Cathepsin S
mammalian protein found in Homo sapiens
Facts
8 properties- Instance of
- protein
- Biological process
- positive regulation of cation channel activity, antigen processing and presentation, adaptive immune response, antigen processing and presentation of exogenous peptide antigen via MHC class II, protein processing, extracellular matrix disassembly, proteolysis, toll-like receptor signaling pathway, antigen processing and presentation of peptide antigen, immune response, cellular response to thyroid hormone stimulus, collagen catabolic process, proteolysis involved in cellular protein catabolic process, basement membrane disassembly, response to acidic pH, neutrophil degranulation, proteolysis involved in cellular protein catabolic process[22][23][24][25][26][27][28][29][30][31][32][33][34][35]
- Cell component
- intracellular membrane-bounded organelle, extracellular region, endolysosome lumen, lysosomal lumen, lysosome, extracellular space, tertiary granule lumen, ficolin-1-rich granule lumen, extracellular space, lysosome, collagen-containing extracellular matrix, late endosome[12][13][14][15][16][17][18][19][20][21]
- EC enzyme number
- 3.4.22.27[2]
- Found in taxon
- Homo sapiens[37]
- Molecular function
- fibronectin binding, cysteine-type peptidase activity, collagen binding, peptidase activity, cysteine-type endopeptidase activity, laminin binding, hydrolase activity, proteoglycan binding, serine-type endopeptidase activity, cysteine-type endopeptidase activity[3][4][5][6][7][8][9][10][11]
- Physically interacts with
- odanacatib[1]
🏷️ Also known as
en Cathepsin S
en CTSS
ru Катепсин C
🔖 Identifiers · 4
- Ensembl protein ID
- ENSP00000357981, ENSP00000408414, ENSP00000475176, ENSP00000475557, ENSP00000475812
- PDB structure ID
- 1GLO, 1MS6, 1NPZ, 1NQC, 2C0Y, 2F1G, 2FQ9, 2FRA, 2FRQ, 2FT2, 2FUD, 2FYE, 2G6D, 2G7Y, 2H7J, 2HH5, 2HHN, 2HXZ, 2OP3, 2R9M, 2R9N, 2R9O, 3IEJ, 3KWN, 3MPE, 3MPF, 3N3G, 3N4C, 3OVX, 4P6E, 4P6G
- RefSeq protein ID
- NP_001186668, NP_004070
- UniProt protein ID
- P25774
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