Bromodomain containing 4

mammalian protein found in Homo sapiens

Protein protein Q21100441

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Bromodomain containing 4

Summary

Bromodomain containing 4 is a protein^[1].

Key Facts

Bromodomain containing 4's instance of is recorded as protein^[2].
Bromodomain containing 4's physically interacts with is recorded as JQ1^[3].
Bromodomain containing 4's physically interacts with is recorded as LY-294002^[4].
Bromodomain containing 4's physically interacts with is recorded as Viroporin 3a^[5].
Bromodomain containing 4's UniProt protein ID is recorded as O60885^[6].
Bromodomain containing 4's part of is recorded as Bromodomain-like superfamily^[7].
Bromodomain containing 4's part of is recorded as NET domain superfamily^[8].
Bromodomain containing 4's part of is recorded as NET domain, protein family^[9].
Bromodomain containing 4's part of is recorded as Bromodomain protein 4, C-terminal domain, protein family^[10].
Bromodomain containing 4's part of is recorded as bromodomain protein family^[11].
Bromodomain containing 4's part of is recorded as Bromodomain, conserved site, protein family^[12].
Bromodomain containing 4's MeSH descriptor ID is recorded as C441289^[13].
Bromodomain containing 4's has part is recorded as Bromodomain, conserved site^[14].
Bromodomain containing 4's has part is recorded as Bromodomain protein 4, C-terminal^[15].
Bromodomain containing 4's has part is recorded as bromodomain^[16].
Bromodomain containing 4's has part is recorded as NET domain^[17].
Bromodomain containing 4's RefSeq protein ID is recorded as NP_001317313^[18].
Bromodomain containing 4's RefSeq protein ID is recorded as NP_055114^[19].
Bromodomain containing 4's RefSeq protein ID is recorded as NP_490597^[20].
Bromodomain containing 4's RefSeq protein ID is recorded as NP_001366220^[21].
Bromodomain containing 4's RefSeq protein ID is recorded as NP_001366221^[22].
Bromodomain containing 4's PDB structure ID is recorded as 2I8N^[23].
Bromodomain containing 4's PDB structure ID is recorded as 2LSP^[24].
Bromodomain containing 4's PDB structure ID is recorded as 2MJV^[25].
Bromodomain containing 4's PDB structure ID is recorded as 2OSS^[26].

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Quick Facts

Instance of protein

Part of Bromodomain-like superfamily, NET domain superfamily, NET domain, protein family, Bromodomain protein 4, C-terminal domain, protein family, bromodomain protein family, Bromodomain, conserved site, protein family

Properties

Biological process chromatin remodeling, regulation of transcription, DNA-templated, negative regulation of DNA damage checkpoint, regulation of transcription involved in G1/S transition of mitotic cell cycle, transcription, DNA-templated, cellular response to DNA damage stimulus, regulation of inflammatory response, positive regulation of I-kappaB kinase/NF-kappaB signaling, positive regulation of G2/M transition of mitotic cell cycle, regulation of phosphorylation of RNA polymerase II C-terminal domain, viral process, positive regulation of transcription elongation from RNA polymerase II promoter, positive regulation of transcription by RNA polymerase II, chromatin organization, protein phosphorylation, cellular response to DNA damage stimulus, positive regulation of transcription, DNA-templated, positive regulation of histone H3-K36 trimethylation

Cell component nucleoplasm, chromosome, condensed nuclear chromosome, nucleus, cytosol, chromosome

Encoded by BRD4

Found in taxon Homo sapiens

Has part(s) Bromodomain, conserved site, Bromodomain protein 4, C-terminal, bromodomain, NET domain

Imported from wholeness_audit_2026-05-02

Molecular function p53 binding, chromatin binding, protein binding, lysine-acetylated histone binding, RNA polymerase II complex binding, RNA polymerase II CTD heptapeptide repeat kinase activity, enzyme binding, RNA polymerase II C-terminal domain binding, P-TEFb complex binding

Physically interacts with JQ1, LY-294002, Viroporin 3a

External References (6)

Ensembl protein id ENSP00000263377, ENSP00000353112, ENSP00000360901, ENSP00000470108, ENSP00000470481, ENSP00000471240, ENSP00000486621

