3-hydroxy-3-methylglutaryl coenzyme A reductase

human protein (annotated by UniProtKB/TrEMBL A0A024RAP2)
Protein protein Q21141025
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3-hydroxy-3-methylglutaryl coenzyme A reductase

Summary

3-hydroxy-3-methylglutaryl coenzyme A reductase is a protein[1].

Key Facts

  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's instance of is recorded as protein[2].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's UniProt protein ID is recorded as A0A024RAP2[3].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, metazoan[4].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily[5].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily[6].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, N-terminal[7].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily[8].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Sterol-sensing domain, protein family[9].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site, protein family[10].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's has part is recorded as Sterol-sensing domain[11].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's has part is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site[12].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's RefSeq protein ID is recorded as NP_000850.1[13].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's RefSeq protein ID is recorded as XP_011541660.1[14].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor[15].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as protein homodimerization activity[16].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as hydroxymethylglutaryl-CoA reductase (NADPH) activity[17].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as NADP binding[18].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as oxidoreductase activity[19].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's molecular function is recorded as protein phosphatase 2A binding[20].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's cell component is recorded as integral component of membrane[21].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's cell component is recorded as endoplasmic reticulum membrane[22].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's cell component is recorded as intracellular membrane-bounded organelle[23].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's cell component is recorded as membrane[24].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's cell component is recorded as endoplasmic reticulum[25].
  • 3-hydroxy-3-methylglutaryl coenzyme A reductase's biological process is recorded as visual learning[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . wikidata.org.
  9. [10] . wikidata.org.
  10. [11] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Q905695. Retrieved . wikidata.org.
  13. [14] . Q905695. Retrieved . wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). 3-hydroxy-3-methylglutaryl coenzyme A reductase. Retrieved May 3, 2026, from https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coenzyme-a-reductase
MLA “3-hydroxy-3-methylglutaryl coenzyme A reductase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coenzyme-a-reductase.
BibTeX @misc{4ortxyz_3-hydroxy-3-methylglutaryl-coenzyme-a-reductase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{3-hydroxy-3-methylglutaryl coenzyme A reductase}}, year = {2026}, url = {https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coenzyme-a-reductase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): 3-hydroxy-3-methylglutaryl coenzyme A reductase — https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coenzyme-a-reductase (retrieved 2026-05-03)

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