Annexin A6

mammalian protein found in Homo sapiens

Protein protein Q21154929

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Annexin A6

Summary

Annexin A6 is a protein^[1].

Key Facts

Annexin A6's instance of is recorded as protein^[2].
Annexin A6's UniProt protein ID is recorded as P08133^[3].
Annexin A6's part of is recorded as Annexin A6^[4].
Annexin A6's part of is recorded as Annexin superfamily^[5].
Annexin A6's part of is recorded as Annexin^[6].
Annexin A6's part of is recorded as Annexin repeat, conserved site, protein family^[7].
Annexin A6's part of is recorded as Annexin repeat, protein family^[8].
Annexin A6's has part is recorded as Annexin repeat^[9].
Annexin A6's has part is recorded as Annexin repeat, conserved site^[10].
Annexin A6's RefSeq protein ID is recorded as NP_001146^[11].
Annexin A6's RefSeq protein ID is recorded as NP_001180473^[12].
Annexin A6's RefSeq protein ID is recorded as NP_001350043^[13].
Annexin A6's PDB structure ID is recorded as 1M9I^[14].
Annexin A6's molecular function is recorded as calcium ion binding^[15].
Annexin A6's molecular function is recorded as protein homodimerization activity^[16].
Annexin A6's molecular function is recorded as GTP binding^[17].
Annexin A6's molecular function is recorded as calcium-dependent protein binding^[18].
Annexin A6's molecular function is recorded as cholesterol binding^[19].
Annexin A6's molecular function is recorded as protein binding^[20].
Annexin A6's molecular function is recorded as ligand-gated ion channel activity^[21].
Annexin A6's molecular function is recorded as calcium-dependent phospholipid binding^[22].
Annexin A6's molecular function is recorded as lipid binding^[23].
Annexin A6's molecular function is recorded as phosphatidylserine binding^[24].
Annexin A6's molecular function is recorded as calcium channel activity^[25].
Annexin A6's molecular function is recorded as GTP binding^[26].

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Quick Facts

Instance of protein

Part of Annexin A6, Annexin superfamily, Annexin, Annexin repeat, conserved site, protein family, Annexin repeat, protein family

Properties

Biological process regulation of muscle contraction, mitochondrial calcium ion homeostasis, ion transmembrane transport, apoptotic signaling pathway, protein homooligomerization, calcium ion transport, neural crest cell migration, plasma membrane repair, growth plate cartilage chondrocyte differentiation, regulation of muscle contraction, biomineral tissue development, protein homooligomerization, negative regulation of sequestering of calcium ion, mitochondrial calcium ion homeostasis, calcium ion import, calcium ion transmembrane transport, apoptotic signaling pathway

Cell component cytoplasm, membrane, late endosome membrane, focal adhesion, melanosome, lysosomal membrane, mitochondrion, perinuclear region of cytoplasm, extracellular exosome, focal adhesion, membrane, collagen-containing extracellular matrix, extracellular exosome

Encoded by ANXA6

Found in taxon Homo sapiens

Has part(s) Annexin repeat, Annexin repeat, conserved site

Imported from wholeness_audit_2026-05-02

Molecular function calcium ion binding, protein homodimerization activity, GTP binding, calcium-dependent protein binding, cholesterol binding, protein binding, ligand-gated ion channel activity, calcium-dependent phospholipid binding, lipid binding, phosphatidylserine binding, calcium channel activity, GTP binding, calcium-dependent phospholipid binding, heparin binding, ligand-gated ion channel activity, cholesterol binding, enzyme binding, chondroitin sulfate binding, signaling receptor activity, protein homodimerization activity, protein-containing complex binding, calcium-dependent protein binding, actin filament binding

External References (5)

Ensembl protein id ENSP00000346550, ENSP00000430517, ENSP00000366980, ENSP00000428916, ENSP00000430420, ENSP00000430429, ENSP00000430572, ENSP00000430663, ENSP00000430826, ENSP00000431078, ENSP00000431086

