AXL receptor tyrosine kinase
mammalian protein found in Homo sapiens
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Summary
AXL receptor tyrosine kinase is a protein[1]. It is known by 5 alternative names across languages and contexts.[2]
Key Facts
- Physically interacts with: gilteritinib[3]
- Part of: Fibronectin type III superfamily[4], Immunoglobulin-like fold[5], Protein kinase-like domain superfamily[6], Immunoglobulin-like domain superfamily[7], membrane protein[8], Fibronectin type III, protein family[9], Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family[10], immunoglobulin subtype, protein family[11], Protein kinase domain, protein family[12], immunoglobulin-like domain, protein family[13], Protein kinase, ATP binding site, protein family[14], Tyrosine-protein kinase, catalytic domain, protein family[15], Tyrosine-protein kinase, active site, protein family[16]
- Has part(s): tyrosine-protein kinase, active site[17], fibronectin type III[18], protein kinase, ATP binding site[19], protein kinase domain[20], immunoglobulin-like domain[21], tyrosine-protein kinase, catalytic domain[22], serine-threonine/tyrosine-protein kinase, catalytic domain[23], immunoglobulin subtype[24]
- EC enzyme number: 2.7.10.1[25]
- Molecular function: nucleotide binding[26], protein kinase activity[27], transferase activity[28], virus receptor activity[29], kinase activity[30], protein heterodimerization activity[31], ATP binding[32], phosphatidylserine binding[33], protein binding[34], transmembrane receptor protein tyrosine kinase activity[35], phosphatidylinositol 3-kinase binding[36], myosin heavy chain binding[37], protein tyrosine kinase activity[38], Wnt-protein binding[39]
- Cell component: extracellular exosome[40], integral component of membrane[41], host cell surface[42], integral component of plasma membrane[43], cell surface[44], membrane[45], intracellular anatomical structure[46], plasma membrane[47], extracellular space[48], receptor complex[49]
- Biological process: protein kinase B signaling[50], positive regulation of natural killer cell differentiation[51], apoptotic cell clearance[52], negative regulation of lymphocyte activation[53], spermatogenesis[54], negative regulation of apoptotic process[55], signal transduction[56], natural killer cell differentiation[57], negative regulation of interferon-gamma production[58], cellular response to lipopolysaccharide[59], secretion by cell[60], vascular endothelial growth factor receptor signaling pathway[61], substrate adhesion-dependent cell spreading[62], erythrocyte homeostasis[63]