Bloom syndrome, RecQ like helicase

mammalian protein found in Mus musculus

Protein protein Q21433084

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Bloom syndrome, RecQ like helicase

Summary

Bloom syndrome, RecQ like helicase is a protein^[1].

Key Facts

Bloom syndrome, RecQ like helicase's instance of is recorded as protein^[2].
Bloom syndrome, RecQ like helicase's subclass of is recorded as protein^[3].
Bloom syndrome, RecQ like helicase's UniProt protein ID is recorded as O88700^[4].
Bloom syndrome, RecQ like helicase's part of is recorded as DNA helicase, ATP-dependent, RecQ type^[5].
Bloom syndrome, RecQ like helicase's part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[6].
Bloom syndrome, RecQ like helicase's part of is recorded as Winged helix-like DNA-binding domain superfamily^[7].
Bloom syndrome, RecQ like helicase's part of is recorded as winged helix DNA-binding domain superfamily^[8].
Bloom syndrome, RecQ like helicase's part of is recorded as HRDC-like superfamily^[9].
Bloom syndrome, RecQ like helicase's part of is recorded as Helicase superfamily 1/2, ATP-binding domain, protein family^[10].
Bloom syndrome, RecQ like helicase's part of is recorded as ATP-dependent DNA helicase RecQ, zinc-binding domain, protein family^[11].
Bloom syndrome, RecQ like helicase's part of is recorded as Helicase, C-terminal domain, protein family^[12].
Bloom syndrome, RecQ like helicase's part of is recorded as DEAD/DEAH box helicase^[13].
Bloom syndrome, RecQ like helicase's part of is recorded as HRDC domain, protein family^[14].
Bloom syndrome, RecQ like helicase's part of is recorded as RQC domain, protein family^[15].
Bloom syndrome, RecQ like helicase's part of is recorded as Bloom syndrome protein, BDHCT-box associated domain, protein family^[16].
Bloom syndrome, RecQ like helicase's part of is recorded as BDHCT, protein family^[17].
Bloom syndrome, RecQ like helicase's part of is recorded as DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family^[18].
Bloom syndrome, RecQ like helicase's part of is recorded as Bloom syndrome protein, N-terminal domain, protein family^[19].
Bloom syndrome, RecQ like helicase's has part is recorded as DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site^[20].
Bloom syndrome, RecQ like helicase's has part is recorded as RQC domain^[21].
Bloom syndrome, RecQ like helicase's has part is recorded as Helicase superfamily 1/2, ATP-binding domain^[22].
Bloom syndrome, RecQ like helicase's has part is recorded as DEAD/DEAH box helicase domain^[23].
Bloom syndrome, RecQ like helicase's has part is recorded as ATP-dependent DNA helicase RecQ, zinc-binding domain^[24].
Bloom syndrome, RecQ like helicase's has part is recorded as HRDC domain^[25].
Bloom syndrome, RecQ like helicase's has part is recorded as Bloom syndrome protein, N-terminal domain^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of DNA helicase, ATP-dependent, RecQ type, P-loop containing nucleoside triphosphate hydrolase, Winged helix-like DNA-binding domain superfamily, winged helix DNA-binding domain superfamily, HRDC-like superfamily, Helicase superfamily 1/2, ATP-binding domain, protein family, ATP-dependent DNA helicase RecQ, zinc-binding domain, protein family, Helicase, C-terminal domain, protein family, DEAD/DEAH box helicase, HRDC domain, protein family, RQC domain, protein family, Bloom syndrome protein, BDHCT-box associated domain, protein family, BDHCT, protein family, DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family, Bloom syndrome protein, N-terminal domain, protein family

Properties

Biological process DNA recombination, regulation of cyclin-dependent protein serine/threonine kinase activity, DNA double-strand break processing, negative regulation of thymocyte apoptotic process, chromosome organization, positive regulation of transcription, DNA-templated, negative regulation of cell division, cellular response to camptothecin, cell metabolism, positive regulation of alpha-beta T cell proliferation, replication fork processing, negative regulation of DNA recombination, regulation of binding, cellular response to ionizing radiation, alpha-beta T cell differentiation, mitotic G2 DNA damage checkpoint signaling, telomere maintenance, DNA repair, response to X-ray, cellular response to hydroxyurea, positive regulation of double-strand break repair via homologous recombination, replication-born double-strand break repair via sister chromatid exchange, negative regulation of mitotic recombination, DNA replication, DNA duplex unwinding, G-quadruplex DNA unwinding, telomeric D-loop disassembly, protein homooligomerization, regulation of DNA-dependent DNA replication, cellular response to DNA damage stimulus, protein complex oligomerization, regulation of cyclin-dependent protein serine/threonine kinase activity, resolution of meiotic recombination intermediates, double-strand break repair via homologous recombination, DNA synthesis involved in DNA repair, strand displacement, DNA repair, double-strand break repair via nonhomologous end joining, DNA recombination, mitotic G2 DNA damage checkpoint signaling, response to X-ray, meiotic DNA double-strand break processing involved in reciprocal meiotic recombination, replication fork processing, DNA duplex unwinding, negative regulation of apoptotic process, G-quadruplex DNA unwinding, double-strand break repair via synthesis-dependent strand annealing, positive regulation of transcription, DNA-templated, negative regulation of mitotic recombination, alpha-beta T cell differentiation, positive regulation of alpha-beta T cell proliferation, protein complex oligomerization, protein homooligomerization, meiotic chromosome separation, negative regulation of cell division, telomeric D-loop disassembly, negative regulation of thymocyte apoptotic process, resolution of recombination intermediates, cellular response to ionizing radiation, cellular response to hydroxyurea, regulation of DNA-dependent DNA replication, negative regulation of double-strand break repair via single-strand annealing, positive regulation of double-strand break repair via homologous recombination, telomere maintenance, DNA unwinding involved in DNA replication

