Signal transducer and activator of transcription 4

mammalian protein found in Mus musculus

Protein protein Q14914620

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Signal transducer and activator of transcription 4

Summary

Signal transducer and activator of transcription 4 is a protein^[1].

Key Facts

Signal transducer and activator of transcription 4's instance of is recorded as protein^[2].
Signal transducer and activator of transcription 4's subclass of is recorded as protein^[3].
Signal transducer and activator of transcription 4's UniProt protein ID is recorded as P42228^[4].
Signal transducer and activator of transcription 4's part of is recorded as p53-like transcription factor, DNA-binding^[5].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, DNA-binding, N-terminal^[6].
Signal transducer and activator of transcription 4's part of is recorded as Signal transducer and activator of transcription 4^[7].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, coiled coil^[8].
Signal transducer and activator of transcription 4's part of is recorded as SH2 domain superfamily^[9].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, N-terminal domain superfamily^[10].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, protein interaction, protein family^[11].
Signal transducer and activator of transcription 4's part of is recorded as SH2 domain, protein family^[12].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, DNA-binding domain, protein family^[13].
Signal transducer and activator of transcription 4's part of is recorded as STAT transcription factor, all-alpha domain, protein family^[14].
Signal transducer and activator of transcription 4's part of is recorded as STAT4, SH2 domain, protein family^[15].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, DNA-binding^[16].
Signal transducer and activator of transcription 4's has part is recorded as SH2 domain^[17].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, all-alpha domain^[18].
Signal transducer and activator of transcription 4's has part is recorded as STAT transcription factor, protein interaction^[19].
Signal transducer and activator of transcription 4's has part is recorded as STAT4, SH2 domain^[20].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as NP_001295195^[21].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as NP_035617^[22].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as XP_006495878^[23].
Signal transducer and activator of transcription 4's RefSeq protein ID is recorded as XP_006495879^[24].
Signal transducer and activator of transcription 4's PDB structure ID is recorded as 1BGF^[25].
Signal transducer and activator of transcription 4's molecular function is recorded as DNA-binding transcription factor activity^[26].

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Quick Facts

Instance of protein

Subclass of protein

Part of p53-like transcription factor, DNA-binding, STAT transcription factor, DNA-binding, N-terminal, Signal transducer and activator of transcription 4, STAT transcription factor, coiled coil, SH2 domain superfamily, STAT transcription factor, N-terminal domain superfamily, STAT transcription factor, protein interaction, protein family, SH2 domain, protein family, STAT transcription factor, DNA-binding domain, protein family, STAT transcription factor, all-alpha domain, protein family, STAT4, SH2 domain, protein family

Properties

Biological process cellular response to organic substance, protein phosphorylation, cell population proliferation, regulation of transcription, DNA-templated, transcription, DNA-templated, signal transduction, cytokine-mediated signaling pathway, positive regulation of transcription by RNA polymerase II, transcription by RNA polymerase II, positive regulation of gene expression, defense response, receptor signaling pathway via JAK-STAT, cytokine-mediated signaling pathway, regulation of cell population proliferation, response to peptide hormone, positive regulation of transcription by RNA polymerase II

Cell component cytoplasm, cytosol, nucleus, nucleus, cytosol

Encoded by Stat4

Found in taxon house mouse

Has part(s) STAT transcription factor, DNA-binding, SH2 domain, STAT transcription factor, all-alpha domain, STAT transcription factor, protein interaction, STAT4, SH2 domain

Imported from wholeness_audit_2026-05-02

Molecular function DNA-binding transcription factor activity, DNA binding, protein binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, identical protein binding, sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific

External References (4)

Ensembl protein id ENSMUSP00000027277, ENSMUSP00000130713

Pdb structure id 1BGF

Refseq protein id NP_001295195, NP_035617, XP_006495878, XP_006495879

Uniprot protein id P42228

References

Programmatic citations — every numbered marker resolves to a verifiable graph row below.

