Argonaute RISC catalytic component 3

mammalian protein found in Homo sapiens

Protein protein Q21111273

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Argonaute RISC catalytic component 3

Summary

Argonaute RISC catalytic component 3 is a protein^[1].

Key Facts

Argonaute RISC catalytic component 3's instance of is recorded as protein^[2].
Argonaute RISC catalytic component 3's UniProt protein ID is recorded as Q9H9G7^[3].
Argonaute RISC catalytic component 3's part of is recorded as Ribonuclease H superfamily^[4].
Argonaute RISC catalytic component 3's part of is recorded as Protein argonaute-3^[5].
Argonaute RISC catalytic component 3's part of is recorded as Ribonuclease H-like superfamily^[6].
Argonaute RISC catalytic component 3's part of is recorded as PAZ domain superfamily^[7].
Argonaute RISC catalytic component 3's part of is recorded as Protein argonaute, N-terminal domain, protein family^[8].
Argonaute RISC catalytic component 3's part of is recorded as Piwi domain, protein family^[9].
Argonaute RISC catalytic component 3's part of is recorded as Argonaute linker 2 domain, protein family^[10].
Argonaute RISC catalytic component 3's part of is recorded as PAZ domain, protein family^[11].
Argonaute RISC catalytic component 3's part of is recorded as Protein argonaute, Mid domain, protein family^[12].
Argonaute RISC catalytic component 3's part of is recorded as Argonaute, linker 1 domain, protein family^[13].
Argonaute RISC catalytic component 3's has part is recorded as Argonaute linker 2 domain^[14].
Argonaute RISC catalytic component 3's has part is recorded as Protein argonaute, N-terminal^[15].
Argonaute RISC catalytic component 3's has part is recorded as PAZ domain^[16].
Argonaute RISC catalytic component 3's has part is recorded as Piwi domain^[17].
Argonaute RISC catalytic component 3's has part is recorded as Protein argonaute, Mid domain^[18].
Argonaute RISC catalytic component 3's has part is recorded as Argonaute, linker 1 domain^[19].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as NP_079128^[20].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as NP_803171^[21].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as XP_005270632^[22].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as XP_005270633^[23].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as XP_011539181^[24].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as XP_011539184^[25].
Argonaute RISC catalytic component 3's RefSeq protein ID is recorded as XP_016856012^[26].

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Quick Facts

Instance of protein

Part of Ribonuclease H superfamily, Protein argonaute-3, Ribonuclease H-like superfamily, PAZ domain superfamily, Protein argonaute, N-terminal domain, protein family, Piwi domain, protein family, Argonaute linker 2 domain, protein family, PAZ domain, protein family, Protein argonaute, Mid domain, protein family, Argonaute, linker 1 domain, protein family

Properties

Biological process mRNA destabilization-mediated gene silencing by siRNA, mRNA catabolic process, pre-miRNA processing, RNA interference, RNA secondary structure unwinding, mRNA destabilization-mediated gene silencing by miRNA, regulation of stem cell proliferation, regulation of translation, production of miRNAs involved in gene silencing by miRNA, gene silencing, positive regulation of NIK/NF-kappaB signaling, positive regulation of gene expression, Wnt signaling pathway, calcium modulating pathway, miRNA-mediated gene silencing by inhibition of translation, regulation of megakaryocyte differentiation, positive regulation of gene expression, negative regulation of gene expression, miRNA-mediated gene silencing by inhibition of translation, mRNA destabilization-mediated gene silencing by miRNA, nucleic acid phosphodiester bond hydrolysis, RNA phosphodiester bond hydrolysis, endonucleolytic

Cell component cytoplasm, cytosol, membrane, RISC-loading complex, condensed nuclear chromosome, nucleoplasm, RISC complex, P-body, cytoplasmic ribonucleoprotein granule, membrane, RISC complex

Encoded by AGO3

Found in taxon Homo sapiens

Has part(s) Argonaute linker 2 domain, Protein argonaute, N-terminal, PAZ domain, Piwi domain, Protein argonaute, Mid domain, Argonaute, linker 1 domain

Imported from wholeness_audit_2026-05-02

Molecular function protein binding, single-stranded RNA binding, nucleic acid binding, double-stranded RNA binding, miRNA binding, RNA binding, RNA binding, nuclease activity, endonuclease activity, endoribonuclease activity, hydrolase activity, miRNA binding, metal ion binding, endoribonuclease activity, cleaving miRNA-paired mRNA

External References (3)

Ensembl protein id ENSP00000246314, ENSP00000362287, ENSP00000317425, ENSP00000380928, ENSP00000489286

Refseq protein id NP_079128, NP_803171, XP_005270632, XP_005270633, XP_011539181, XP_011539184, XP_016856012, XP_016856013, XP_016856014, XP_016856015, XP_016856016, XP_016856017

Uniprot protein id Q9H9G7

🏷️ Also known as

en AGO3 en argonaute 3, RISC catalytic component en Argonaute RISC catalytic component 3 en eIF-2C 3 en eIF2C 3 en eukaryotic translation initiation factor 2C, 3 en Eukaryotic translation initiation factor 2C 3 en hAgo3 en protein argonaute-3

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Argonaute RISC catalytic component 3 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Argonaute RISC catalytic component 3 — UniProt protein ID (P352): Q9H9G7. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Argonaute RISC catalytic component 3 — part of (P361): Ribonuclease H superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Argonaute RISC catalytic component 3 — part of (P361): Protein argonaute-3. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Argonaute RISC catalytic component 3 — part of (P361): Ribonuclease H-like superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Argonaute RISC catalytic component 3 — part of (P361): PAZ domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Argonaute RISC catalytic component 3 — part of (P361): Protein argonaute, N-terminal domain, protein family. wikidata.org.
[9] ↑ Argonaute RISC catalytic component 3 — part of (P361): Piwi domain, protein family. wikidata.org.
[10] ↑ Argonaute RISC catalytic component 3 — part of (P361): Argonaute linker 2 domain, protein family. wikidata.org.
[11] ↑ Argonaute RISC catalytic component 3 — part of (P361): PAZ domain, protein family. wikidata.org.
[12] ↑ Argonaute RISC catalytic component 3 — part of (P361): Protein argonaute, Mid domain, protein family. wikidata.org.
[13] ↑ Argonaute RISC catalytic component 3 — part of (P361): Argonaute, linker 1 domain, protein family. wikidata.org.
[14] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): Argonaute linker 2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): Protein argonaute, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): PAZ domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): Piwi domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): Protein argonaute, Mid domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Argonaute RISC catalytic component 3 — has part(s) (P527): Argonaute, linker 1 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): NP_079128. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): NP_803171. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): XP_005270632. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): XP_005270633. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): XP_011539181. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): XP_011539184. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Argonaute RISC catalytic component 3 — RefSeq protein ID (P637): XP_016856012. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Argonaute RISC catalytic component 3 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Argonaute RISC catalytic component 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/argonaute-risc-catalytic-component-3

MLA

“Argonaute RISC catalytic component 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/argonaute-risc-catalytic-component-3.

BibTeX

@misc{4ortxyz_argonaute-risc-catalytic-component-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Argonaute RISC catalytic component 3}}, year = {2026}, url = {https://4ort.xyz/entity/argonaute-risc-catalytic-component-3}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Argonaute RISC catalytic component 3 — https://4ort.xyz/entity/argonaute-risc-catalytic-component-3 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/argonaute-risc-catalytic-component-3 · Last refreshed: May 3, 2026