protein^[3].
Cellular communication network factor 2's UniProt protein ID is recorded as P29268^[4].
Cellular communication network factor 2's part of is recorded as IGFBP-related, CNN^[5].
Cellular communication network factor 2's part of is recorded as Thrombospondin type-1 (TSP1) repeat superfamily^[6].
Cellular communication network factor 2's part of is recorded as Growth factor receptor cysteine-rich domain superfamily^[7].
Cellular communication network factor 2's part of is recorded as Glycoprotein hormone subunit beta, protein family^[8].
Cellular communication network factor 2's part of is recorded as VWFC domain, protein family^[9].
Cellular communication network factor 2's part of is recorded as Cystine knot, C-terminal domain, protein family^[10].
Cellular communication network factor 2's part of is recorded as Insulin-like growth factor-binding protein, IGFBP family^[11].
Cellular communication network factor 2's part of is recorded as Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family^[12].
Cellular communication network factor 2's part of is recorded as Thrombospondin type-1 (TSP1) repeat, protein family^[13].
Cellular communication network factor 2's has part is recorded as Insulin-like growth factor-binding protein, IGFBP^[14].
Cellular communication network factor 2's has part is recorded as Glycoprotein hormone subunit beta^[15].
Cellular communication network factor 2's has part is recorded as Thrombospondin type-1 (TSP1) repeat^[16].
Cellular communication network factor 2's has part is recorded as VWFC domain^[17].
Cellular communication network factor 2's has part is recorded as Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site^[18].
Cellular communication network factor 2's has part is recorded as Cystine knot, C-terminal^[19].
Cellular communication network factor 2's RefSeq protein ID is recorded as NP_034347^[20].
Cellular communication network factor 2's molecular function is recorded as insulin-like growth factor binding^[21].
Cellular communication network factor 2's molecular function is recorded as heparin binding^[22].
Cellular communication network factor 2's molecular function is recorded as integrin binding^[23].
Cellular communication network factor 2's molecular function is recorded as protein C-terminus binding^[24].
Cellular communication network factor 2's molecular function is recorded as growth factor activity^[25].
Cellular communication network factor 2's molecular function is recorded as fibronectin binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Subclass of protein

Part of IGFBP-related, CNN, Thrombospondin type-1 (TSP1) repeat superfamily, Growth factor receptor cysteine-rich domain superfamily, Glycoprotein hormone subunit beta, protein family, VWFC domain, protein family, Cystine knot, C-terminal domain, protein family, Insulin-like growth factor-binding protein, IGFBP family, Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family, Thrombospondin type-1 (TSP1) repeat, protein family

Properties

Biological process cell differentiation, regulation of chondrocyte differentiation, response to amino acid, DNA biosynthetic process, response to estradiol, response to organic cyclic compound, response to anoxia, response to fatty acid, ossification, lung development, response to mineralocorticoid, response to peptide hormone, positive regulation of JNK cascade, response to glucose, negative regulation of gene expression, reactive oxygen species metabolic process, fibroblast growth factor receptor signaling pathway, cell adhesion, connective tissue development, regulation of cell growth, angiogenesis, tissue homeostasis, chondrocyte proliferation, positive regulation of cell differentiation, positive regulation of ERK1 and ERK2 cascade, integrin-mediated signaling pathway, cell-matrix adhesion, cell migration, cartilage condensation, positive regulation of stress fiber assembly, positive regulation of cardiac muscle contraction, positive regulation of protein phosphorylation, extracellular matrix constituent secretion, ageing, positive regulation of cell population proliferation, positive regulation of cell death, positive regulation of cell activation, intracellular signal transduction, positive regulation of gene expression, positive regulation of G0 to G1 transition, positive regulation of collagen biosynthetic process, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, cell-cell signaling, negative regulation of cell death, regulation of signaling receptor activity, positive regulation of protein phosphorylation, cell adhesion, positive regulation of cell population proliferation, positive regulation of gene expression, positive regulation of cell death, positive regulation of collagen biosynthetic process, intracellular signal transduction, positive regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of cell activation, positive regulation of cardiac muscle contraction, negative regulation of cell death, extracellular matrix constituent secretion, positive regulation of G0 to G1 transition

