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CD3d molecule

mammalian protein found in Homo sapiens
Protein Protein Q21114003

Facts

8 properties
Instance of
protein
Part of
T-cell surface glycoprotein CD3 delta chain, Immunoglobulin-like fold, Immunoglobulin-like domain superfamily, CD3 gamma/delta subunit, Ig-like domain, protein family, Phosphorylated immunoreceptor signalling ITAM, protein family[2][3][4][5][6]
Biological process
positive regulation of transcription by RNA polymerase II, regulation of immune response, T cell receptor signaling pathway, T cell differentiation, positive thymic T cell selection, cell surface receptor signaling pathway, membrane organization, protein homooligomerization, adaptive immune response, immune system process, cell surface receptor signaling pathway, T cell differentiation, positive thymic T cell selection
Cell component
membrane, cytoplasm, alpha-beta T cell receptor complex, integral component of membrane, T cell receptor complex, clathrin-coated vesicle membrane, plasma membrane, external side of plasma membrane, alpha-beta T cell receptor complex[14][15][16][17][18][19][20][21]
Encoded by
CD3D
Found in taxon
Homo sapiens
Has part(s)
CD3 gamma/delta subunit, Ig-like domain, Phosphorylated immunoreceptor signalling ITAM[7][8]
Molecular function
transcription coactivator activity, protein heterodimerization activity, transmembrane signaling receptor activity, protein homodimerization activity, transmembrane signaling receptor activity[9][10][11][12][13]
🏷️ Also known as
en CD3 antigen, delta subunit en CD3D en CD3d antigen, delta polypeptide (TiT3 complex) en CD3 delta en CD3d molecule en CD3d molecule, delta (CD3-TCR complex) en OKT3, delta chain en T-cell receptor T3 delta chain en T-cell surface glycoprotein CD3 delta chain
🔖 Identifiers · 4
Ensembl protein ID
ENSP00000300692, ENSP00000376622, ENSP00000434794, ENSP00000437335
PDB structure ID
1XIW
RefSeq protein ID
NP_000723, NP_001035741
UniProt protein ID
P04234

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Summary

CD3d molecule is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . wikidata.org.
  5. [6] ↑ . wikidata.org.
  6. [7] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . Murine and human T-lymphocyte GATA-3 factors mediate transcription through a cis-regulatory element within the human T-cell receptor delta gene enhancer. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . Homooligomerization of the cytoplasmic domain of the T cell receptor zeta chain and of other proteins containing the immunoreceptor tyrosine-based activation motif. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . Cloning of a novel cell type from human fetal liver expressing cytoplasmic CD3 delta and epsilon but not membrane CD3. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . Assembly of the TCR/CD3 complex: CD3ε/δ and CD3ε/γ dimers associate indistinctly with both TCRα and TCRβ chains. Evidence for a double TCR heterodimer model. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). CD3d molecule. Retrieved May 3, 2026, from https://4ort.xyz/entity/cd3d-molecule
MLA “CD3d molecule.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/cd3d-molecule.
BibTeX @misc{4ortxyz_cd3d-molecule_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CD3d molecule}}, year = {2026}, url = {https://4ort.xyz/entity/cd3d-molecule}, note = {Accessed: 2026-05-03}}
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