CCAAT/enhancer binding protein (C/EBP), alpha

mammalian protein found in Mus musculus

Protein protein Q21499243

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CCAAT/enhancer binding protein (C/EBP), alpha

Summary

CCAAT/enhancer binding protein (C/EBP), alpha is a protein^[1].

Key Facts

CCAAT/enhancer binding protein (C/EBP), alpha's instance of is recorded as protein^[2].
CCAAT/enhancer binding protein (C/EBP), alpha's subclass of is recorded as protein^[3].
CCAAT/enhancer binding protein (C/EBP), alpha's UniProt protein ID is recorded as P53566^[4].
CCAAT/enhancer binding protein (C/EBP), alpha's part of is recorded as CCAAT/enhancer-binding protein, chordates^[5].
CCAAT/enhancer binding protein (C/EBP), alpha's part of is recorded as Basic-leucine zipper domain, protein family^[6].
CCAAT/enhancer binding protein (C/EBP), alpha's has part is recorded as Basic-leucine zipper domain^[7].
CCAAT/enhancer binding protein (C/EBP), alpha's RefSeq protein ID is recorded as NP_001274443^[8].
CCAAT/enhancer binding protein (C/EBP), alpha's RefSeq protein ID is recorded as NP_001274444^[9].
CCAAT/enhancer binding protein (C/EBP), alpha's RefSeq protein ID is recorded as NP_001274450^[10].
CCAAT/enhancer binding protein (C/EBP), alpha's RefSeq protein ID is recorded as NP_001274452^[11].
CCAAT/enhancer binding protein (C/EBP), alpha's RefSeq protein ID is recorded as NP_031704^[12].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[13].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as DNA-binding transcription factor activity^[14].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as transcription coactivator activity^[15].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as transcription factor binding^[16].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as kinase binding^[17].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as protein binding^[18].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding^[19].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding^[20].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[21].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as DNA binding^[22].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as protein domain specific binding^[23].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as protein homodimerization activity^[24].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as histone deacetylase binding^[25].
CCAAT/enhancer binding protein (C/EBP), alpha's molecular function is recorded as sequence-specific DNA binding^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of CCAAT/enhancer-binding protein, chordates, Basic-leucine zipper domain, protein family

Properties

Biological process Notch signaling pathway, myeloid cell differentiation, cellular response to lithium ion, glucose homeostasis, lung development, cytokine-mediated signaling pathway, urea cycle, regulation of transcription by RNA polymerase II, cellular response to organic cyclic compound, mitochondrion organization, embryonic placenta development, cholesterol metabolic process, negative regulation of transcription by RNA polymerase II, negative regulation of cell cycle, cell maturation, transcription, DNA-templated, macrophage differentiation, multicellular organism development, positive regulation of transcription, DNA-templated, positive regulation of osteoblast differentiation, granulocyte differentiation, regulation of cell population proliferation, brown fat cell differentiation, lipid homeostasis, white fat cell differentiation, inner ear development, liver development, positive regulation of transcription by RNA polymerase III, positive regulation of transcription by RNA polymerase II, negative regulation of cell population proliferation, cellular response to tumor necrosis factor, transcription by RNA polymerase II, transcription by RNA polymerase I, positive regulation of DNA-templated transcription, initiation, regulation of transcription, DNA-templated, fat cell differentiation, positive regulation of fat cell differentiation, negative regulation of transcription, DNA-templated, transcription by RNA polymerase I, positive regulation of macrophage activation, positive regulation of inflammatory response, interleukin-6-mediated signaling pathway, interleukin-6-mediated signaling pathway

Cell component RNA polymerase II transcription regulator complex, nucleus, nucleolus, nucleoplasm, intracellular membrane-bounded organelle, transcription regulator complex, nuclear matrix, protein-containing complex, Rb-E2F complex, CHOP-C/EBP complex, nucleolus, transcription regulator complex

Encoded by Cebpa

Found in taxon house mouse

Has part(s) Basic-leucine zipper domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription factor activity, transcription coactivator activity, transcription factor binding, kinase binding, protein binding, transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA binding, protein domain specific binding, protein homodimerization activity, histone deacetylase binding, sequence-specific DNA binding, protein-containing complex binding, protein heterodimerization activity, HMG box domain binding, DNA-binding transcription factor activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSMUSP00000096129, ENSMUSP00000145942

Refseq protein id NP_001274443, NP_001274444, NP_001274450, NP_001274452, NP_031704

Uniprot protein id P53566

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — UniProt protein ID (P352): P53566. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — part of (P361): CCAAT/enhancer-binding protein, chordates. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — part of (P361): Basic-leucine zipper domain, protein family. wikidata.org.
[7] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — has part(s) (P527): Basic-leucine zipper domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — RefSeq protein ID (P637): NP_001274443. Q20641742. Retrieved 2022-03-20. wikidata.org.
[9] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — RefSeq protein ID (P637): NP_001274444. Q20641742. Retrieved 2022-03-20. wikidata.org.
[10] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — RefSeq protein ID (P637): NP_001274450. Q20641742. Retrieved 2022-03-20. wikidata.org.
[11] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — RefSeq protein ID (P637): NP_001274452. Q20641742. Retrieved 2022-03-20. wikidata.org.
[12] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — RefSeq protein ID (P637): NP_031704. Q20641742. Retrieved 2022-03-20. wikidata.org.
[13] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): DNA-binding transcription factor activity. Signal transducers and activators of transcription 3 augments the transcriptional activity of CCAAT/enhancer-binding protein alpha in granulocyte colony-stimulating factor signaling pathway. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): transcription coactivator activity. SIRT1 regulates adiponectin gene expression through Foxo1-C/enhancer-binding protein alpha transcriptional complex. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): transcription factor binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): kinase binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): protein binding. Liver tumors escape negative control of proliferation via PI3K/Akt-mediated block of C/EBP alpha growth inhibitory activity. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding. Identification and characterization of a 315-base pair enhancer, located more than 55 kilobases 5' of the apolipoprotein B gene, that confers expression in the intestine. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): RNA polymerase II cis-regulatory region sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): protein domain specific binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): protein homodimerization activity. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): histone deacetylase binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ CCAAT/enhancer binding protein (C/EBP), alpha — molecular function (P680): sequence-specific DNA binding. GOA. Retrieved 2019-02-14. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ CCAAT/enhancer binding protein (C/EBP), alpha is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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MLA

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BibTeX

@misc{4ortxyz_ccaat-enhancer-binding-protein-c-ebp-alpha_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{CCAAT/enhancer binding protein (C/EBP), alpha}}, year = {2026}, url = {https://4ort.xyz/entity/ccaat-enhancer-binding-protein-c-ebp-alpha}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): CCAAT/enhancer binding protein (C/EBP), alpha — https://4ort.xyz/entity/ccaat-enhancer-binding-protein-c-ebp-alpha (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ccaat-enhancer-binding-protein-c-ebp-alpha · Last refreshed: May 3, 2026