Baculoviral IAP repeat containing 2

mammalian protein found in Homo sapiens
Protein protein Q21111704
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Summary

Baculoviral IAP repeat containing 2 is a protein[1]. It is known by 17 alternative names across languages and contexts.[2]

Key Facts

  • Part of: Death-like domain superfamily[3], Zinc finger, RING-type, protein family[4], CARD domain, protein family[5], BIR repeat domain, protein family[6]
  • Commons category: Cellular Inhibitor of Apoptosis Protein 1[7]
  • Has part(s): Zinc finger, RING-type[8], BIR repeat[9], CARD domain[10]
  • Molecular function: protein N-terminus binding[11], metal ion binding[12], cysteine-type endopeptidase inhibitor activity involved in apoptotic process[13], protein binding[14], transferase activity[15], ubiquitin binding[16], chaperone binding[17], FBXO family protein binding[18], zinc ion binding[19], transcription coactivator activity[20], ubiquitin-protein transferase activity[21], identical protein binding[22], ubiquitin protein ligase activity[23]
  • Cell component: cytosol[24], XY body[25], membrane raft[26], CD40 receptor complex[27], cytoplasmic side of plasma membrane[28], nucleus[29], cytoplasm[30], protein-containing complex[31]
  • Biological process: regulation of apoptotic process[32], regulation of nucleotide-binding oligomerization domain containing signaling pathway[33], positive regulation of protein K63-linked ubiquitination[34], response to hypoxia[35], regulation of transcription, DNA-templated[36], regulation of innate immune response[37], response to organic cyclic compound[38], negative regulation of ripoptosome assembly involved in necroptotic process[39], inhibition of cysteine-type endopeptidase activity involved in apoptotic process[40], placenta development[41], regulation of cysteine-type endopeptidase activity[42], regulation of RIG-I signaling pathway[43], regulation of tumor necrosis factor-mediated signaling pathway[44], tumor necrosis factor-mediated signaling pathway[45]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . wikidata.org.
  4. [6] ↑ . wikidata.org.
  5. [7] ↑ . wikidata.org.
  6. [8] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . Asymmetric recruitment of cIAPs by TRAF2. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . Interaction of heat-shock protein 90 beta isoform (HSP90 beta) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [21] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [22] ↑ . Systematic Analysis of Dimeric E3-RING Interactions Reveals Increased Combinatorial Complexity in Human Ubiquitination Networks. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [23] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [24] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [25] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [26] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [27] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  26. [28] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  27. [29] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  28. [30] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  29. [31] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  30. [32] ↑ . cIAPs block Ripoptosome formation, a RIP1/caspase-8 containing intracellular cell death complex differentially regulated by cFLIP isoforms. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  31. [33] ↑ . To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  32. [34] ↑ . cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4). Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  33. [35] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  34. [36] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  35. [37] ↑ . Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  36. [38] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  37. [39] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  38. [40] ↑ . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  39. [41] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  40. [42] ↑ . IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  41. [43] ↑ . To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  42. [44] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  43. [45] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Baculoviral IAP repeat containing 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/baculoviral-iap-repeat-containing-2-q21111704
MLA “Baculoviral IAP repeat containing 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/baculoviral-iap-repeat-containing-2-q21111704.
BibTeX @misc{4ortxyz_baculoviral-iap-repeat-containing-2-q21111704_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Baculoviral IAP repeat containing 2}}, year = {2026}, url = {https://4ort.xyz/entity/baculoviral-iap-repeat-containing-2-q21111704}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Baculoviral IAP repeat containing 2 — https://4ort.xyz/entity/baculoviral-iap-repeat-containing-2-q21111704 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → BIRC2
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → protein N-terminus binding, metal ion binding, cysteine-type endopeptidase inhibitor activity involved in apoptotic process +10
    + 13 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 2.3.2.27, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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