Properties
Biological process
negative regulation of cell population proliferation, positive regulation of cell differentiation, positive regulation of NF-kappaB transcription factor activity, sex differentiation, signal transduction, negative regulation of integrin biosynthetic process, cell-cell signaling, intracellular receptor signaling pathway, prostate gland development, positive regulation of integrin biosynthetic process, positive regulation of phosphorylation, androgen receptor signaling pathway, positive regulation of gene expression, positive regulation of cell population proliferation, positive regulation of transcription, DNA-templated, negative regulation of extrinsic apoptotic signaling pathway, transcription initiation from RNA polymerase II promoter, regulation of transcription, DNA-templated, cell population proliferation, cell growth, positive regulation of transcription by RNA polymerase III, protein complex oligomerization, transcription, DNA-templated, positive regulation of insulin-like growth factor receptor signaling pathway, male somatic sex determination, positive regulation of intracellular estrogen receptor signaling pathway, negative regulation of epithelial cell proliferation, regulation of gene expression, regulation of systemic arterial blood pressure, positive regulation of transcription by RNA polymerase II, animal organ formation, multicellular organism growth, positive regulation of MAPK cascade, in utero embryonic development, reproductive system development, tertiary branching involved in mammary gland duct morphogenesis, cellular process or phenomenon, male gonad development, single fertilization, fertilization, regulation of prostatic bud formation, mammary gland alveolus development, epithelial cell differentiation involved in prostate gland development, epithelial cell morphogenesis, regulation of transcription by RNA polymerase II, seminiferous tubule development, morphogenesis of an epithelial fold, prostate gland epithelium morphogenesis, Leydig cell differentiation, reproductive structure development, regulation of catalytic activity, regulation of developmental growth, lateral sprouting involved in mammary gland duct morphogenesis, male genitalia morphogenesis, prostate gland growth, activation of prostate induction by androgen receptor signaling pathway, spermatogenesis, protein deubiquitination, positive regulation of epithelial cell proliferation involved in prostate gland development, negative regulation of transcription by RNA polymerase II, cellular response to steroid hormone stimulus, cellular response to testosterone stimulus, regulation of protein localization to plasma membrane, transcription, DNA-templated, positive regulation of gene expression
Has part(s)
nuclear hormone receptor-type zinc finger, Nuclear hormone receptor, ligand-binding domain
Has parts
nuclear hormone receptor-type zinc finger, Nuclear hormone receptor, ligand-binding domain
Molecular function
metal ion binding, lipid binding, signaling receptor binding, sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, protein dimerization activity, chromatin binding, zinc ion binding, nuclear receptor activity, ATPase binding, androgen binding, steroid binding, DNA-binding transcription activator activity, RNA polymerase II-specific, transcription factor binding, protein binding, DNA binding, beta-catenin binding, POU domain binding, enzyme binding, DNA-binding transcription factor activity, DNA-binding transcription factor activity, RNA polymerase II-specific, RNA polymerase II general transcription initiation factor binding, DNA-binding transcription factor activity, steroid hormone receptor activity, nuclear receptor activity, DNA binding
Part of
Nuclear hormone receptor-like domain superfamily, Androgen receptor, Zinc finger, NHR/GATA-type, Nuclear hormone receptor, ligand-binding domain, protein family, Zinc finger, nuclear hormone receptor-type, protein family
Physically interacts with
andarine, dihydrotestosterone, dromostanolone propionate, ethylestrenol, fluoxymesterone, metribolone, mibolerone, nandrolone, testosterone propionate, methyltestosterone, bicalutamide, bisphenol A, cyproterone acetate, enzalutamide, flutamide, hydroxyflutamide, mifepristone, nilutamide
External References (10)
Ensembl protein id
ENSP00000379358, ENSP00000421155, ENSP00000363822, ENSP00000484033, ENSP00000379359, ENSP00000425199, ENSP00000482407, ENSP00000479013
Freebase id
/m/06yz20
Mesh descriptor id
D011944
Mesh tree code
D12.776.826.750.150
Microsoft academic id (discontinued)
61367390, 2910063059
Openalex id
C61367390
Pdb structure id
1E3G, 1GS4, 1T5Z, 1T63, 1T65, 1XJ7, 1XOW, 1XQ3, 1Z95, 2AM9, 2AMA, 2AMB, 2AO6, 2AX6, 2AX7, 2AX8, 2AX9, 2AXA, 2HVC, 2OZ7, 2PIO, 2PIP, 2PIQ, 2PIR, 2PIT, 2PIU, 2PIV, 2PIW, 2PIX, 2PKL, 2PNU, 2Q7I, 2Q7J, 2Q7K, 2YHD, 2YLO, 2YLP, 2YLQ, 2Z4J, 3B5R, 3B65, 3B66, 3B67, 3B68, 3BTR, 3V49, 3V4A, 3ZQT, 4HLW, 3L3X, 3L3Z, 3RLJ, 3RLL, 4K7A, 4OEA, 4OED, 4OEY, 4OEZ, 4OFR, 4OFU, 4OGH, 4OH5, 4OH6, 4OHA, 4OIL, 4OIU, 4OJ9, 4OJB, 4OK1, 4OKB, 4OKT, 4OKW, 4OKX, 4OLM, 4QL8, 5CJ6
Refseq protein id
NP_000035, NP_001011645, NP_001334990, NP_001334992, NP_001334993
Umls cui
C0034786
Uniprot protein id
P10275