Beta-transducin repeat containing E3 ubiquitin protein ligase

mammalian protein found in Homo sapiens

Protein protein Q21116841

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Summary

Beta-transducin repeat containing E3 ubiquitin protein ligase is a protein^[1].

Key Facts

Beta-transducin repeat containing E3 ubiquitin protein ligase's instance of is recorded as protein^[2].
Beta-transducin repeat containing E3 ubiquitin protein ligase's UniProt protein ID is recorded as Q9Y297^[3].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as WD40/YVTN repeat-like-containing domain superfamily^[4].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as WD40-repeat-containing domain superfamily^[5].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as F-box-like domain superfamily^[6].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as F-box protein^[7].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as D domain of beta-TrCP, protein family^[8].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as WD40 repeat, protein family^[9].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as WD40 repeat, conserved site, protein family^[10].
Beta-transducin repeat containing E3 ubiquitin protein ligase's part of is recorded as G-protein beta WD-40 repeat, protein family^[11].
Beta-transducin repeat containing E3 ubiquitin protein ligase's has part is recorded as WD40 repeat^[12].
Beta-transducin repeat containing E3 ubiquitin protein ligase's has part is recorded as G-protein beta WD-40 repeat^[13].
Beta-transducin repeat containing E3 ubiquitin protein ligase's has part is recorded as F-box domain^[14].
Beta-transducin repeat containing E3 ubiquitin protein ligase's has part is recorded as D domain of beta-TrCP^[15].
Beta-transducin repeat containing E3 ubiquitin protein ligase's has part is recorded as WD40 repeat, conserved site^[16].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as NP_001243785^[17].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as NP_003930^[18].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as NP_378663^[19].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_006718117^[20].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_011538622^[21].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_016872359^[22].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_016872360^[23].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_016872361^[24].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_016872362^[25].
Beta-transducin repeat containing E3 ubiquitin protein ligase's RefSeq protein ID is recorded as XP_016872363^[26].

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Quick Facts

Instance of protein

Part of WD40/YVTN repeat-like-containing domain superfamily, WD40-repeat-containing domain superfamily, F-box-like domain superfamily, F-box protein, D domain of beta-TrCP, protein family, WD40 repeat, protein family, WD40 repeat, conserved site, protein family, G-protein beta WD-40 repeat, protein family

Properties

Biological process cellular response to organic cyclic compound, protein destabilization, regulation of cell cycle, protein catabolic process, G2/M transition of mitotic cell cycle, negative regulation of DNA-binding transcription factor activity, regulation of I-kappaB kinase/NF-kappaB signaling, stress-activated MAPK cascade, negative regulation of transcription, DNA-templated, positive regulation of proteolysis, regulation of proteasomal protein catabolic process, regulation of circadian rhythm, mammary gland epithelial cell proliferation, branching involved in mammary gland duct morphogenesis, negative regulation of smoothened signaling pathway, rhythmic process, NIK/NF-kappaB signaling, signal transduction, ubiquitin-dependent protein catabolic process, regulation of canonical Wnt signaling pathway, protein dephosphorylation, positive regulation of transcription, DNA-templated, protein ubiquitination, positive regulation of circadian rhythm, Wnt signaling pathway, protein polyubiquitination, viral process, post-translational protein modification, SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, interleukin-1-mediated signaling pathway, proteasome-mediated ubiquitin-dependent protein catabolic process, maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA), SCF-dependent proteasomal ubiquitin-dependent protein catabolic process, regulation of mitotic cell cycle phase transition, stimulatory C-type lectin receptor signaling pathway, Fc-epsilon receptor signaling pathway, T cell receptor signaling pathway, protein ubiquitination

Cell component nucleus, cytoplasm, nucleoplasm, cytosol, SCF ubiquitin ligase complex, small-subunit processome, Pwp2p-containing subcomplex of 90S preribosome

Encoded by BTRC

Found in taxon Homo sapiens

Has part(s) WD40 repeat, G-protein beta WD-40 repeat, F-box domain, D domain of beta-TrCP, WD40 repeat, conserved site

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, ligase activity, protein phosphorylated amino acid binding, protein dimerization activity, beta-catenin binding, ubiquitin protein ligase activity, ubiquitin-protein transferase activity, snoRNA binding, ubiquitin-protein transferase activity

External References (4)

Ensembl protein id ENSP00000359206, ENSP00000385339, ENSP00000359202, ENSP00000377088

Pdb structure id 1P22, 2P64

Refseq protein id NP_001243785, NP_003930, NP_378663, XP_006718117, XP_011538622, XP_016872359, XP_016872360, XP_016872361, XP_016872362, XP_016872363, XP_024304014, XP_024304015

Uniprot protein id Q9Y297

🏷️ Also known as

en Beta-transducin repeat containing E3 ubiquitin protein ligase en beta-TrCP1 en BTRC en E3RSIkappaB en epididymis tissue protein Li 2a en F-box and WD-repeat protein 1B en F-box and WD repeats protein beta-TrCP en F-box/WD repeat-containing protein 1A en pIkappaBalpha-E3 receptor subunit

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — UniProt protein ID (P352): Q9Y297. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): WD40/YVTN repeat-like-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): WD40-repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): F-box-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): F-box protein. wikidata.org.
[8] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): D domain of beta-TrCP, protein family. wikidata.org.
[9] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): WD40 repeat, protein family. wikidata.org.
[10] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): WD40 repeat, conserved site, protein family. wikidata.org.
[11] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — part of (P361): G-protein beta WD-40 repeat, protein family. wikidata.org.
[12] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — has part(s) (P527): WD40 repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — has part(s) (P527): G-protein beta WD-40 repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — has part(s) (P527): F-box domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — has part(s) (P527): D domain of beta-TrCP. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — has part(s) (P527): WD40 repeat, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): NP_001243785. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): NP_003930. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): NP_378663. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_006718117. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_011538622. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_016872359. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_016872360. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_016872361. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_016872362. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase — RefSeq protein ID (P637): XP_016872363. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Beta-transducin repeat containing E3 ubiquitin protein ligase is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Beta-transducin repeat containing E3 ubiquitin protein ligase. Retrieved May 3, 2026, from https://4ort.xyz/entity/beta-transducin-repeat-containing-e3-ubiquitin-protein-ligase

MLA

“Beta-transducin repeat containing E3 ubiquitin protein ligase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/beta-transducin-repeat-containing-e3-ubiquitin-protein-ligase.

BibTeX

@misc{4ortxyz_beta-transducin-repeat-containing-e3-ubiquitin-protein-ligase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Beta-transducin repeat containing E3 ubiquitin protein ligase}}, year = {2026}, url = {https://4ort.xyz/entity/beta-transducin-repeat-containing-e3-ubiquitin-protein-ligase}, note = {Accessed: 2026-05-03}}

LLM prompt

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