Catechol-O-methyltransferase

mammalian protein found in Homo sapiens
Protein protein Q418781
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Catechol-O-methyltransferase

Summary

Catechol-O-methyltransferase is a protein[1].

Key Facts

  • Catechol-O-methyltransferase's instance of is recorded as protein[2].
  • Catechol-O-methyltransferase's physically interacts with is recorded as entacapone[3].
  • Catechol-O-methyltransferase's physically interacts with is recorded as tolcapone[4].
  • Catechol-O-methyltransferase's physically interacts with is recorded as Viroporin 3a[5].
  • Catechol-O-methyltransferase is part of catechol O-methyltransferase, eukaryotic[6].
  • Catechol-O-methyltransferase is part of S-adenosyl-L-methionine-dependent methyltransferase[7].
  • Catechol-O-methyltransferase's Commons category is recorded as Catechol O-methyltransferase, COMT[8].
  • Catechol-O-methyltransferase's molecular function is recorded as transferase activity[9].
  • Catechol-O-methyltransferase's molecular function is recorded as O-methyltransferase activity[10].
  • Catechol-O-methyltransferase's molecular function is recorded as metal ion binding[11].
  • Catechol-O-methyltransferase's molecular function is recorded as protein binding[12].
  • Catechol-O-methyltransferase's molecular function is recorded as magnesium ion binding[13].
  • Catechol-O-methyltransferase's molecular function is recorded as catechol O-methyltransferase activity[14].
  • Catechol-O-methyltransferase's molecular function is recorded as methyltransferase activity[15].
  • Catechol-O-methyltransferase's molecular function is recorded as L-dopa O-methyltransferase activity[16].
  • Catechol-O-methyltransferase's molecular function is recorded as orcinol O-methyltransferase activity[17].
  • Catechol-O-methyltransferase's molecular function is recorded as catechol O-methyltransferase activity[18].
  • Catechol-O-methyltransferase's cell component is recorded as cytoplasm[19].
  • Catechol-O-methyltransferase's cell component is recorded as integral component of membrane[20].
  • Catechol-O-methyltransferase's cell component is recorded as cell body[21].
  • Catechol-O-methyltransferase's cell component is recorded as cytosol[22].
  • Catechol-O-methyltransferase's cell component is recorded as postsynaptic membrane[23].
  • Catechol-O-methyltransferase's cell component is recorded as membrane[24].
  • Catechol-O-methyltransferase's cell component is recorded as plasma membrane[25].
  • Catechol-O-methyltransferase's cell component is recorded as dendritic spine[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [5] . BioGRID. Retrieved . thebiogrid.org. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . Cloning and Characterization of Human Placental Catechol--Methyltransferase cDNA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . An empirical framework for binary interactome mapping. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Catechol-O-methyltransferase. Retrieved May 3, 2026, from https://4ort.xyz/entity/catechol-o-methyltransferase-q418781
MLA “Catechol-O-methyltransferase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/catechol-o-methyltransferase-q418781.
BibTeX @misc{4ortxyz_catechol-o-methyltransferase-q418781_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Catechol-O-methyltransferase}}, year = {2026}, url = {https://4ort.xyz/entity/catechol-o-methyltransferase-q418781}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Catechol-O-methyltransferase — https://4ort.xyz/entity/catechol-o-methyltransferase-q418781 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4w ago · Boghog · 2026-07-23 view diff on Wikidata ↗
    Uniprot protein id P21964
    Exact match http://purl.uniprot.org/uniprot/P21964
    Imported from
    Ensembl protein id ENSP00000416778, ENSP00000354511, ENSP00000384654 +6
    + 16 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.1.1.6, [[:toollabs:quickstatements/#/batch/261446|batch #261446]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.