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spironolactone

medication that is primarily used to treat fluid build-up due to heart failure, liver scarring, or kidney disease
ChemicalSubstance type_of_chemical_entity Q422188
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spironolactone

Summary

spironolactone is a type of chemical entity[1]. spironolactone ranks in the top 2% of type_of_chemical_entity entities by monthly Wikipedia readership (2,216 views/month).[2]

Key Facts

  • spironolactone's instance of is recorded as type of chemical entity[3].
  • spironolactone's physically interacts with is recorded as Nuclear receptor subfamily 3 group C member 2[4].
  • spironolactone's manufacturer is recorded as Pfizer[5].
  • spironolactone's canonical SMILES is recorded as CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C[6].
  • spironolactone's chemical formula is recorded as C₂₄H₃₂O₄S[7].
  • spironolactone is a type of ethanethioic acid S-(10,13-dimethyl-3,5'-dioxo-7-spiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]yl) ester[8].
  • spironolactone is used for medication[9].
  • spironolactone's Commons category is recorded as Spironolactone[10].
  • spironolactone's route of administration is recorded as oral administration[11].
  • spironolactone's significant drug interaction is recorded as nabumetone[12].
  • spironolactone's significant drug interaction is recorded as naproxen[13].
  • spironolactone's significant drug interaction is recorded as celecoxib[14].
  • spironolactone's significant drug interaction is recorded as Diclofenac[15].
  • spironolactone's significant drug interaction is recorded as piroxicam[16].
  • spironolactone's significant drug interaction is recorded as meloxicam[17].
  • spironolactone's significant drug interaction is recorded as (RS)-fenoprofen[18].
  • spironolactone's significant drug interaction is recorded as (±)-flurbiprofen[19].
  • spironolactone's significant drug interaction is recorded as ibuprofen[20].
  • spironolactone's significant drug interaction is recorded as (RS)-ketoprofen[21].
  • spironolactone's significant drug interaction is recorded as (RS)-etodolac[22].
  • spironolactone's significant drug interaction is recorded as sulindac[23].
  • spironolactone's significant drug interaction is recorded as parecoxib[24].
  • spironolactone's significant drug interaction is recorded as aceclofenac[25].
  • spironolactone's significant drug interaction is recorded as tenoxicam[26].
  • spironolactone's significant drug interaction is recorded as triamterene[27].

Why It Matters

spironolactone ranks in the top 2% of type_of_chemical_entity entities by monthly Wikipedia readership (2,216 views/month).[2] spironolactone has Wikipedia articles in 24 language editions, a strong signal of global cultural recognition.[28] spironolactone is known by 29 alternative names across languages and contexts.[29]

Related Entities

Pfizer

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [3] ↑ . wikidata.org.
  2. [4] ↑ . IUPHAR/BPS Guide to PHARMACOLOGY. Retrieved . wikidata.org.
  3. [5] ↑ . pfizer.com. pfizer.com. Provenance: wikidata.org.
  4. [6] ↑ . PubChem. Retrieved . wikidata.org.
  5. [7] ↑ . PubChem. Retrieved . wikidata.org.
  6. [8] ↑ . wikidata.org.
  7. [9] ↑ . wikidata.org.
  8. [10] ↑ . wikidata.org.
  9. [11] ↑ . wikidata.org.
  10. [12] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  11. [13] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  12. [14] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  13. [15] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  14. [16] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  15. [17] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  16. [18] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  17. [19] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  18. [20] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  19. [21] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  20. [22] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  21. [23] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  22. [24] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  23. [25] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  24. [26] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.
  25. [27] ↑ . A reference set of clinically relevant adverse drug-drug interactions. wikidata.org.

Class ancestry

  1. [1] ↑ . Wikidata. wikidata.org.

Aggregate / graph-position facts

  1. [2] ↑ . Wikimedia Foundation. dumps.wikimedia.org.
  2. [28] ↑ . Wikidata sitelinks. wikidata.org.
  3. [29] ↑ . Wikidata aliases. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). spironolactone. Retrieved October 6, 2026, from https://4ort.xyz/entity/spironolactone
MLA “spironolactone.” 4ort.xyz Knowledge Graph, 4ort.xyz, 6 Oct. 2026, https://4ort.xyz/entity/spironolactone.
BibTeX @misc{4ortxyz_spironolactone_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{spironolactone}}, year = {2026}, url = {https://4ort.xyz/entity/spironolactone}, note = {Accessed: 2026-10-06}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): spironolactone — https://4ort.xyz/entity/spironolactone (retrieved 2026-10-06)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 19w ago · Twofivesixbot bot · 2026-05-25 view diff on Wikidata ↗
    Subclass of → ethanethioic acid S-(10,13-dimethyl-3,5'-dioxo-7-spiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]yl) ester
    Route of administration → oral administration
    Has use → medication
    Stereoisomer of → 7|A-Spironolactone
    + 19 other properties edited (see Wikidata diff for full list)
    "/* wbsetclaim-update-qualifiers:1||1|3 */ [[Property:P8189]]: 987007529395005171, mv to monolingual text names on J9U statements"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.