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CD27 molecule

mammalian protein found in Homo sapiens
Protein protein Q2805224

Facts

9 properties
Instance of
protein
Part of
Tumour necrosis factor receptor 7, TNFR/NGFR cysteine-rich region, protein family, Tumour necrosis factor receptor 7, N-terminal domain, protein family[2][3][4]
Biological process
negative regulation of apoptotic process, response to lipopolysaccharide, response to ethanol, negative regulation of T cell apoptotic process, extrinsic apoptotic signaling pathway, regulation of cell population proliferation, cell surface receptor signaling pathway, apoptotic process, tumor necrosis factor-mediated signaling pathway, immunoglobulin mediated immune response, positive regulation of JNK cascade, inflammatory response, immune response, negative regulation of cysteine-type endopeptidase activity involved in apoptotic process, positive regulation of B cell differentiation, positive regulation of T cell differentiation, multicellular organism development, positive regulation of NIK/NF-kappaB signaling, response to ethanol, positive regulation of JNK cascade, negative regulation of T cell apoptotic process, extrinsic apoptotic signaling pathway, negative regulation of apoptotic process
Cell component
extracellular region, integral component of membrane, integral component of plasma membrane, membrane, cell surface, plasma membrane, external side of plasma membrane, integral component of plasma membrane, external side of plasma membrane[13][14]
Encoded by
CD27
Found in taxon
Homo sapiens
Has part(s)
TNFR/NGFR cysteine-rich region, Tumour necrosis factor receptor 7, N-terminal[5][6]
Has parts
TNFR/NGFR cysteine-rich region, Tumour necrosis factor receptor 7, N-terminal
Molecular function
tumor necrosis factor-activated receptor activity, cysteine-type endopeptidase inhibitor activity involved in apoptotic process, protein binding, transmembrane signaling receptor activity, protein binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process[7][8][9][10][11][12]
🏷️ Also known as
en Tumor necrosis factor receptor superfamily member 7 en CD27 en CD27 antigen en CD27L receptor en CD27 molecule en T14 en T-cell activation antigen CD27 en T cell activation antigen S152 en tumor necrosis factor receptor superfamily, member 7 de CD27-Antigen it Recettore del fattore di necrosi tumorale 7 it TNFRSF7 it Tp55
🔖 Identifiers · 8
Ensembl protein ID
ENSP00000266557
Exact match
identifiers.org, purl.uniprot.org, www.ncbi.nlm.nih.gov
Freebase ID
/m/02rqrm4
MeSH descriptor ID
D018127
MeSH tree code
D12.776.543.750.705.852.760.048, D23.050.301.264.894.127, D23.101.100.894.127
RefSeq protein ID
NP_001233, XP_011519344, XP_016875721, XP_016875722, XP_016875723
UMLS CUI
C0054949
UniProt protein ID
P26842

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🔗 Connections
Biological process 2
apoptotic process, immune response
Molecular function 2
protein binding, protein binding
Cell component 1
plasma membrane
Found in taxon 1
Homo sapiens
Instance of 1
protein
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Summary

CD27 molecule is a protein[1].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [3] ↑ . wikidata.org.
  3. [4] ↑ . wikidata.org.
  4. [5] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] ↑ . CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . CD27 synergizes with CD40 to induce IgM, IgG, and IgA antibody responses of peripheral blood B cells in the presence of IL-2 and IL-10. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . CD27 and CD40 inhibit p53-independent mitochondrial pathways in apoptosis of B cells induced by B cell receptor ligation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . High levels of serum soluble CD27 correlated with renal dysfunction. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). CD27 molecule. Retrieved November 8, 2026, from https://4ort.xyz/entity/cd27-molecule
MLA “CD27 molecule.” 4ort.xyz Knowledge Graph, 4ort.xyz, 8 Nov. 2026, https://4ort.xyz/entity/cd27-molecule.
BibTeX @misc{4ortxyz_cd27-molecule_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CD27 molecule}}, year = {2026}, url = {https://4ort.xyz/entity/cd27-molecule}, note = {Accessed: 2026-11-08}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): CD27 molecule — https://4ort.xyz/entity/cd27-molecule (retrieved 2026-11-08)

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