Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

mammalian protein found in Mus musculus

Protein protein Q21991781

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Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

Summary

Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) is a protein^[1].

Key Facts

Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s instance of is recorded as protein^[2].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s UniProt protein ID is recorded as P36371^[3].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as ABC transporter type 1, transmembrane domain superfamily^[4].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as Antigen peptide transporter 2^[5].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as P-loop containing nucleoside triphosphate hydrolase^[6].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as AAA proteins^[7].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as ABC transporter-like, protein family^[8].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as ABC transporter type 1, transmembrane domain, protein family^[9].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s part of is recorded as ABC transporter, conserved site, protein family^[10].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s has part is recorded as AAA+ ATPase domain^[11].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s has part is recorded as ABC transporter-like^[12].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s has part is recorded as ABC transporter, conserved site^[13].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s has part is recorded as ABC transporter type 1, transmembrane domain^[14].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s RefSeq protein ID is recorded as NP_035660^[15].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as MHC protein binding^[16].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as ABC-type peptide transporter activity^[17].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as MHC class Ib protein binding^[18].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as ABC-type peptide antigen transporter activity^[19].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as ATPase activity^[20].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as protein binding^[21].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as TAP1 binding^[22].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as ATP binding^[23].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as ATPase-coupled transmembrane transporter activity^[24].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as peptide transmembrane transporter activity^[25].
Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)'s molecular function is recorded as nucleotide binding^[26].

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Quick Facts

Instance of protein

Part of ABC transporter type 1, transmembrane domain superfamily, Antigen peptide transporter 2, P-loop containing nucleoside triphosphate hydrolase, AAA proteins, ABC transporter-like, protein family, ABC transporter type 1, transmembrane domain, protein family, ABC transporter, conserved site, protein family

Properties

Biological process adaptive immune response, immune system process, positive regulation of T cell mediated cytotoxicity, antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent, antigen processing and presentation of endogenous peptide antigen via MHC class I, peptide antigen transport, protein transport, response to molecule of bacterial origin, antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent, cytosol to endoplasmic reticulum transport, antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent, transmembrane transport, positive regulation of antigen processing and presentation of peptide antigen via MHC class I, peptide transport, protection from natural killer cell mediated cytotoxicity, protein-containing complex assembly, peptide transport

Cell component endoplasmic reticulum membrane, TAP complex, integral component of endoplasmic reticulum membrane, integral component of membrane, endoplasmic reticulum, nuclear speck, membrane, MHC class I peptide loading complex, intracellular membrane-bounded organelle, integral component of membrane, endoplasmic reticulum

Encoded by Tap2

Found in taxon house mouse

Has part(s) AAA+ ATPase domain, ABC transporter-like, ABC transporter, conserved site, ABC transporter type 1, transmembrane domain

Imported from wholeness_audit_2026-05-02

Molecular function MHC protein binding, ABC-type peptide transporter activity, MHC class Ib protein binding, ABC-type peptide antigen transporter activity, ATPase activity, protein binding, TAP1 binding, ATP binding, ATPase-coupled transmembrane transporter activity, peptide transmembrane transporter activity, nucleotide binding, MHC class I protein binding, peptide antigen binding, protein homodimerization activity, ADP binding, TAP2 binding, tapasin binding, protein heterodimerization activity, ATPase-coupled transmembrane transporter activity, ABC-type peptide transporter activity, MHC class I protein binding, TAP1 binding, TAP2 binding, peptide transmembrane transporter activity

External References (3)

Ensembl protein id ENSMUSP00000118916, ENSMUSP00000025197, ENSMUSP00000118700

Refseq protein id NP_035660

Uniprot protein id P36371

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — UniProt protein ID (P352): P36371. Q905695. Retrieved 2022-05-25. wikidata.org.
[4] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): ABC transporter type 1, transmembrane domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[5] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): Antigen peptide transporter 2. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): P-loop containing nucleoside triphosphate hydrolase. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): AAA proteins. wikidata.org.
[8] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): ABC transporter-like, protein family. wikidata.org.
[9] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): ABC transporter type 1, transmembrane domain, protein family. wikidata.org.
[10] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — part of (P361): ABC transporter, conserved site, protein family. wikidata.org.
[11] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — has part(s) (P527): AAA+ ATPase domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[12] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — has part(s) (P527): ABC transporter-like. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[13] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — has part(s) (P527): ABC transporter, conserved site. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[14] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — has part(s) (P527): ABC transporter type 1, transmembrane domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[15] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — RefSeq protein ID (P637): NP_035660. Q20641742. Retrieved 2022-03-20. wikidata.org.
[16] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): MHC protein binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): ABC-type peptide transporter activity. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): MHC class Ib protein binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): ABC-type peptide antigen transporter activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): ATPase activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): protein binding. Association of beta2-microglobulin with the alpha3 domain of H-2Db heavy chain. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): TAP1 binding. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): ATP binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[24] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): ATPase-coupled transmembrane transporter activity. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): peptide transmembrane transporter activity. GOA. Retrieved 2018-09-10. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — molecular function (P680): nucleotide binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

4ort.xyz Knowledge Graph. (2026). Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP). Retrieved May 3, 2026, from https://4ort.xyz/entity/transporter-2-atp-binding-cassette-sub-family-b-mdr-tap-

MLA

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BibTeX

@misc{4ortxyz_transporter-2-atp-binding-cassette-sub-family-b-mdr-tap-_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)}}, year = {2026}, url = {https://4ort.xyz/entity/transporter-2-atp-binding-cassette-sub-family-b-mdr-tap-}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) — https://4ort.xyz/entity/transporter-2-atp-binding-cassette-sub-family-b-mdr-tap- (retrieved 2026-05-03)

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