4-hydroxy-2-oxoglutarate aldolase 1

mammalian protein found in Homo sapiens
Protein protein Q21118328
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4-hydroxy-2-oxoglutarate aldolase 1

Summary

4-hydroxy-2-oxoglutarate aldolase 1 is a protein[1].

Key Facts

  • 4-hydroxy-2-oxoglutarate aldolase 1's instance of is recorded as protein[2].
  • 4-hydroxy-2-oxoglutarate aldolase 1 is part of DapA-like[3].
  • 4-hydroxy-2-oxoglutarate aldolase 1 is part of TIM barrel[4].
  • 4-hydroxy-2-oxoglutarate aldolase 1 is part of Schiff base-forming aldolase, active site, protein family[5].
  • 4-hydroxy-2-oxoglutarate aldolase 1 comprises Schiff base-forming aldolase, active site[6].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as catalytic activity[7].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as protein homodimerization activity[8].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as lyase activity[9].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as 4-hydroxy-2-oxoglutarate aldolase activity[10].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as protein binding[11].
  • 4-hydroxy-2-oxoglutarate aldolase 1's molecular function is recorded as 4-hydroxy-2-oxoglutarate aldolase activity[12].
  • 4-hydroxy-2-oxoglutarate aldolase 1's cell component is recorded as mitochondrion[13].
  • 4-hydroxy-2-oxoglutarate aldolase 1's cell component is recorded as mitochondrial matrix[14].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as metabolism[15].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as pyruvate biosynthetic process[16].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as 4-hydroxyproline catabolic process[17].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as glyoxylate catabolic process[18].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as oxalate metabolic process[19].
  • 4-hydroxy-2-oxoglutarate aldolase 1's biological process is recorded as glyoxylate metabolic process[20].
  • 4-hydroxy-2-oxoglutarate aldolase 1's encoded by is recorded as HOGA1[21].
  • 4-hydroxy-2-oxoglutarate aldolase 1's found in taxon is recorded as Homo sapiens[22].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . Structural and biochemical studies of human 4-hydroxy-2-oxoglutarate aldolase: implications for hydroxyproline metabolism in primary hyperoxaluria. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . Mutations in DHDPSL Are Responsible For Primary Hyperoxaluria Type III. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Primary Hyperoxaluria Type III Gene HOGA1 (Formerly DHDPSL) as a Possible Risk Factor for Idiopathic Calcium Oxalate Urolithiasis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . Q905695. Retrieved . wikidata.org.
  21. [22] . Q905695. Retrieved . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). 4-hydroxy-2-oxoglutarate aldolase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/4-hydroxy-2-oxoglutarate-aldolase-1
MLA “4-hydroxy-2-oxoglutarate aldolase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/4-hydroxy-2-oxoglutarate-aldolase-1.
BibTeX @misc{4ortxyz_4-hydroxy-2-oxoglutarate-aldolase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{4-hydroxy-2-oxoglutarate aldolase 1}}, year = {2026}, url = {https://4ort.xyz/entity/4-hydroxy-2-oxoglutarate-aldolase-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): 4-hydroxy-2-oxoglutarate aldolase 1 — https://4ort.xyz/entity/4-hydroxy-2-oxoglutarate-aldolase-1 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 4w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from
    Encoded by HOGA1
    Wikidata description mammalian protein found in Homo sapiens
    Molecular function catalytic activity, protein homodimerization activity, lyase activity +3
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 4.1.3.16, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
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