Pdb structure id 1M9I

Refseq protein id NP_001146, NP_001180473, NP_001350043

Transporter classification database id 1.A.31.1.2

Uniprot protein id P08133

🏷️ Also known as

en 67 kDa calelectrin en annexin-6 en Annexin A6 en Annexin VI en annexin VI (p68) en ANXA6 en calcium-binding protein p68 en calelectrin en calphobindin II en Calphobindin-II en chromobindin-20 en CPB-II en lipocortin VI en p68 en p70 en Protein III en testis secretory sperm-binding protein Li 198a

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Annexin A6 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Annexin A6 — UniProt protein ID (P352): P08133. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Annexin A6 — part of (P361): Annexin A6. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Annexin A6 — part of (P361): Annexin superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Annexin A6 — part of (P361): Annexin. Retrieved 2019-10-02. wikidata.org.
[7] ↑ Annexin A6 — part of (P361): Annexin repeat, conserved site, protein family. wikidata.org.
[8] ↑ Annexin A6 — part of (P361): Annexin repeat, protein family. wikidata.org.
[9] ↑ Annexin A6 — has part(s) (P527): Annexin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Annexin A6 — has part(s) (P527): Annexin repeat, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Annexin A6 — RefSeq protein ID (P637): NP_001146. Q20641742. Retrieved 2020-05-30. wikidata.org.
[12] ↑ Annexin A6 — RefSeq protein ID (P637): NP_001180473. Q20641742. Retrieved 2020-05-30. wikidata.org.
[13] ↑ Annexin A6 — RefSeq protein ID (P637): NP_001350043. Q20641742. Retrieved 2020-05-30. wikidata.org.
[14] ↑ Annexin A6 — PDB structure ID (P638): 1M9I. Q905695. Retrieved 2016-08-09. wikidata.org.
[15] ↑ Annexin A6 — molecular function (P680): calcium ion binding. GOA. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[16] ↑ Annexin A6 — molecular function (P680): protein homodimerization activity. Effects of mutagenesis of W343 in human annexin A6 isoform 1 on its interaction with GTP: nucleotide-induced oligomer formation and ion channel activity. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Annexin A6 — molecular function (P680): GTP binding. Effects of mutagenesis of W343 in human annexin A6 isoform 1 on its interaction with GTP: nucleotide-induced oligomer formation and ion channel activity. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Annexin A6 — molecular function (P680): calcium-dependent protein binding. Identification and characterization of the acidic pH binding sites for growth regulatory ligands of low density lipoprotein receptor-related protein-1. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Annexin A6 — molecular function (P680): cholesterol binding. Interaction of AnxA6 with isolated and artificial lipid microdomains; importance of lipid composition and calcium content. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Annexin A6 — molecular function (P680): protein binding. Tumor protein D52 (TPD52): a novel B-cell/plasma-cell molecule with unique expression pattern and Ca(2+)-dependent association with annexin VI. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Annexin A6 — molecular function (P680): ligand-gated ion channel activity. Effects of mutagenesis of W343 in human annexin A6 isoform 1 on its interaction with GTP: nucleotide-induced oligomer formation and ion channel activity. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Annexin A6 — molecular function (P680): calcium-dependent phospholipid binding. GOA. Retrieved 2017-09-26. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Annexin A6 — molecular function (P680): lipid binding. Effects of mutagenesis of W343 in human annexin A6 isoform 1 on its interaction with GTP: nucleotide-induced oligomer formation and ion channel activity. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Annexin A6 — molecular function (P680): phosphatidylserine binding. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Annexin A6 — molecular function (P680): calcium channel activity. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Annexin A6 — molecular function (P680): GTP binding. Effects of mutagenesis of W343 in human annexin A6 isoform 1 on its interaction with GTP: nucleotide-induced oligomer formation and ion channel activity. Retrieved 2019-04-08. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Annexin A6 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Annexin A6. Retrieved May 3, 2026, from https://4ort.xyz/entity/annexin-a6

MLA “Annexin A6.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/annexin-a6.

BibTeX

@misc{4ortxyz_annexin-a6_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Annexin A6}}, year = {2026}, url = {https://4ort.xyz/entity/annexin-a6}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Annexin A6 — https://4ort.xyz/entity/annexin-a6 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/annexin-a6 · Last refreshed: May 3, 2026