Argonaute RISC component 4

mammalian protein found in Homo sapiens

Protein protein Q21111277

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Summary

Argonaute RISC component 4 is a protein^[1].

Key Facts

Argonaute RISC component 4's instance of is recorded as protein^[2].
Argonaute RISC component 4's UniProt protein ID is recorded as Q9HCK5^[3].
Argonaute RISC component 4's part of is recorded as Ribonuclease H superfamily^[4].
Argonaute RISC component 4's part of is recorded as PAZ domain superfamily^[5].
Argonaute RISC component 4's part of is recorded as Protein argonaute-4^[6].
Argonaute RISC component 4's part of is recorded as Ribonuclease H-like superfamily^[7].
Argonaute RISC component 4's part of is recorded as Protein argonaute, N-terminal domain, protein family^[8].
Argonaute RISC component 4's part of is recorded as Piwi domain, protein family^[9].
Argonaute RISC component 4's part of is recorded as Argonaute linker 2 domain, protein family^[10].
Argonaute RISC component 4's part of is recorded as PAZ domain, protein family^[11].
Argonaute RISC component 4's part of is recorded as Protein argonaute, Mid domain, protein family^[12].
Argonaute RISC component 4's part of is recorded as Argonaute, linker 1 domain, protein family^[13].
Argonaute RISC component 4's has part is recorded as Argonaute linker 2 domain^[14].
Argonaute RISC component 4's has part is recorded as Protein argonaute, N-terminal^[15].
Argonaute RISC component 4's has part is recorded as PAZ domain^[16].
Argonaute RISC component 4's has part is recorded as Piwi domain^[17].
Argonaute RISC component 4's has part is recorded as Protein argonaute, Mid domain^[18].
Argonaute RISC component 4's has part is recorded as Argonaute, linker 1 domain^[19].
Argonaute RISC component 4's RefSeq protein ID is recorded as NP_060099^[20].
Argonaute RISC component 4's RefSeq protein ID is recorded as XP_005270635^[21].
Argonaute RISC component 4's RefSeq protein ID is recorded as XP_005270636^[22].
Argonaute RISC component 4's RefSeq protein ID is recorded as XP_011539185^[23].
Argonaute RISC component 4's RefSeq protein ID is recorded as XP_011539186^[24].
Argonaute RISC component 4's RefSeq protein ID is recorded as XP_024309563^[25].
Argonaute RISC component 4's molecular function is recorded as protein binding^[26].

⭐ Popularity Graph

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Quick Facts

Instance of protein

Part of Ribonuclease H superfamily, PAZ domain superfamily, Protein argonaute-4, Ribonuclease H-like superfamily, Protein argonaute, N-terminal domain, protein family, Piwi domain, protein family, Argonaute linker 2 domain, protein family, PAZ domain, protein family, Protein argonaute, Mid domain, protein family, Argonaute, linker 1 domain, protein family

Properties

Biological process mRNA destabilization-mediated gene silencing by siRNA, mRNA catabolic process, pre-miRNA processing, RNA interference, RNA secondary structure unwinding, mRNA destabilization-mediated gene silencing by miRNA, regulation of translation, production of miRNAs involved in gene silencing by miRNA, Wnt signaling pathway, calcium modulating pathway, gene silencing, regulation of cell morphogenesis, synaptonemal complex assembly, miRNA metabolic process, negative regulation of apoptotic process, male meiotic nuclear division, male gonad development, miRNA-mediated gene silencing by inhibition of translation, regulation of megakaryocyte differentiation, positive regulation of gene expression, negative regulation of gene expression, miRNA-mediated gene silencing by inhibition of translation

Cell component membrane, P-body, RISC-loading complex, cytoplasm, nucleus, nucleoplasm, cytosol, RISC complex, nuclear body, membrane, RISC complex

Encoded by AGO4

Found in taxon Homo sapiens

Has part(s) Argonaute linker 2 domain, Protein argonaute, N-terminal, PAZ domain, Piwi domain, Protein argonaute, Mid domain, Argonaute, linker 1 domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, single-stranded RNA binding, RNA binding, nucleic acid binding, double-stranded RNA binding, miRNA binding, miRNA binding

External References (3)

Ensembl protein id ENSP00000362306

Refseq protein id NP_060099, XP_005270635, XP_005270636, XP_011539185, XP_011539186, XP_024309563

Uniprot protein id Q9HCK5

🏷️ Also known as

en AGO4 en argonaute 4, RISC catalytic component en argonaute RISC catalytic component 4 en Argonaute RISC component 4 en eIF-2C 4 en eIF2C 4 en eukaryotic translation initiation factor 2C, 4 en Eukaryotic translation initiation factor 2C 4 en protein argonaute-4

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Argonaute RISC component 4 — instance of (P31): protein. UniProt. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Argonaute RISC component 4 — UniProt protein ID (P352): Q9HCK5. UniProt. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Argonaute RISC component 4 — part of (P361): Ribonuclease H superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Argonaute RISC component 4 — part of (P361): PAZ domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Argonaute RISC component 4 — part of (P361): Protein argonaute-4. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Argonaute RISC component 4 — part of (P361): Ribonuclease H-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Argonaute RISC component 4 — part of (P361): Protein argonaute, N-terminal domain, protein family. wikidata.org.
[9] ↑ Argonaute RISC component 4 — part of (P361): Piwi domain, protein family. wikidata.org.
[10] ↑ Argonaute RISC component 4 — part of (P361): Argonaute linker 2 domain, protein family. wikidata.org.
[11] ↑ Argonaute RISC component 4 — part of (P361): PAZ domain, protein family. wikidata.org.
[12] ↑ Argonaute RISC component 4 — part of (P361): Protein argonaute, Mid domain, protein family. wikidata.org.
[13] ↑ Argonaute RISC component 4 — part of (P361): Argonaute, linker 1 domain, protein family. wikidata.org.
[14] ↑ Argonaute RISC component 4 — has part(s) (P527): Argonaute linker 2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Argonaute RISC component 4 — has part(s) (P527): Protein argonaute, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Argonaute RISC component 4 — has part(s) (P527): PAZ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Argonaute RISC component 4 — has part(s) (P527): Piwi domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Argonaute RISC component 4 — has part(s) (P527): Protein argonaute, Mid domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Argonaute RISC component 4 — has part(s) (P527): Argonaute, linker 1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): NP_060099. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): XP_005270635. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): XP_005270636. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): XP_011539185. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): XP_011539186. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Argonaute RISC component 4 — RefSeq protein ID (P637): XP_024309563. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Argonaute RISC component 4 — molecular function (P680): protein binding. Involvement of microRNA in AU-rich element-mediated mRNA instability. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Argonaute RISC component 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Argonaute RISC component 4. Retrieved May 3, 2026, from https://4ort.xyz/entity/argonaute-risc-component-4-q21111277

MLA

“Argonaute RISC component 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/argonaute-risc-component-4-q21111277.

BibTeX

@misc{4ortxyz_argonaute-risc-component-4-q21111277_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Argonaute RISC component 4}}, year = {2026}, url = {https://4ort.xyz/entity/argonaute-risc-component-4-q21111277}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Argonaute RISC component 4 — https://4ort.xyz/entity/argonaute-risc-component-4-q21111277 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/argonaute-risc-component-4-q21111277 · Last refreshed: May 3, 2026