Cell component extracellular region, cell cortex, cytosol, cis-Golgi network, perinuclear region of cytoplasm, extracellular space, extracellular space, cis-Golgi network, cytosol, cell cortex, extracellular matrix, perinuclear region of cytoplasm

Encoded by Ccn2

Found in taxon house mouse

Has part(s) Insulin-like growth factor-binding protein, IGFBP, Glycoprotein hormone subunit beta, Thrombospondin type-1 (TSP1) repeat, VWFC domain, Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, Cystine knot, C-terminal

Imported from wholeness_audit_2026-05-02

Molecular function insulin-like growth factor binding, heparin binding, integrin binding, protein C-terminus binding, growth factor activity, fibronectin binding, fibronectin binding, integrin binding, growth factor activity, heparin binding

External References (3)

Ensembl protein id ENSMUSP00000020171, ENSMUSP00000135147, ENSMUSP00000135212

Refseq protein id NP_034347

Uniprot protein id P29268

🏷️ Also known as

en Ccn2 en CCN family member 2 en cellular communication network factor 1 en Cellular communication network factor 2 en connective tissue growth factor en Connective tissue growth factor precursor (CTGF) (FISP-12 protein) (Hypertrophic chondrocyte-specific protein 24) en Ctgf en fibroblast inducible secreated protein en fibroblast inducible secreted protein en hypertrophic chondrocyte-specific gene product 24 en hypertrophic chondrocyte-specific protein 24 en Protein FISP-12

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Cellular communication network factor 2 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Cellular communication network factor 2 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Cellular communication network factor 2 — UniProt protein ID (P352): P29268. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Cellular communication network factor 2 — part of (P361): IGFBP-related, CNN. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Cellular communication network factor 2 — part of (P361): Thrombospondin type-1 (TSP1) repeat superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Cellular communication network factor 2 — part of (P361): Growth factor receptor cysteine-rich domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Cellular communication network factor 2 — part of (P361): Glycoprotein hormone subunit beta, protein family. wikidata.org.
[9] ↑ Cellular communication network factor 2 — part of (P361): VWFC domain, protein family. wikidata.org.
[10] ↑ Cellular communication network factor 2 — part of (P361): Cystine knot, C-terminal domain, protein family. wikidata.org.
[11] ↑ Cellular communication network factor 2 — part of (P361): Insulin-like growth factor-binding protein, IGFBP family. wikidata.org.
[12] ↑ Cellular communication network factor 2 — part of (P361): Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site, protein family. wikidata.org.
[13] ↑ Cellular communication network factor 2 — part of (P361): Thrombospondin type-1 (TSP1) repeat, protein family. wikidata.org.
[14] ↑ Cellular communication network factor 2 — has part(s) (P527): Insulin-like growth factor-binding protein, IGFBP. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Cellular communication network factor 2 — has part(s) (P527): Glycoprotein hormone subunit beta. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Cellular communication network factor 2 — has part(s) (P527): Thrombospondin type-1 (TSP1) repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Cellular communication network factor 2 — has part(s) (P527): VWFC domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Cellular communication network factor 2 — has part(s) (P527): Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Cellular communication network factor 2 — has part(s) (P527): Cystine knot, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Cellular communication network factor 2 — RefSeq protein ID (P637): NP_034347. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Cellular communication network factor 2 — molecular function (P680): insulin-like growth factor binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Cellular communication network factor 2 — molecular function (P680): heparin binding. GOA. Retrieved 2018-01-31. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Cellular communication network factor 2 — molecular function (P680): integrin binding. Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3). Retrieved 2018-01-31. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Cellular communication network factor 2 — molecular function (P680): protein C-terminus binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Cellular communication network factor 2 — molecular function (P680): growth factor activity. GOA. Retrieved 2018-01-31. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Cellular communication network factor 2 — molecular function (P680): fibronectin binding. GOA. Retrieved 2018-01-31. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Cellular communication network factor 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Cellular communication network factor 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cellular-communication-network-factor-2-q14907754.

BibTeX

@misc{4ortxyz_cellular-communication-network-factor-2-q14907754_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Cellular communication network factor 2}}, year = {2026}, url = {https://4ort.xyz/entity/cellular-communication-network-factor-2-q14907754}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Cellular communication network factor 2 — https://4ort.xyz/entity/cellular-communication-network-factor-2-q14907754 (retrieved 2026-05-03)

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