2'-5'-oligoadenylate synthetase 1
mammalian protein found in Homo sapiens
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Summary
2'-5'-oligoadenylate synthetase 1 is a protein[1]. It is known by 13 alternative names across languages and contexts.[2]
Key Facts
- Part of: 2'-5'-oligoadenylate synthase[3], 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal domain, protein family[4], Polymerase, nucleotidyl transferase domain, protein family[5], 2-5-oligoadenylate synthetase, N-terminal domain, protein family[6], 2-5-oligoadenylate synthetase, C-terminal conserved site, protein family[7]
- Has part(s): 2-5-oligoadenylate synthetase, N-terminal[8], Polymerase, nucleotidyl transferase domain[9], 2'-5'-oligoadenylate synthetase 1, domain 2/C-terminal[10], 2-5-oligoadenylate synthetase, conserved site[11]
- Molecular function: transferase activity[12], nucleotide binding[13], nucleotidyltransferase activity[14], metal ion binding[15], protein binding[16], RNA binding[17], double-stranded RNA binding[18], ATP binding[19], 2'-5'-oligoadenylate synthetase activity[20]
- Cell component: cytoplasm[21], intracellular membrane-bounded organelle[22], extracellular region[23], endoplasmic reticulum[24], mitochondrion[25], nucleus[26], cytosol[27], nucleoplasm[28]
- Biological process: purine nucleotide biosynthetic process[29], regulation of ribonuclease activity[30], glucose homeostasis[31], interferon-gamma-mediated signaling pathway[32], immune system process[33], response to virus[34], negative regulation of viral genome replication[35], defense response to virus[36], type I interferon signaling pathway[37], protein complex oligomerization[38], immune response[39], glucose metabolic process[40], cellular response to interferon-alpha[41], innate immune response[42]
- Encoded by: OAS1[43]
- Found in taxon: Homo sapiens[44]
- Exact match: https://identifiers.org/uniprot:P00973[45], http://purl.uniprot.org/uniprot/P00973[46], https://www.ncbi.nlm.nih.gov/protein/P00973[47]