sirtuin 3

mammalian protein found in Homo sapiens
Protein protein Q21116855
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sirtuin 3

Summary

sirtuin 3 is a protein[1].

Key Facts

  • sirtuin 3's instance of is recorded as protein[2].
  • sirtuin 3 is part of DHS-like NAD/FAD-binding domain superfamily[3].
  • sirtuin 3 is part of Sirtuin, class I[4].
  • sirtuin 3 is part of Sirtuin, catalytic core small domain superfamily[5].
  • sirtuin 3 is part of Sirtuin family, catalytic core domain, protein family[6].
  • sirtuin 3 comprises Sirtuin family, catalytic core domain[7].
  • sirtuin 3's molecular function is recorded as NAD+ ADP-ribosyltransferase activity[8].
  • sirtuin 3's molecular function is recorded as protein binding[9].
  • sirtuin 3's molecular function is recorded as hydrolase activity[10].
  • sirtuin 3's molecular function is recorded as NAD+ binding[11].
  • sirtuin 3's molecular function is recorded as metal ion binding[12].
  • sirtuin 3's molecular function is recorded as zinc ion binding[13].
  • sirtuin 3's molecular function is recorded as NAD-dependent histone deacetylase activity[14].
  • sirtuin 3's molecular function is recorded as NAD-dependent protein deacetylase activity[15].
  • sirtuin 3's molecular function is recorded as sequence-specific DNA binding[16].
  • sirtuin 3's molecular function is recorded as enzyme binding[17].
  • sirtuin 3's molecular function is recorded as NAD-dependent histone deacetylase activity[18].
  • sirtuin 3's molecular function is recorded as sequence-specific DNA binding[19].
  • sirtuin 3's molecular function is recorded as NAD+ binding[20].
  • sirtuin 3's cell component is recorded as mitochondrion[21].
  • sirtuin 3's cell component is recorded as mitochondrial matrix[22].
  • sirtuin 3's cell component is recorded as protein-containing complex[23].
  • sirtuin 3's cell component is recorded as cytoplasm[24].
  • sirtuin 3's cell component is recorded as mitochondrion[25].
  • sirtuin 3's cell component is recorded as mitochondrial matrix[26].

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

  1. [2] . Q905695. Retrieved . wikidata.org.
  2. [3] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  3. [4] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  4. [5] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  5. [6] . wikidata.org.
  6. [7] . InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
  7. [8] . Characterization of five human cDNAs with homology to the yeast SIR2 gene: Sir2-like proteins (sirtuins) metabolize NAD and may have protein ADP-ribosyltransferase activity. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  8. [9] . A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  9. [10] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  10. [11] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  11. [12] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  12. [13] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  13. [14] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  14. [15] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  15. [16] . Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  16. [17] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  17. [18] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  18. [19] . Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  19. [20] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  20. [21] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  21. [22] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  22. [23] . Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  23. [24] . Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  24. [25] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.
  25. [26] . GOA. Retrieved . ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

  1. [1] . Wikidata. wikidata.org.

📑 Cite this page

Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA 4ort.xyz Knowledge Graph. (2026). sirtuin 3. Retrieved May 3, 2026, from https://4ort.xyz/entity/sirtuin-3
MLA “sirtuin 3.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/sirtuin-3.
BibTeX @misc{4ortxyz_sirtuin-3_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{sirtuin 3}}, year = {2026}, url = {https://4ort.xyz/entity/sirtuin-3}, note = {Accessed: 2026-05-03}}
LLM prompt According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): sirtuin 3 — https://4ort.xyz/entity/sirtuin-3 (retrieved 2026-05-03)

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Edit History

Rolling log of changes to this entity's Wikidata record. Values shown reflect the current state of each edited property — follow the history link to see the precise diff for any edit.

  1. 27d ago · Boghog · 2026-07-24 view diff on Wikidata ↗
    Found in taxon Homo sapiens
    Mesh tree code D08.811.277.087.520.200.650.600, D08.811.913.400.725.115.961.600, D12.776.476.900.600 +1
    Wikidata description mammalian protein found in Homo sapiens
    Pdb structure id 3GLR, 3GLS, 3GLU +21
    + 14 other properties edited (see Wikidata diff for full list)
    "/* wbcreateclaim-create:1| */ [[Property:P591]]: 2.3.1.286, [[:toollabs:quickstatements/#/batch/261491|batch #261491]]"
Live feed via Wikidata EventStreams. New edits appear within minutes of being made on Wikidata.