Tumor necrosis factor

mammalian protein found in Rattus norvegicus
Protein protein Q28556072
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Tumor necrosis factor

Summary

Tumor necrosis factor is a protein[1].

Key Facts

  • Tumor necrosis factor's instance of is recorded as protein[2].
  • Tumor necrosis factor's UniProt protein ID is recorded as P16599[3].
  • Tumor necrosis factor's part of is recorded as Tumour necrosis factor-like domain superfamily[4].
  • Tumor necrosis factor's part of is recorded as Tumour necrosis factor alpha[5].
  • Tumor necrosis factor's part of is recorded as membrane protein[6].
  • Tumor necrosis factor's part of is recorded as Tumour necrosis factor domain, protein family[7].
  • Tumor necrosis factor's part of is recorded as Tumour necrosis factor, conserved site, protein family[8].
  • Tumor necrosis factor's has part is recorded as Tumour necrosis factor, conserved site[9].
  • Tumor necrosis factor's has part is recorded as Tumour necrosis factor domain[10].
  • Tumor necrosis factor's RefSeq protein ID is recorded as NP_036807[11].
  • Tumor necrosis factor's molecular function is recorded as RNA polymerase II transcription regulatory region sequence-specific DNA binding[12].
  • Tumor necrosis factor's molecular function is recorded as cytokine activity[13].
  • Tumor necrosis factor's molecular function is recorded as tumor necrosis factor receptor binding[14].
  • Tumor necrosis factor's molecular function is recorded as cytokine activity[15].
  • Tumor necrosis factor's molecular function is recorded as tumor necrosis factor receptor binding[16].
  • Tumor necrosis factor's cell component is recorded as extracellular region[17].
  • Tumor necrosis factor's cell component is recorded as extracellular space[18].
  • Tumor necrosis factor's cell component is recorded as plasma membrane[19].
  • Tumor necrosis factor's cell component is recorded as external side of plasma membrane[20].
  • Tumor necrosis factor's cell component is recorded as membrane[21].
  • Tumor necrosis factor's cell component is recorded as integral component of membrane[22].
  • Tumor necrosis factor's cell component is recorded as cytoplasm[23].
  • Tumor necrosis factor's cell component is recorded as soma[24].
  • Tumor necrosis factor's cell component is recorded as extracellular space[25].
  • Tumor necrosis factor's cell component is recorded as cell surface[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . Q905695. Retrieved . wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . wikidata.org.
  7. [8] . wikidata.org.
  8. [9] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . Q20641742. Retrieved . wikidata.org.
  11. [12] . Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . Inhibitory cross-talk between STAT5b and liver nuclear factor HNF3beta: impact on the regulation of growth hormone pulse-stimulated, male-specific liver cytochrome P-450 gene expression. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . 14-Deoxyandrographolide desensitizes hepatocytes to tumour necrosis factor-alpha-induced apoptosis through calcium-dependent tumour necrosis factor receptor superfamily member 1A release via the NO/cGMP pathway. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . The effect of transmembrane- and secreted-tumor necrosis factor-alpha on shock liver. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Differential cellular expression of tumor necrosis factor-alpha and Type I tumor necrosis factor receptor after transient global forebrain ischemia. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). Tumor necrosis factor. Retrieved May 3, 2026, from https://4ort.xyz/entity/tumor-necrosis-factor-q28556072
MLA “Tumor necrosis factor.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/tumor-necrosis-factor-q28556072.
BibTeX @misc{4ortxyz_tumor-necrosis-factor-q28556072_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Tumor necrosis factor}}, year = {2026}, url = {https://4ort.xyz/entity/tumor-necrosis-factor-q28556072}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Tumor necrosis factor — https://4ort.xyz/entity/tumor-necrosis-factor-q28556072 (retrieved 2026-05-03)

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