Cell component PML body, nuclear matrix, male germ cell nucleus, intracellular anatomical structure, nucleoplasm, lateral element, nuclear chromosome, nucleolus, pronucleus, nucleus, telomere, replication fork, cytoplasm, cytosol, nuclear chromosome, telomere, lateral element, nucleus, replication fork, chromosome, nucleolus, cytoplasm, cytosol, nuclear matrix, PML body, pronucleus

Encoded by Blm

Found in taxon house mouse

Has part(s) DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, RQC domain, Helicase superfamily 1/2, ATP-binding domain, DEAD/DEAH box helicase domain, ATP-dependent DNA helicase RecQ, zinc-binding domain, HRDC domain, Bloom syndrome protein, N-terminal domain, Bloom syndrome protein, BDHCT-box associated domain, Helicase, C-terminal, BDHCT

Imported from wholeness_audit_2026-05-02

Molecular function ATP-dependent DNA/DNA annealing activity, nucleotide binding, helicase activity, DNA helicase activity, 3'-5' DNA helicase activity, bubble DNA binding, p53 binding, G-quadruplex DNA binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, ATPase activity, catalytic activity, protein binding, nucleic acid binding, hydrolase activity, DNA helicase activity, Y-form DNA binding, telomeric D-loop binding, 8-hydroxy-2'-deoxyguanosine DNA binding, four-way junction DNA binding, single-stranded DNA binding, ATP binding, four-way junction helicase activity, forked DNA-dependent helicase activity, DNA binding, ATP-dependent activity, acting on DNA, zinc ion binding, protein homodimerization activity, metal ion binding, four-way junction DNA binding, Y-form DNA binding, bubble DNA binding, p53 binding, single-stranded DNA binding, ATP binding, zinc ion binding, ATP-dependent DNA/DNA annealing activity, protein homodimerization activity, 3'-5' DNA helicase activity, forked DNA-dependent helicase activity, telomeric D-loop binding, 8-hydroxy-2'-deoxyguanosine DNA binding, DNA binding

External References (3)

Ensembl protein id ENSMUSP00000080062, ENSMUSP00000127995, ENSMUSP00000145573, ENSMUSP00000146062, ENSMUSP00000146098

Refseq protein id NP_001035992, NP_031576, XP_017177446

Uniprot protein id O88700

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Bloom syndrome, RecQ like helicase — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Bloom syndrome, RecQ like helicase — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Bloom syndrome, RecQ like helicase — UniProt protein ID (P352): O88700. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Bloom syndrome, RecQ like helicase — part of (P361): DNA helicase, ATP-dependent, RecQ type. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Bloom syndrome, RecQ like helicase — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Bloom syndrome, RecQ like helicase — part of (P361): Winged helix-like DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Bloom syndrome, RecQ like helicase — part of (P361): winged helix DNA-binding domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Bloom syndrome, RecQ like helicase — part of (P361): HRDC-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Bloom syndrome, RecQ like helicase — part of (P361): Helicase superfamily 1/2, ATP-binding domain, protein family. wikidata.org.
[11] ↑ Bloom syndrome, RecQ like helicase — part of (P361): ATP-dependent DNA helicase RecQ, zinc-binding domain, protein family. wikidata.org.
[12] ↑ Bloom syndrome, RecQ like helicase — part of (P361): Helicase, C-terminal domain, protein family. wikidata.org.
[13] ↑ Bloom syndrome, RecQ like helicase — part of (P361): DEAD/DEAH box helicase. wikidata.org.
[14] ↑ Bloom syndrome, RecQ like helicase — part of (P361): HRDC domain, protein family. wikidata.org.
[15] ↑ Bloom syndrome, RecQ like helicase — part of (P361): RQC domain, protein family. wikidata.org.
[16] ↑ Bloom syndrome, RecQ like helicase — part of (P361): Bloom syndrome protein, BDHCT-box associated domain, protein family. wikidata.org.
[17] ↑ Bloom syndrome, RecQ like helicase — part of (P361): BDHCT, protein family. wikidata.org.
[18] ↑ Bloom syndrome, RecQ like helicase — part of (P361): DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family. wikidata.org.
[19] ↑ Bloom syndrome, RecQ like helicase — part of (P361): Bloom syndrome protein, N-terminal domain, protein family. wikidata.org.
[20] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): RQC domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): Helicase superfamily 1/2, ATP-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): DEAD/DEAH box helicase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): ATP-dependent DNA helicase RecQ, zinc-binding domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): HRDC domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Bloom syndrome, RecQ like helicase — has part(s) (P527): Bloom syndrome protein, N-terminal domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Bloom syndrome, RecQ like helicase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Bloom syndrome, RecQ like helicase. Retrieved May 3, 2026, from https://4ort.xyz/entity/bloom-syndrome-recq-like-helicase

MLA

“Bloom syndrome, RecQ like helicase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/bloom-syndrome-recq-like-helicase.

BibTeX

@misc{4ortxyz_bloom-syndrome-recq-like-helicase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Bloom syndrome, RecQ like helicase}}, year = {2026}, url = {https://4ort.xyz/entity/bloom-syndrome-recq-like-helicase}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Bloom syndrome, RecQ like helicase — https://4ort.xyz/entity/bloom-syndrome-recq-like-helicase (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/bloom-syndrome-recq-like-helicase · Last refreshed: May 3, 2026