Argonaute RISC catalytic subunit 3

mammalian protein found in Mus musculus

Protein protein Q21498900

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Summary

Argonaute RISC catalytic subunit 3 is a protein^[1].

Key Facts

Argonaute RISC catalytic subunit 3's instance of is recorded as protein^[2].
Argonaute RISC catalytic subunit 3's subclass of is recorded as protein^[3].
Argonaute RISC catalytic subunit 3's UniProt protein ID is recorded as Q8CJF9^[4].
Argonaute RISC catalytic subunit 3's part of is recorded as Ribonuclease H superfamily^[5].
Argonaute RISC catalytic subunit 3's part of is recorded as Protein argonaute-3^[6].
Argonaute RISC catalytic subunit 3's part of is recorded as Ribonuclease H-like superfamily^[7].
Argonaute RISC catalytic subunit 3's part of is recorded as PAZ domain superfamily^[8].
Argonaute RISC catalytic subunit 3's part of is recorded as Protein argonaute, N-terminal domain, protein family^[9].
Argonaute RISC catalytic subunit 3's part of is recorded as Piwi domain, protein family^[10].
Argonaute RISC catalytic subunit 3's part of is recorded as Argonaute linker 2 domain, protein family^[11].
Argonaute RISC catalytic subunit 3's part of is recorded as PAZ domain, protein family^[12].
Argonaute RISC catalytic subunit 3's part of is recorded as Protein argonaute, Mid domain, protein family^[13].
Argonaute RISC catalytic subunit 3's part of is recorded as Argonaute, linker 1 domain, protein family^[14].
Argonaute RISC catalytic subunit 3's has part is recorded as Argonaute, linker 1 domain^[15].
Argonaute RISC catalytic subunit 3's has part is recorded as Piwi domain^[16].
Argonaute RISC catalytic subunit 3's has part is recorded as PAZ domain^[17].
Argonaute RISC catalytic subunit 3's has part is recorded as Argonaute linker 2 domain^[18].
Argonaute RISC catalytic subunit 3's has part is recorded as Protein argonaute, Mid domain^[19].
Argonaute RISC catalytic subunit 3's has part is recorded as Protein argonaute, N-terminal^[20].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as NP_700451^[21].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as XP_006502980^[22].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as XP_011238780^[23].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as XP_017175589^[24].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as XP_030109249^[25].
Argonaute RISC catalytic subunit 3's RefSeq protein ID is recorded as XP_030109250^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of Ribonuclease H superfamily, Protein argonaute-3, Ribonuclease H-like superfamily, PAZ domain superfamily, Protein argonaute, N-terminal domain, protein family, Piwi domain, protein family, Argonaute linker 2 domain, protein family, PAZ domain, protein family, Protein argonaute, Mid domain, protein family, Argonaute, linker 1 domain, protein family

Properties

Biological process miRNA-mediated gene silencing by inhibition of translation, regulation of stem cell proliferation, RNA secondary structure unwinding, pre-miRNA processing, production of miRNAs involved in gene silencing by miRNA, mRNA catabolic process, regulation of translation, gene silencing, positive regulation of gene expression, positive regulation of NIK/NF-kappaB signaling, mRNA destabilization-mediated gene silencing by miRNA, RNA phosphodiester bond hydrolysis, endonucleolytic, nucleic acid phosphodiester bond hydrolysis

Cell component condensed nuclear chromosome, RISC complex, RISC-loading complex, cytoplasm, nucleoplasm, P-body, cytoplasmic ribonucleoprotein granule

Encoded by Ago3

Found in taxon house mouse

Has part(s) Argonaute, linker 1 domain, Piwi domain, PAZ domain, Argonaute linker 2 domain, Protein argonaute, Mid domain, Protein argonaute, N-terminal

Imported from wholeness_audit_2026-05-02

Molecular function double-stranded RNA binding, nucleic acid binding, single-stranded RNA binding, miRNA binding, RNA binding, endoribonuclease activity, endoribonuclease activity, cleaving miRNA-paired mRNA, nuclease activity, endonuclease activity, endoribonuclease activity, hydrolase activity, metal ion binding, endoribonuclease activity, cleaving miRNA-paired mRNA

External References (3)

Ensembl protein id ENSMUSP00000066633, ENSMUSP00000116204, ENSMUSP00000118577

Refseq protein id NP_700451, XP_006502980, XP_011238780, XP_017175589, XP_030109249, XP_030109250, XP_030109251, XP_036019842, XP_036019844, XP_036019845

Uniprot protein id Q8CJF9

🏷️ Also known as

en Ago3 en argonaute 3 en argonaute3 en argonaute RISC catalytic component 3 en Argonaute RISC catalytic subunit 3 en eIF-2C 3 en eIF2C 3 en eukaryotic translation initiation factor 2C, 3 en Eukaryotic translation initiation factor 2C 3 en mAgo3 en Piwi/Argonaute family protein meIF2C3 en protein argonaute-3

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Argonaute RISC catalytic subunit 3 — instance of (P31): protein. UniProt. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Argonaute RISC catalytic subunit 3 — subclass of (P279): protein. UniProt. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Argonaute RISC catalytic subunit 3 — UniProt protein ID (P352): Q8CJF9. UniProt. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Ribonuclease H superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Protein argonaute-3. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Ribonuclease H-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): PAZ domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Protein argonaute, N-terminal domain, protein family. wikidata.org.
[10] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Piwi domain, protein family. wikidata.org.
[11] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Argonaute linker 2 domain, protein family. wikidata.org.
[12] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): PAZ domain, protein family. wikidata.org.
[13] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Protein argonaute, Mid domain, protein family. wikidata.org.
[14] ↑ Argonaute RISC catalytic subunit 3 — part of (P361): Argonaute, linker 1 domain, protein family. wikidata.org.
[15] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): Argonaute, linker 1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): Piwi domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): PAZ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): Argonaute linker 2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): Protein argonaute, Mid domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Argonaute RISC catalytic subunit 3 — has part(s) (P527): Protein argonaute, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): NP_700451. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): XP_006502980. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): XP_011238780. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): XP_017175589. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): XP_030109249. Q20641742. Retrieved 2022-03-20. wikidata.org.
[26] ↑ Argonaute RISC catalytic subunit 3 — RefSeq protein ID (P637): XP_030109250. Q20641742. Retrieved 2022-03-20. wikidata.org.

Class ancestry

[1] ↑ Argonaute RISC catalytic subunit 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Argonaute RISC catalytic subunit 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/argonaute-risc-catalytic-subunit-3

MLA

“Argonaute RISC catalytic subunit 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/argonaute-risc-catalytic-subunit-3.

BibTeX

@misc{4ortxyz_argonaute-risc-catalytic-subunit-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Argonaute RISC catalytic subunit 3}}, year = {2026}, url = {https://4ort.xyz/entity/argonaute-risc-catalytic-subunit-3}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Argonaute RISC catalytic subunit 3 — https://4ort.xyz/entity/argonaute-risc-catalytic-subunit-3 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/argonaute-risc-catalytic-subunit-3 · Last refreshed: May 3, 2026