Calcium channel, voltage-dependent, L type, alpha 1C subunit

mammalian protein found in Mus musculus

Protein protein Q14905748

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Calcium channel, voltage-dependent, L type, alpha 1C subunit

Summary

Calcium channel, voltage-dependent, L type, alpha 1C subunit is a protein^[1].

Key Facts

Calcium channel, voltage-dependent, L type, alpha 1C subunit's instance of is recorded as protein^[2].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's physically interacts with is recorded as isradipine^[3].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's physically interacts with is recorded as (RS)-nisoldipine^[4].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's UniProt protein ID is recorded as Q01815^[5].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Voltage-dependent calcium channel, L-type, alpha-1C subunit^[6].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Voltage-dependent channel domain superfamily^[7].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as voltage-gated ion channel^[8].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Voltage-gated calcium channel subunit alpha, C-terminal domain, protein family^[9].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Ion transport domain, protein family^[10].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, protein family^[11].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's part of is recorded as Voltage-dependent L-type calcium channel, IQ-associated domain, protein family^[12].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's has part is recorded as Ion transport domain^[13].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's has part is recorded as Voltage-gated calcium channel subunit alpha, C-terminal^[14].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's has part is recorded as Voltage-dependent L-type calcium channel, IQ-associated domain^[15].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's has part is recorded as Voltage-dependent calcium channel, alpha-1 subunit, IQ domain^[16].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001153005^[17].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001153006^[18].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001153007^[19].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242926^[20].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242927^[21].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242928^[22].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242929^[23].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242930^[24].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001242931^[25].
Calcium channel, voltage-dependent, L type, alpha 1C subunit's RefSeq protein ID is recorded as NP_001277264^[26].

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Quick Facts

Instance of protein

Part of Voltage-dependent calcium channel, L-type, alpha-1C subunit, Voltage-dependent channel domain superfamily, voltage-gated ion channel, Voltage-gated calcium channel subunit alpha, C-terminal domain, protein family, Ion transport domain, protein family, Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, protein family, Voltage-dependent L-type calcium channel, IQ-associated domain, protein family

Properties

Biological process visual learning, smooth muscle contraction, membrane depolarization during action potential, glucose homeostasis, positive regulation of cytosolic calcium ion concentration, regulation of ion transmembrane transport, cellular calcium ion homeostasis, insulin secretion, ion transport, regulation of blood pressure, regulation of vasoconstriction, cardiac conduction, growth hormone secretion, calcium ion transmembrane transport, transmembrane transport, transport, smooth muscle contraction involved in micturition, regulation of organ growth, calcium-ion regulated exocytosis, adult walking behavior, chemical synaptic transmission, calcium ion transport, regulation of heart rate by cardiac conduction, membrane depolarization during cardiac muscle cell action potential, calcium ion transmembrane transport via high voltage-gated calcium channel, cardiac muscle cell action potential involved in contraction, immune system development, regulation of ventricular cardiac muscle cell action potential, membrane depolarization during atrial cardiac muscle cell action potential, membrane depolarization during AV node cell action potential, camera-type eye development, development of the heart, embryonic forelimb morphogenesis, calcium ion transport, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, positive regulation of adenylate cyclase activity, regulation of postsynaptic membrane potential, calcium ion transport into cytosol, calcium ion import, positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

Cell component cytoplasm, integral component of membrane, postsynaptic density, caveolar macromolecular signaling complex, plasma membrane, dendritic shaft, membrane, T-tubule, L-type voltage-gated calcium channel complex, voltage-gated calcium channel complex, soma, Z discdkac, integral component of plasma membrane, cell surface, postsynaptic density, membrane, Z discdkac, cell junction, T-tubule, dendrite, protein-containing complex, sarcolemma, presynaptic membrane, cell projection, soma, perikaryon, synapse, postsynaptic membrane, glutamatergic synapse, integral component of postsynaptic membrane, integral component of presynaptic membrane, T-tubule

Encoded by Cacna1c

Found in taxon house mouse

Has part(s) Ion transport domain, Voltage-gated calcium channel subunit alpha, C-terminal, Voltage-dependent L-type calcium channel, IQ-associated domain, Voltage-dependent calcium channel, alpha-1 subunit, IQ domain

Imported from wholeness_audit_2026-05-02

Molecular function voltage-gated calcium channel activity, calcium channel activity, metal ion binding, voltage-gated ion channel activity, calmodulin binding, ion channel activity, protein binding, enzyme binding, high voltage-gated calcium channel activity, voltage-gated calcium channel activity involved in AV node cell action potential, voltage-gated calcium channel activity involved in cardiac muscle cell action potential, alpha-actinin binding, voltage-gated calcium channel activity, calmodulin binding, protein domain specific binding, translation initiation factor binding, transmembrane transporter binding, protein phosphatase 2A binding, voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential

