Home › Entities › protein › 2,4-dienoyl-CoA reductase 1

2,4-dienoyl-CoA reductase 1

mammalian protein found in Homo sapiens
Protein protein Q21101067
Press Enter · cited answer in seconds

Summary

2,4-dienoyl-CoA reductase 1 is a protein[1]. It is known by 8 alternative names across languages and contexts.[2]

Key Facts

  • Part of: NAD(P)-binding domain superfamily[3], Short-chain dehydrogenase/reductase SDR[4]
  • Molecular function: oxidoreductase activity, acting on NAD(P)H[5], oxidoreductase activity[6], 2,4-dienoyl-CoA reductase (NADPH) activity[7], NADPH binding[8]
  • Cell component: mitochondrial matrix[9], extracellular exosome[10], mitochondrion[11], nucleus[12], nucleoplasm[13], cytosol[14]
  • Biological process: fatty acid beta-oxidation[15], protein homotetramerization[16], fatty acid metabolic process[17], lipid metabolism[18], positive regulation of cold-induced thermogenesis[19]
  • Encoded by: DECR1[20]
  • Found in taxon: Homo sapiens[21]
  • Exact match: https://identifiers.org/uniprot:Q16698[22], http://purl.uniprot.org/uniprot/Q16698[23], https://www.ncbi.nlm.nih.gov/protein/Q16698[24]

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  2. [4] ↑ . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [5] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  4. [6] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  5. [7] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  6. [8] ↑ . Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  7. [9] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [10] ↑ . Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [11] ↑ . Isolation and characterization of cDNA for human 120 kDa mitochondrial 2,4-dienoyl-coenzyme A reductase. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [12] ↑ . Proteomic characterization of the human sperm nucleus. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [13] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [14] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [15] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [16] ↑ . Structure and reactivity of human mitochondrial 2,4-dienoyl-CoA reductase: enzyme-ligand interactions in a distinctive short-chain reductase active site. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [17] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [18] ↑ . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [19] ↑ . Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [20] ↑ . UniProt. Retrieved . wikidata.org.
  19. [21] ↑ . UniProt. Retrieved . wikidata.org.
  20. [22] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  21. [23] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.
  22. [24] ↑ . Identifiers.org. registry.identifiers.org. Provenance: wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). 2,4-dienoyl-CoA reductase 1. Retrieved May 3, 2026, from https://4ort.xyz/entity/2-4-dienoyl-coa-reductase-1
MLA “2,4-dienoyl-CoA reductase 1.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/2-4-dienoyl-coa-reductase-1.
BibTeX @misc{4ortxyz_2-4-dienoyl-coa-reductase-1_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{2,4-dienoyl-CoA reductase 1}}, year = {2026}, url = {https://4ort.xyz/entity/2-4-dienoyl-coa-reductase-1}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): 2,4-dienoyl-CoA reductase 1 — https://4ort.xyz/entity/2-4-dienoyl-coa-reductase-1 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/2-4-dienoyl-coa-reductase-1 · Last refreshed:

Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 12w ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Imported from → —
    Encoded by → DECR1
    Wikidata description → mammalian protein found in Homo sapiens
    Molecular function → oxidoreductase activity, acting on NAD(P)H, oxidoreductase activity, 2,4-dienoyl-CoA reductase (NADPH) activity +1
    + 11 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ Ec enzyme number: 1.3.1.124, [[:toollabs:quickstatements/#/batch/261488|batch #261488]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.