Addison's disease

adrenal cortical hypofunction that is characterized by insufficient steroid hormone production by the adrenal glands
MedicalCondition designated_intractable_rare_disease Q8282
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Summary

Addison's disease is a designated intractable/rare disease[1]. It ranks in the top 8% of designated intractable rare disease entities by monthly Wikipedia readership (15,011 views/month).[2]

Key Facts

  • Instance of: class of disease[3]
  • Named after: Thomas Addison[4]
  • Subclass of: adrenal cortical hypofunction[5], endocrine system disease[6], female reproductive system disease[7], kidney disease[8], male reproductive system disease[9], disease[10]
  • Commons category: Addison's disease[11]
  • Symptoms and signs: fatigue[12], anorexia[13], muscle weakness[14], weight loss[15], abdominal pain[16]
  • External data available at URL: http://www.nanbyou.or.jp/entry/44[17]
  • Described by source: Small Brockhaus and Efron Encyclopedic Dictionary[18], Brockhaus and Efron Encyclopedic Dictionary[19], Encyclopædia Britannica 11th edition[20], Otto's encyclopedia[21], Great Soviet Encyclopedia (1926–1947)[22], Granat Encyclopedic Dictionary[23], Armenian Soviet Encyclopedia, vol. 1[24]
  • ICD-9-CM: 255.41[25]
  • NCI Thesaurus ID: C26689[26]
  • Health specialty: endocrinology[27]
  • Drug or therapy used for treatment: dexamethasone[28], fludrocortisone[29]
  • Exact match: http://purl.obolibrary.org/obo/DOID_13774[30], http://identifiers.org/doid/DOID:13774[31], http://purl.obolibrary.org/obo/HP_0008207[32], http://www.orpha.net/ORDO/Orphanet_85138[33]
  • On focus list of Wikimedia project: WikiProject Medicine[34]

Why It Matters

Addison's disease has Wikipedia articles in 29 language editions, a strong signal of global cultural recognition.[35] It is known by 57 alternative names across languages and contexts.[36]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . wikidata.org.
  3. [5] ↑ . Disease Ontology. Retrieved . wikidata.org.
  4. [6] ↑ . Genetic and Rare Diseases Information Center. Retrieved . wikidata.org.
  5. [7] ↑ . Genetic and Rare Diseases Information Center. Retrieved . wikidata.org.
  6. [8] ↑ . Genetic and Rare Diseases Information Center. Retrieved . wikidata.org.
  7. [9] ↑ . Genetic and Rare Diseases Information Center. Retrieved . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . web.archive.org. web.archive.org. Provenance: wikidata.org.
  11. [13] ↑ . web.archive.org. web.archive.org. Provenance: wikidata.org.
  12. [14] ↑ . web.archive.org. web.archive.org. Provenance: wikidata.org.
  13. [15] ↑ . web.archive.org. web.archive.org. Provenance: wikidata.org.
  14. [16] ↑ . web.archive.org. web.archive.org. Provenance: wikidata.org.
  15. [17] ↑ . ddrare.nibiohn.go.jp. Retrieved . ddrare.nibiohn.go.jp. Provenance: wikidata.org.
  16. [18] ↑ . wikidata.org.
  17. [19] ↑ . wikidata.org.
  18. [20] ↑ . wikidata.org.
  19. [21] ↑ . wikidata.org.
  20. [22] ↑ . wikidata.org.
  21. [23] ↑ . wikidata.org.
  22. [24] ↑ . wikidata.org.
  23. [25] ↑ . wikidata.org.
  24. [26] ↑ . Disease Ontology. Retrieved . wikidata.org.
  25. [27] ↑ . wikidata.org.
  26. [28] ↑ . NDF-RT. Retrieved . wikidata.org.
  27. [29] ↑ . NDF-RT. Retrieved . wikidata.org.
  28. [30] ↑ . Disease Ontology. Retrieved . wikidata.org.
  29. [31] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  30. [32] ↑ . Human Phenotype Ontology release 2018-03-08. Retrieved . wikidata.org.
  31. [33] ↑ . wikidata.org.
  32. [34] ↑ . wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [35] ↑ . Wikidata sitelinks. wikidata.org.
  3. [36] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Addison's disease. Retrieved October 14, 2026, from https://4ort.xyz/entity/addison-s-disease
MLA “Addison's disease.” 4ort.xyz Knowledge Graph, 4ort.xyz, 14 Oct. 2026, https://4ort.xyz/entity/addison-s-disease.
BibTeX @misc{4ortxyz_addison-s-disease_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Addison's disease}}, year = {2026}, url = {https://4ort.xyz/entity/addison-s-disease}, note = {Accessed: 2026-10-14}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Addison's disease — https://4ort.xyz/entity/addison-s-disease (retrieved 2026-10-14)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 15w ago · JhealdBatch bot · 2026-07-03 view diff on Wikidata ↗
    Subclass of → adrenal cortical hypofunction, endocrine system disease, female reproductive system disease +3
    "/* wbeditentity-update:0| */ QuickStatements 3.0 [[:toollabs:qs-dev/batch/39732|batch #39732]]: rm redundant subclass"
  2. 21w ago · Twofivesixbot bot · 2026-05-20 view diff on Wikidata ↗
    On focus list of wikimedia project → WikiProject Medicine
    Named after → Thomas Addison
    Instance of → —
    Subclass of → adrenal cortical hypofunction, endocrine system disease, female reproductive system disease +3
    + 8 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|7 */ Yso id: 17277, mv to monolingual text names on YSO statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.