Direct Wikidata claims

[2] ↑ Signal transducer and activator of transcription 4 — instance of (P31): protein. Q905695. Retrieved 2022-05-25. wikidata.org.
[3] ↑ Signal transducer and activator of transcription 4 — subclass of (P279): protein. Q905695. Retrieved 2017-01-19. wikidata.org.
[4] ↑ Signal transducer and activator of transcription 4 — UniProt protein ID (P352): P42228. Q905695. Retrieved 2022-05-25. wikidata.org.
[5] ↑ Signal transducer and activator of transcription 4 — part of (P361): p53-like transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[6] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, DNA-binding, N-terminal. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[7] ↑ Signal transducer and activator of transcription 4 — part of (P361): Signal transducer and activator of transcription 4. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[8] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, coiled coil. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[9] ↑ Signal transducer and activator of transcription 4 — part of (P361): SH2 domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[10] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, N-terminal domain superfamily. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[11] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, protein interaction, protein family. wikidata.org.
[12] ↑ Signal transducer and activator of transcription 4 — part of (P361): SH2 domain, protein family. wikidata.org.
[13] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, DNA-binding domain, protein family. wikidata.org.
[14] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT transcription factor, all-alpha domain, protein family. wikidata.org.
[15] ↑ Signal transducer and activator of transcription 4 — part of (P361): STAT4, SH2 domain, protein family. wikidata.org.
[16] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, DNA-binding. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[17] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[18] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, all-alpha domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[19] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT transcription factor, protein interaction. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[20] ↑ Signal transducer and activator of transcription 4 — has part(s) (P527): STAT4, SH2 domain. InterPro Release 71.0. ebi.ac.uk. Provenance: wikidata.org.
[21] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): NP_001295195. Q20641742. Retrieved 2022-03-20. wikidata.org.
[22] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): NP_035617. Q20641742. Retrieved 2022-03-20. wikidata.org.
[23] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): XP_006495878. Q20641742. Retrieved 2022-03-20. wikidata.org.
[24] ↑ Signal transducer and activator of transcription 4 — RefSeq protein ID (P637): XP_006495879. Q20641742. Retrieved 2022-03-20. wikidata.org.
[25] ↑ Signal transducer and activator of transcription 4 — PDB structure ID (P638): 1BGF. Q905695. Retrieved 2016-08-09. wikidata.org.
[26] ↑ Signal transducer and activator of transcription 4 — molecular function (P680): DNA-binding transcription factor activity. GOA. Retrieved 2019-05-09. ebi.ac.uk. Provenance: wikidata.org.

Class ancestry

[1] ↑ Signal transducer and activator of transcription 4 is an instance of protein (Q8054) [P31, primary]. Wikidata. wikidata.org.

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Use these citations when quoting this entity in research, articles, AI prompts, or wherever provenance matters. We aggregate Wikidata + Wikipedia + authoritative open-data sources; the stitched, scored, cross-referenced view is what 4ort.xyz contributes.

APA

4ort.xyz Knowledge Graph. (2026). Signal transducer and activator of transcription 4. Retrieved May 3, 2026, from https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4

MLA

“Signal transducer and activator of transcription 4.” 4ort.xyz Knowledge Graph, 4ort.xyz, 3 May. 2026, https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4.

BibTeX

@misc{4ortxyz_signal-transducer-and-activator-of-transcription-4_2026, author = {{4ort.xyz Knowledge Graph}}, title = {{Signal transducer and activator of transcription 4}}, year = {2026}, url = {https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4}, note = {Accessed: 2026-05-03}}

LLM prompt

According to 4ort.xyz Knowledge Graph (aggregator of Wikidata, Wikipedia, and authoritative open-data sources): Signal transducer and activator of transcription 4 — https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4 (retrieved 2026-05-03)

Canonical URL: https://4ort.xyz/entity/signal-transducer-and-activator-of-transcription-4 · Last refreshed: May 3, 2026