Ankyrin 2

mammalian protein found in Homo sapiens

Protein protein Q21097261

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Ankyrin 2

Summary

Ankyrin 2 is a protein^[1].

Key Facts

Ankyrin 2's instance of is recorded as protein^[2].
Ankyrin 2's UniProt protein ID is recorded as Q01484^[3].
Ankyrin 2's part of is recorded as Death-like domain superfamily^[4].
Ankyrin 2's part of is recorded as Ankyrin repeat-containing domain superfamily^[5].
Ankyrin 2's part of is recorded as auxiliary protein involved in transmembrane transport^[6].
Ankyrin 2's part of is recorded as Ankyrin repeat-containing domain, protein family^[7].
Ankyrin 2's part of is recorded as Death domain, protein family^[8].
Ankyrin 2's part of is recorded as ZU5 domain, protein family^[9].
Ankyrin 2's part of is recorded as Ankyrin repeat, protein family^[10].
Ankyrin 2's has part is recorded as ZU5 domain^[11].
Ankyrin 2's has part is recorded as death domain^[12].
Ankyrin 2's has part is recorded as ankyrin repeat-containing domain^[13].
Ankyrin 2's has part is recorded as ankyrin repeat^[14].
Ankyrin 2's RefSeq protein ID is recorded as NP_001120965^[15].
Ankyrin 2's RefSeq protein ID is recorded as NP_001139^[16].
Ankyrin 2's RefSeq protein ID is recorded as NP_066187^[17].
Ankyrin 2's RefSeq protein ID is recorded as XP_005263002^[18].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863556^[19].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863558^[20].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863560^[21].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863561^[22].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863562^[23].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863563^[24].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863564^[25].
Ankyrin 2's RefSeq protein ID is recorded as XP_016863565^[26].

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Quick Facts

Instance of protein

Part of Death-like domain superfamily, Ankyrin repeat-containing domain superfamily, auxiliary protein involved in transmembrane transport, Ankyrin repeat-containing domain, protein family, Death domain, protein family, ZU5 domain, protein family, Ankyrin repeat, protein family

Properties

Biological process positive regulation of potassium ion transmembrane transporter activity, protein localization to organelle, positive regulation of cation channel activity, regulation of cardiac muscle contraction by calcium ion signaling, regulation of calcium ion transport, regulation of protein stability, regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion, positive regulation of potassium ion transport, regulation of release of sequestered calcium ion into cytosol, SA node cell action potential, protein stabilization, ventricular cardiac muscle cell action potential, cellular calcium ion homeostasis, positive regulation of calcium ion transmembrane transporter activity, nervous system development, regulation of heart rate, protein localization to M-band, endoplasmic reticulum to Golgi vesicle-mediated transport, regulation of cardiac muscle cell contraction, protein localization to T-tubule, positive regulation of gene expression, protein localization to cell surface, paranodal junction assembly, atrial cardiac muscle cell action potential, sarcoplasmic reticulum calcium ion transport, SA node cell to atrial cardiac muscle cell communication, membrane depolarization during SA node cell action potential, atrial cardiac muscle cell to AV node cell communication, regulation of cardiac muscle contraction, protein localization to endoplasmic reticulum, response to methylmercury, regulation of SA node cell action potential, regulation of heart rate by cardiac conduction, atrial septum development, regulation of calcium ion transmembrane transporter activity, signal transduction, regulation of atrial cardiac muscle cell action potential, T-tubule organization, positive regulation of calcium ion transport, regulation of ventricular cardiac muscle cell membrane repolarization, cytoskeleton organization, protein localization to plasma membrane, endocytosis, protein transport, protein localization to plasma membrane

Cell component M band, cytoplasm, cytosol, postsynaptic membrane, membrane, intercalated disc, T-tubule, synapse, intracellular anatomical structure, cell junction, basolateral plasma membrane, Z discdkac, apical plasma membrane, membrane raft, neuron projection, sarcolemma, A band, cytoskeleton, costamere, mitochondrion, lysosome, endosome, early endosome, recycling endosome, plasma membrane, plasma membrane, membrane, costamere, axon initial segment, Z discdkac, T-tubule

Encoded by ANK2

Exact match purl.uniprot.org

Found in taxon Homo sapiens

Has part(s) ZU5 domain, death domain, ankyrin repeat-containing domain, ankyrin repeat

Imported from wholeness_audit_2026-05-02

Molecular function protein-macromolecule adaptor activity, spectrin binding, transmembrane transporter binding, ATPase binding, structural constituent of cytoskeleton, protein binding, enzyme binding, protein kinase binding, transmembrane transporter binding, phosphorylation-dependent protein binding

External References (5)