Physically interacts with isradipine, (RS)-nisoldipine

External References (4)

Ensembl protein id ENSMUSP00000075021, ENSMUSP00000077433, ENSMUSP00000108444, ENSMUSP00000108410, ENSMUSP00000108413, ENSMUSP00000139855, ENSMUSP00000139981, ENSMUSP00000140056, ENSMUSP00000140220, ENSMUSP00000140341, ENSMUSP00000140415, ENSMUSP00000140693, ENSMUSP00000140833, ENSMUSP00000140886, ENSMUSP00000140920, ENSMUSP00000140961, ENSMUSP00000141015, ENSMUSP00000141033, ENSMUSP00000151391, ENSMUSP00000151458, ENSMUSP00000151462, ENSMUSP00000151863, ENSMUSP00000159252

Refseq protein id NP_001153005, NP_001153006, NP_001153007, NP_001242926, NP_001242927, NP_001242928, NP_001242929, NP_001242930, NP_001242931, NP_001277264, NP_033911, XP_006505478, XP_006505481, XP_006505489, XP_006505490, XP_006505493, XP_006505495, XP_006505497, XP_006505498, XP_006505499, XP_006505500, XP_006505501, XP_006505502, XP_006505503, XP_006505504, XP_006505505, XP_006505506, XP_011239477, XP_011239478, XP_011239486, XP_011239487, XP_011239488, XP_011239489, XP_011239494, XP_011239495, XP_017176847, XP_017176851, XP_030110985, XP_030110986, XP_036021662, XP_036021663, XP_036021664, XP_036021665, XP_036021666, XP_036021667, XP_036021668, XP_036021669, XP_036021670, XP_036021671, XP_036021672, XP_036021673, XP_036021674, XP_036021675

Transporter classification database id 1.A.1.11.6

Uniprot protein id Q01815

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — physically interacts with (P129): isradipine. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — physically interacts with (P129): (RS)-nisoldipine. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[5] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — UniProt protein ID (P352): Q01815. Q905695. Retrieved 2022-05-25. wikidata.org.
[6] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Voltage-dependent calcium channel, L-type, alpha-1C subunit. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Voltage-dependent channel domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): voltage-gated ion channel. Retrieved 2019-10-02. wikidata.org.
[9] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Voltage-gated calcium channel subunit alpha, C-terminal domain, protein family. wikidata.org.
[10] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Ion transport domain, protein family. wikidata.org.
[11] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Voltage-dependent calcium channel, alpha-1 subunit, IQ domain, protein family. wikidata.org.
[12] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — part of (P361): Voltage-dependent L-type calcium channel, IQ-associated domain, protein family. wikidata.org.
[13] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — has part(s) (P527): Ion transport domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — has part(s) (P527): Voltage-gated calcium channel subunit alpha, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — has part(s) (P527): Voltage-dependent L-type calcium channel, IQ-associated domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — has part(s) (P527): Voltage-dependent calcium channel, alpha-1 subunit, IQ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001153005. Q20641742. Retrieved 2022-03-20. wikidata.org.
[18] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001153006. Q20641742. Retrieved 2022-03-20. wikidata.org.
[19] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001153007. Q20641742. Retrieved 2022-03-20. wikidata.org.
[20] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242926. Q20641742. Retrieved 2022-03-20. wikidata.org.
[21] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242927. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242928. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242929. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242930. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001242931. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit — RefSeq protein ID (P637): NP_001277264. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ Calcium channel, voltage-dependent, L type, alpha 1C subunit is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Calcium channel, voltage-dependent, L type, alpha 1C subunit. Retrieved May 3, 2026, from https://4ort.xyz/entity/calcium-channel-voltage-dependent-l-type-alpha-1c-subunit

MLA

“Calcium channel, voltage-dependent, L type, alpha 1C subunit.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/calcium-channel-voltage-dependent-l-type-alpha-1c-subunit.

BibTeX

@misc{4ortxyz_calcium-channel-voltage-dependent-l-type-alpha-1c-subunit_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Calcium channel, voltage-dependent, L type, alpha 1C subunit}}, year = {2026}, url = {https://4ort.xyz/entity/calcium-channel-voltage-dependent-l-type-alpha-1c-subunit}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Calcium channel, voltage-dependent, L type, alpha 1C subunit — https://4ort.xyz/entity/calcium-channel-voltage-dependent-l-type-alpha-1c-subunit (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/calcium-channel-voltage-dependent-l-type-alpha-1c-subunit · Last refreshed: May 3, 2026