3-hydroxy-3-methylglutaryl-CoA reductase

mammalian protein found in Homo sapiens
Protein protein Q415607
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3-hydroxy-3-methylglutaryl-CoA reductase

Summary

3-hydroxy-3-methylglutaryl-CoA reductase is a protein[1]. It ranks in the top 10% of protein entities by monthly Wikipedia readership (61 views/month).[2]

Key Facts

  • 3-hydroxy-3-methylglutaryl-CoA reductase's instance of is recorded as protein[3].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as atorvastatin[4].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as cerivastatin[5].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as fluvastatin[6].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as lovastatin[7].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as mevastatin[8].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as pravastatin[9].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as rosuvastatin[10].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's physically interacts with is recorded as simvastatin[11].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's UniProt protein ID is recorded as P04035[12].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, metazoan[13].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily[14].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily[15].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, N-terminal[16].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily[17].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Eukaryotic Sterol Transporter[18].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Sterol-sensing domain, protein family[19].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's part of is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site, protein family[20].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's Commons category is recorded as HMG-CoA reductase[21].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's has part is recorded as Sterol-sensing domain[22].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's has part is recorded as Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site[23].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's RefSeq protein ID is recorded as NP_000850[24].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's RefSeq protein ID is recorded as NP_001124468[25].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's RefSeq protein ID is recorded as XP_011541659[26].
  • 3-hydroxy-3-methylglutaryl-CoA reductase's RefSeq protein ID is recorded as XP_011541660[27].

Why It Matters

3-hydroxy-3-methylglutaryl-CoA reductase ranks in the top 10% of protein entities by monthly Wikipedia readership (61 views/month).[2] It has Wikipedia articles in 18 language editions, a strong signal of global cultural recognition.[28] It is known by 26 alternative names across languages and contexts.[29]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] . Q905695. Retrieved . wikidata.org.
  2. [4] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  4. [6] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  5. [7] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  6. [8] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  7. [9] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  8. [10] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  9. [11] . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  10. [12] . Q905695. Retrieved . wikidata.org.
  11. [13] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  12. [14] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  13. [15] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  14. [16] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  15. [17] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  16. [18] . Retrieved . wikidata.org.
  17. [19] . wikidata.org.
  18. [20] . wikidata.org.
  19. [21] . wikidata.org.
  20. [22] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  21. [23] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  22. [24] . Q20641742. Retrieved . wikidata.org.
  23. [25] . Q20641742. Retrieved . wikidata.org.
  24. [26] . Q20641742. Retrieved . wikidata.org.
  25. [27] . Q20641742. Retrieved . wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] . Wikidata sitelinks. wikidata.org.
  3. [29] . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). 3-hydroxy-3-methylglutaryl-CoA reductase. Retrieved May 3, 2026, from https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-reductase
MLA “3-hydroxy-3-methylglutaryl-CoA reductase.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-reductase.
BibTeX @misc{4ortxyz_3-hydroxy-3-methylglutaryl-coa-reductase_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{3-hydroxy-3-methylglutaryl-CoA reductase}}, year = {2026}, url = {https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-reductase}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): 3-hydroxy-3-methylglutaryl-CoA reductase — https://4ort.xyz/entity/3-hydroxy-3-methylglutaryl-coa-reductase (retrieved 2026-05-03)

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