Ensembl protein id ENSP00000500947, ENSP00000421011, ENSP00000500459, ENSP00000500712, ENSP00000499943, ENSP00000500473, ENSP00000425775, ENSP00000500918, ENSP00000424722, ENSP00000499891, ENSP00000500245, ENSP00000500102, ENSP00000499996, ENSP00000500954, ENSP00000489091, ENSP00000500548, ENSP00000421023, ENSP00000482888, ENSP00000500780, ENSP00000499887, ENSP00000499837, ENSP00000499967, ENSP00000500937, ENSP00000499928, ENSP00000500539, ENSP00000378044, ENSP00000426944, ENSP00000500544, ENSP00000500842, ENSP00000499870, ENSP00000500843, ENSP00000500933, ENSP00000500528, ENSP00000500540, ENSP00000499990, ENSP00000500833, ENSP00000423799, ENSP00000500866, ENSP00000500222, ENSP00000499986, ENSP00000500378, ENSP00000500423, ENSP00000500524, ENSP00000500111, ENSP00000422498, ENSP00000500112, ENSP00000499979, ENSP00000499913, ENSP00000500580, ENSP00000426994, ENSP00000499828, ENSP00000500269, ENSP00000500622, ENSP00000500522, ENSP00000500881, ENSP00000499832, ENSP00000500420, ENSP00000422888, ENSP00000349588, ENSP00000499959, ENSP00000499902, ENSP00000264366, ENSP00000499869, ENSP00000499953, ENSP00000500150, ENSP00000500832, ENSP00000500883, ENSP00000500872, ENSP00000500908, ENSP00000500311, ENSP00000500854, ENSP00000421067, ENSP00000500926, ENSP00000500265, ENSP00000500855, ENSP00000499881, ENSP00000500645, ENSP00000422853, ENSP00000499982, ENSP00000500275, ENSP00000422486, ENSP00000500007, ENSP00000500527, ENSP00000501302, ENSP00000501090

Pdb structure id 4D8O, 4RLV, 4RLY

Refseq protein id NP_001120965, NP_001139, NP_066187, XP_005263002, XP_016863556, XP_016863558, XP_016863560, XP_016863561, XP_016863562, XP_016863563, XP_016863564, XP_016863565, XP_016863566, XP_016863567, XP_016863569, NP_001341154, NP_001341157, NP_001341159, NP_001341160, NP_001341161, NP_001341164, NP_001341165, NP_001341166, NP_001341168, NP_001341169, NP_001341170, NP_001341171, NP_001341172, NP_001341173, NP_001341174, NP_001341175, NP_001341178, NP_001341181, NP_001341182, NP_001341183, NP_001341184, NP_001341185, NP_001341186, NP_001341187, NP_001341189, NP_001341190, NP_001341191, NP_001341193, NP_001341194, NP_001341195, NP_001341196, NP_001341197, NP_001341198, NP_001341199, NP_001341200, NP_001341201, NP_001341202, NP_001341203, NP_001341204, NP_001341205, NP_001341206, NP_001341207, NP_001341208, NP_001341209, NP_001341210, NP_001341211, XP_024309784, XP_024309785, XP_024309786, XP_024309787, XP_024309788, XP_024309789, XP_024309790, XP_024309791

Transporter classification database id 8.A.28.1.1

Uniprot protein id Q01484

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Ankyrin 2 — instance of (P31): protein. Q905695. Retrieved 2019-11-13. wikidata.org.
[3] ↑ Ankyrin 2 — UniProt protein ID (P352): Q01484. Q905695. Retrieved 2019-11-13. wikidata.org.
[4] ↑ Ankyrin 2 — part of (P361): Death-like domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Ankyrin 2 — part of (P361): Ankyrin repeat-containing domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Ankyrin 2 — part of (P361): auxiliary protein involved in transmembrane transport. Retrieved 2019-10-02. wikidata.org.
[7] ↑ Ankyrin 2 — part of (P361): Ankyrin repeat-containing domain, protein family. wikidata.org.
[8] ↑ Ankyrin 2 — part of (P361): Death domain, protein family. wikidata.org.
[9] ↑ Ankyrin 2 — part of (P361): ZU5 domain, protein family. wikidata.org.
[10] ↑ Ankyrin 2 — part of (P361): Ankyrin repeat, protein family. wikidata.org.
[11] ↑ Ankyrin 2 — has part(s) (P527): ZU5 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Ankyrin 2 — has part(s) (P527): death domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Ankyrin 2 — has part(s) (P527): ankyrin repeat-containing domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Ankyrin 2 — has part(s) (P527): ankyrin repeat. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Ankyrin 2 — RefSeq protein ID (P637): NP_001120965. Q20641742. Retrieved 2020-05-30. wikidata.org.
[16] ↑ Ankyrin 2 — RefSeq protein ID (P637): NP_001139. Q20641742. Retrieved 2020-05-30. wikidata.org.
[17] ↑ Ankyrin 2 — RefSeq protein ID (P637): NP_066187. Q20641742. Retrieved 2020-05-30. wikidata.org.
[18] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_005263002. Q20641742. Retrieved 2020-05-30. wikidata.org.
[19] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863556. Q20641742. Retrieved 2020-05-30. wikidata.org.
[20] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863558. Q20641742. Retrieved 2020-05-30. wikidata.org.
[21] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863560. Q20641742. Retrieved 2020-05-30. wikidata.org.
[22] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863561. Q20641742. Retrieved 2020-05-30. wikidata.org.
[23] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863562. Q20641742. Retrieved 2020-05-30. wikidata.org.
[24] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863563. Q20641742. Retrieved 2020-05-30. wikidata.org.
[25] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863564. Q20641742. Retrieved 2020-05-30. wikidata.org.
[26] ↑ Ankyrin 2 — RefSeq protein ID (P637): XP_016863565. Q20641742. Retrieved 2020-05-30. wikidata.org.

Class ancestry

[1] ↑ Ankyrin 2 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Ankyrin 2. Retrieved May 3, 2026, from https://4ort.xyz/entity/ankyrin-2

MLA “Ankyrin 2.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/ankyrin-2.

BibTeX

@misc{4ortxyz_ankyrin-2_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Ankyrin 2}}, year = {2026}, url = {https://4ort.xyz/entity/ankyrin-2}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Ankyrin 2 — https://4ort.xyz/entity/ankyrin-2 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/ankyrin-2 · Last refreshed: May 3, 2026