Mesh descriptor id C441289

Pdb structure id 2I8N, 2LSP, 2MJV, 2OSS, 2OUO, 2YEL, 2YEM, 3MXF, 3P5O, 3SVF, 3SVG, 3U5J, 3U5K, 3U5L, 3UVW, 3UVX, 3UVY, 3UW9, 3ZYU, 4A9L, 4BJX, 4BW1, 4BW2, 4BW3, 4BW4, 4C66, 4C67, 4CFK, 4CFL, 4CL9, 4CLB, 4DON, 4E96, 4F3I, 4GPJ, 4HBV, 4HBW, 4HBX, 4HBY, 4HXK, 4HXL, 4HXM, 4HXN, 4HXO, 4HXP, 4HXR, 4HXS, 4IOO, 4IOQ, 4IOR, 4J0R, 4J0S, 4J3I, 4KV1, 4KV4, 4LR6, 4LRG, 4LYI, 4LYS, 4LYW, 4LZR, 4LZS, 4MEN, 4MEO, 4MEP, 4MEQ, 4MR3, 4MR4, 4NQM, 4NR8, 4NUC, 4NUD, 4NUE, 4O70, 4O71, 4O72, 4O74, 4O75, 4O76, 4O77, 4O78, 4O7A, 4O7B, 4O7C, 4O7E, 4O7F, 4OGI, 4OGJ, 4PCE, 4PCI, 4PS5, 4QB3, 4QR3, 4QR4, 4QR5, 4QZS, 4UIX, 4UIZ, 4UYD, 4WIV, 4XY9, 4XYA, 4Z1Q, 4Z1S, 4Z93, 5A5S, 5A85, 5BT4, 5D3T, 5D3S, 5D3H, 5D3J, 5CTL, 4WHW, 5D3R, 4X2I, 5CPE, 5CRZ, 4YH3, 4ZC9, 5EI4, 5D3P, 5CQT, 5D3L, 5EIS, 5CRM, 5D0C, 5EGU, 5CP5, 5D25, 5CY9, 5COI, 5D26, 4YH4, 5CS8, 5ACY, 5DX4, 5D24, 5HM0, 5HLS, 2N3K, 5JWM, 5DLX, 2NCZ, 2NNU, 5DW2, 2ND1, 4ZW1, 5CFW, 2ND0, 5DLZ

Refseq protein id NP_001317313, NP_055114, NP_490597, NP_001366220, NP_001366221

Umls cui C1448198

Uniprot protein id O60885

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Bromodomain containing 4 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Bromodomain containing 4 — physically interacts with (P129): JQ1. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[4] ↑ Bromodomain containing 4 — physically interacts with (P129): LY-294002. IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved 2016-08-17. wikidata.org.
[5] ↑ Bromodomain containing 4 — physically interacts with (P129): Viroporin 3a. BioGRID. Retrieved 2020-04-19. thebiogrid.org. Provenance: wikidata.org.
[6] ↑ Bromodomain containing 4 — UniProt protein ID (P352): O60885. Q905695. Retrieved 2019-11-13. wikidata.org.
[7] ↑ Bromodomain containing 4 — part of (P361): Bromodomain-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Bromodomain containing 4 — part of (P361): NET domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Bromodomain containing 4 — part of (P361): NET domain, protein family. wikidata.org.
[10] ↑ Bromodomain containing 4 — part of (P361): Bromodomain protein 4, C-terminal domain, protein family. wikidata.org.
[11] ↑ Bromodomain containing 4 — part of (P361): bromodomain protein family. wikidata.org.
[12] ↑ Bromodomain containing 4 — part of (P361): Bromodomain, conserved site, protein family. wikidata.org.
[13] ↑ Bromodomain containing 4 — MeSH descriptor ID (P486): C441289. wikidata.org.
[14] ↑ Bromodomain containing 4 — has part(s) (P527): Bromodomain, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Bromodomain containing 4 — has part(s) (P527): Bromodomain protein 4, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Bromodomain containing 4 — has part(s) (P527): bromodomain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Bromodomain containing 4 — has part(s) (P527): NET domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Bromodomain containing 4 — RefSeq protein ID (P637): NP_001317313. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Bromodomain containing 4 — RefSeq protein ID (P637): NP_055114. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Bromodomain containing 4 — RefSeq protein ID (P637): NP_490597. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Bromodomain containing 4 — RefSeq protein ID (P637): NP_001366220. Q20641742. Retrieved 2020-04-04. wikidata.org.
[22] ↑ Bromodomain containing 4 — RefSeq protein ID (P637): NP_001366221. Q20641742. Retrieved 2020-04-04. wikidata.org.
[23] ↑ Bromodomain containing 4 — PDB structure ID (P638): 2I8N. Q905695. Retrieved 2016-08-09. wikidata.org.
[24] ↑ Bromodomain containing 4 — PDB structure ID (P638): 2LSP. Q905695. Retrieved 2016-08-09. wikidata.org.
[25] ↑ Bromodomain containing 4 — PDB structure ID (P638): 2MJV. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Bromodomain containing 4 — PDB structure ID (P638): 2OSS. Q905695. Retrieved 2016-08-09. wikidata.org.

Class ancestry

[1] ↑ Bromodomain containing 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Bromodomain containing 4. Retrieved May 3, 2026, from https://4ort.xyz/entity/bromodomain-containing-4

MLA

“Bromodomain containing 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/bromodomain-containing-4.

BibTeX

@misc{4ortxyz_bromodomain-containing-4_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Bromodomain containing 4}}, year = {2026}, url = {https://4ort.xyz/entity/bromodomain-containing-4}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Bromodomain containing 4 — https://4ort.xyz/entity/bromodomain-containing-4 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/bromodomain-containing-4 · Last refreshed: May 3, 2026