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C9orf72-SMCR8 complex subunit

mammalian protein found in Homo sapiens
Protein protein Q21102398
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C9orf72-SMCR8 complex subunit

Summary

C9orf72-SMCR8 complex subunit is a protein[1].

Key Facts

  • C9orf72-SMCR8 complex subunit's instance of is recorded as protein[2].
  • C9orf72-SMCR8 complex subunit's UniProt protein ID is recorded as Q96LT7[3].
  • C9orf72-SMCR8 complex subunit's part of is recorded as guanine nucleotide exchange C9orf72[4].
  • C9orf72-SMCR8 complex subunit's RefSeq protein ID is recorded as NP_001242983[5].
  • C9orf72-SMCR8 complex subunit's RefSeq protein ID is recorded as NP_060795[6].
  • C9orf72-SMCR8 complex subunit's RefSeq protein ID is recorded as NP_659442[7].
  • C9orf72-SMCR8 complex subunit's molecular function is recorded as protein binding[8].
  • C9orf72-SMCR8 complex subunit's molecular function is recorded as guanyl-nucleotide exchange factor activity[9].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as autophagosome[10].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as extracellular region[11].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as endosome[12].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as lysosome[13].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as cytoplasmic vesicle[14].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as nucleus[15].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as extracellular space[16].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as guanyl-nucleotide exchange factor complex[17].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as cytoplasm[18].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as Atg1/ULK1 kinase complex[19].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as axonal growth cone[20].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as main axon[21].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as P-body[22].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as membrane[23].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as axon[24].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as dendrite[25].
  • C9orf72-SMCR8 complex subunit's cell component is recorded as growth cone[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] ↑ . Q905695. Retrieved . wikidata.org.
  2. [3] ↑ . Q905695. Retrieved . wikidata.org.
  3. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] ↑ . Q20641742. Retrieved . wikidata.org.
  5. [6] ↑ . Q20641742. Retrieved . wikidata.org.
  6. [7] ↑ . Q20641742. Retrieved . wikidata.org.
  7. [8] ↑ . C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] ↑ . C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] ↑ . Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] ↑ . The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] ↑ . C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] ↑ . C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). C9orf72-SMCR8 complex subunit. Retrieved May 3, 2026, from https://4ort.xyz/entity/c9orf72-smcr8-complex-subunit
MLA “C9orf72-SMCR8 complex subunit.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/c9orf72-smcr8-complex-subunit.
BibTeX @misc{4ortxyz_c9orf72-smcr8-complex-subunit_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{C9orf72-SMCR8 complex subunit}}, year = {2026}, url = {https://4ort.xyz/entity/c9orf72-smcr8-complex-subunit}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): C9orf72-SMCR8 complex subunit — https://4ort.xyz/entity/c9orf72-smcr8-complex-subunit (retrieved 2026-05-03)

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