CD3e molecule
mammalian protein found in Homo sapiens
Facts
8 properties- Instance of
- protein
- Part of
- CD3 protein, epsilon/gamma/delta subunit, Immunoglobulin-like fold, Immunoglobulin-like domain superfamily, Immunoglobulin subtype 2, protein family, Phosphorylated immunoreceptor signalling ITAM, protein family[2][3][4][5][6]
- Biological process
- regulation of apoptotic process, G protein-coupled receptor signaling pathway, positive regulation of calcium-mediated signaling, negative regulation of smoothened signaling pathway, T cell differentiation in thymus, response to nutrient, transmembrane receptor protein tyrosine kinase signaling pathway, immune system process, T cell costimulation, positive regulation of interferon-gamma production, signal complex assembly, negative regulation of gene expression, positive regulation of interleukin-4 production, negative thymic T cell selection, cell surface receptor signaling pathway, positive regulation of gene expression, positive regulation of T cell anergy, positive regulation of T cell activation, positive regulation of T cell proliferation, positive regulation of alpha-beta T cell proliferation, positive regulation of peptidyl-tyrosine phosphorylation, regulation of immune response, apoptotic signaling pathway, lymphocyte activation, T cell receptor signaling pathway, T cell activation, protein homooligomerization, dendrite development, cerebellum development, adaptive immune response, protein-containing complex assembly, positive regulation of cell-matrix adhesion, cell surface receptor signaling pathway, T cell differentiation, T cell costimulation, positive regulation of cell-cell adhesion mediated by integrin, positive thymic T cell selection
- Cell component
- integral component of membrane, membrane, cell-cell junction, alpha-beta T cell receptor complex, plasma membrane, integral component of plasma membrane, T cell receptor complex, immunological synapse, external side of plasma membrane, dendritic spine, cell body, external side of plasma membrane, alpha-beta T cell receptor complex[19]
- Encoded by
- CD3E
- Found in taxon
- Homo sapiens
- Molecular function
- SH3 domain binding, signal transducer activity, protein binding, protein heterodimerization activity, signaling receptor complex adaptor activity, T cell receptor binding, protein kinase binding, transmembrane signaling receptor activity, protein homodimerization activity, transmembrane signaling receptor activity[9][10][11][12][13][14][15][16][17][18]
🏷️ Also known as
en CD3E
en CD3e antigen, epsilon polypeptide (TiT3 complex)
en CD3e molecule
en CD3e molecule, epsilon (CD3-TCR complex)
en CD3-epsilon
en T-cell antigen receptor complex, epsilon subunit of T3
en T-cell surface antigen T3/Leu-4 epsilon chain
en T-cell surface glycoprotein CD3 epsilon chain
🔖 Identifiers · 5
- Ensembl protein ID
- ENSP00000354566, ENSP00000433975
- RefSeq protein ID
- NP_000724
- Transporter Classification Database ID
- 8.A.128.1.10
- UniProt protein ID
- P07766
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Summary
CD3e molecule is a protein[1].