Signal transducer and activator of transcription 6

mammalian protein found in Mus musculus

Protein protein Q14914616

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Signal transducer and activator of transcription 6

Summary

Signal transducer and activator of transcription 6 is a protein^[1].

Key Facts

Signal transducer and activator of transcription 6's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 6's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 6's UniProt protein ID is recorded as P52633^[4].
Signal transducer and activator of transcription 6's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[6].
Signal transducer and activator of transcription 6's part of is recorded as transcription factor STAT^[7].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 6's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 6's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 6's part of is recorded as STAT6, SH2 domain, protein family^[13].
Signal transducer and activator of transcription 6's part of is recorded as STAT6, C-terminal domain, protein family^[14].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[15].
Signal transducer and activator of transcription 6's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[16].
Signal transducer and activator of transcription 6's has part is recorded as STAT transcription factor, DNA-binding^[17].
Signal transducer and activator of transcription 6's has part is recorded as SH2 domain^[18].
Signal transducer and activator of transcription 6's has part is recorded as STAT transcription factor, all-alpha domain^[19].
Signal transducer and activator of transcription 6's has part is recorded as STAT transcription factor, protein interaction^[20].
Signal transducer and activator of transcription 6's has part is recorded as STAT6, C-terminal^[21].
Signal transducer and activator of transcription 6's has part is recorded as STAT6, SH2 domain^[22].
Signal transducer and activator of transcription 6's RefSeq protein ID is recorded as NP_033310^[23].
Signal transducer and activator of transcription 6's molecular function is recorded as DNA binding^[24].
Signal transducer and activator of transcription 6's molecular function is recorded as DNA-binding transcription activator activity, RNA polymerase II-specific^[25].
Signal transducer and activator of transcription 6's molecular function is recorded as DNA-binding transcription repressor activity, RNA polymerase II-specific^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT transcription factor, DNA-binding, N-terminal, transcription factor STAT, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT6, SH2 domain, protein family, STAT6, C-terminal domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT transcription factor, all-alpha domain, protein family

Properties

Biological process mammary gland epithelial cell proliferation, positive regulation of isotype switching to IgE isotypes, regulation of transcription, DNA-templated, interleukin-4-mediated signaling pathway, T-helper 1 cell lineage commitment, mammary gland morphogenesis, negative regulation of transcription by RNA polymerase II, transcription, DNA-templated, regulation of cell population proliferation, negative regulation of type 2 immune response, signal transduction, transcription by RNA polymerase II, positive regulation of transcription by RNA polymerase II, cytokine-mediated signaling pathway, response to cytokine, cellular response to hydrogen peroxide, cellular response to reactive nitrogen species, positive regulation of cold-induced thermogenesis, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II, growth hormone receptor signaling pathway via JAK-STAT

Cell component nucleoplasm, cytoplasm, cytosol, nuclear membrane, nucleus, membrane raft, nucleus, cytosol

Encoded by Stat6

Found in taxon house mouse

Has part(s) STAT transcription factor, DNA-binding, SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, protein interaction, STAT6, C-terminal, STAT6, SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, DNA-binding transcription repressor activity, RNA polymerase II-specific, identical protein binding, protein phosphatase binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription factor activity, sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (3)

Ensembl protein id ENSMUSP00000089708, ENSMUSP00000112722

Refseq protein id NP_033310

Uniprot protein id P52633

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 6 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 6 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 6 — UniProt protein ID (P352): P52633. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 6 — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 6 — part of (P361): transcription factor STAT. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 6 — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 6 — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT6, SH2 domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT6, C-terminal domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[16] ↑ Signal transducer and activator of transcription 6 — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[17] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): STAT6, C-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[22] ↑ Signal transducer and activator of transcription 6 — has part(s) (P527): STAT6, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[23] ↑ Signal transducer and activator of transcription 6 — RefSeq protein ID (P637): NP_033310. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 6 — molecular function (P680): DNA binding. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.
[25] ↑ Signal transducer and activator of transcription 6 — molecular function (P680): DNA-binding transcription activator activity, RNA polymerase II-specific. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.
[26] ↑ Signal transducer and activator of transcription 6 — molecular function (P680): DNA-binding transcription repressor activity, RNA polymerase II-specific. GOA. Retrieved 2018-04-24. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 6 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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APA

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MLA

“Signal transducer and activator of transcription 6.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-6.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-6_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 6}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-6}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 6 — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-6 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-6 · Last refreshed: May 3, 2026