activating transcription factor 6

mammalian protein found in Homo sapiens
Protein protein Q21116808
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activating transcription factor 6

Summary

activating transcription factor 6 is a protein[1].

Key Facts

  • activating transcription factor 6's instance of is recorded as protein[2].
  • activating transcription factor 6's UniProt protein ID is recorded as P18850[3].
  • activating transcription factor 6's part of is recorded as cAMP-dependent transcription factor ATF-6 alpha[4].
  • activating transcription factor 6's part of is recorded as Basic-leucine zipper domain, protein family[5].
  • activating transcription factor 6's MeSH descriptor ID is recorded as C497111[6].
  • activating transcription factor 6's has part is recorded as Basic-leucine zipper domain[7].
  • activating transcription factor 6's RefSeq protein ID is recorded as NP_031374[8].
  • activating transcription factor 6's RefSeq protein ID is recorded as XP_006711287[9].
  • activating transcription factor 6's RefSeq protein ID is recorded as XP_011507610[10].
  • activating transcription factor 6's RefSeq protein ID is recorded as XP_011507611[11].
  • activating transcription factor 6's RefSeq protein ID is recorded as XP_011507612[12].
  • activating transcription factor 6's molecular function is recorded as DNA binding[13].
  • activating transcription factor 6's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding[14].
  • activating transcription factor 6's molecular function is recorded as DNA-binding transcription factor activity[15].
  • activating transcription factor 6's molecular function is recorded as transcription coactivator activity[16].
  • activating transcription factor 6's molecular function is recorded as transcription cis-regulatory region binding[17].
  • activating transcription factor 6's molecular function is recorded as protein binding[18].
  • activating transcription factor 6's molecular function is recorded as identical protein binding[19].
  • activating transcription factor 6's molecular function is recorded as protein heterodimerization activity[20].
  • activating transcription factor 6's molecular function is recorded as ubiquitin protein ligase binding[21].
  • activating transcription factor 6's molecular function is recorded as cAMP response element binding[22].
  • activating transcription factor 6's molecular function is recorded as RNA polymerase II cis-regulatory region sequence-specific DNA binding[23].
  • activating transcription factor 6's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific[24].
  • activating transcription factor 6's molecular function is recorded as sequence-specific DNA binding[25].
  • activating transcription factor 6's molecular function is recorded as DNA-binding transcription factor activity, RNA polymerase II-specific[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . Q20641742. Retrieved . wikidata.org.
  8. [9] . Q20641742. Retrieved . wikidata.org.
  9. [10] . Q20641742. Retrieved . wikidata.org.
  10. [11] . Q20641742. Retrieved . wikidata.org.
  11. [12] . Q20641742. Retrieved . wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . A thrombospondin-dependent pathway for a protective ER stress response. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . Impact of cytosine methylation on DNA binding specificities of human transcription factors.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . A census of human transcription factors: function, expression and evolution. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). activating transcription factor 6. Retrieved May 3, 2026, from https://4ort.xyz/entity/activating-transcription-factor-6-q21116808
MLA “activating transcription factor 6.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/activating-transcription-factor-6-q21116808.
BibTeX @misc{4ortxyz_activating-transcription-factor-6-q21116808_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{activating transcription factor 6}}, year = {2026}, url = {https://4ort.xyz/entity/activating-transcription-factor-6-q21116808}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): activating transcription factor 6 — https://4ort.xyz/entity/activating-transcription-factor-6-q21116808 (retrieved 2026-05-03)

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